PMID- 36107552
OWN - NLM
STAT- MEDLINE
DCOM- 20220919
LR  - 20220919
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 101
IP  - 35
DP  - 2022 Sep 2
TI  - Transcranial direct current stimulation in the treatment of anxiety and 
      depression in patients with oral cancer during perioperative period.
PG  - e30220
LID - 10.1097/MD.0000000000030220 [doi]
LID - e30220
AB  - This study retrospectively investigated the efficacy of transcranial direct 
      current stimulation (tDCS) in the treatment of anxiety and depression in patients 
      with oral cancer (OC) during the perioperative period (PPP). This retrospective 
      study reviewed the electronic medical records of patients who underwent OC 
      surgery and experienced anxiety and depression during PPP. The patients were 
      divided into the treatment (n = 36) and control (n = 36) groups. The patients in 
      the treatment group received tDCS, whereas those in the control group did not 
      receive tDCS. The primary outcomes included the Self-rating Anxiety Scale (SAS) 
      and the Self-rating Depression Scale (SDS). Secondary outcomes included adverse 
      events (AEs). We analyzed the outcome data before and after treatment. After 
      treatment, patients in the treatment group achieved greater relief in SAS (P < 
      .01) and SDS (P < .01) scores than those in the control group. Regarding safety, 
      no electronic medical records reported any AEs in this study. The results of this 
      study showed that tDCS may help relieve depression and anxiety in patients with 
      OC during PPP. However, high-quality prospective randomized controlled trials are 
      required to confirm these findings.
CI  - Copyright (c) 2022 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Gao, Zhi-Biao
AU  - Gao ZB
AD  - Department of Oral and Maxillofacial Surgery, Yanan University Affiliated 
      Hospital, Yan'an, China.
FAU - Zhang, Wen-Juan
AU  - Zhang WJ
AD  - Department of Oral and Maxillofacial Surgery, Yanan University Affiliated 
      Hospital, Yan'an, China.
FAU - Tuo, Rui
AU  - Tuo R
AD  - Department of Oral and Maxillofacial Surgery, Yanan University Affiliated 
      Hospital, Yan'an, China.
FAU - Xiao, Xia
AU  - Xiao X
AD  - Department of Oral and Maxillofacial Surgery, Yanan University Affiliated 
      Hospital, Yan'an, China.
FAU - Cao, Wei-Jing
AU  - Cao WJ
AUID- ORCID: 0000-0002-7631-19510000-0002-7631-1951
AD  - Department of Periodontology, Yanan University Affiliated Hospital, Yan'an, 
      China.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Anxiety/etiology/therapy
MH  - Depression/etiology/therapy
MH  - Humans
MH  - *Mouth Neoplasms/complications/surgery
MH  - Perioperative Period
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - *Transcranial Direct Current Stimulation/methods
PMC - PMC9439821
COIS- All authors declared no competing interest in this study.
EDAT- 2022/09/16 06:00
MHDA- 2022/09/20 06:00
PMCR- 2022/09/02
CRDT- 2022/09/15 11:54
PHST- 2022/09/15 11:54 [entrez]
PHST- 2022/09/16 06:00 [pubmed]
PHST- 2022/09/20 06:00 [medline]
PHST- 2022/09/02 00:00 [pmc-release]
AID - 00005792-202209020-00116 [pii]
AID - 10.1097/MD.0000000000030220 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2022 Sep 2;101(35):e30220. doi: 
      10.1097/MD.0000000000030220.