PMID- 36111930
OWN - NLM
STAT- MEDLINE
DCOM- 20220920
LR  - 20221216
IS  - 2284-0729 (Electronic)
IS  - 1128-3602 (Linking)
VI  - 26
IP  - 17
DP  - 2022 Sep
TI  - Comparative analysis between mono approach and multi approaches in managing T2DM: 
      a survey-based study.
PG  - 6290-6299
LID - 29653 [pii]
LID - 10.26355/eurrev_202209_29653 [doi]
AB  - OBJECTIVE: The aim of the study was to analytically compare the therapeutic 
      effect of the addition of diet modification and regular exercise to oral agents. 
      MATERIALS AND METHODS: This cross-sectional study surveyed 1248 participants via 
      online and offline modes by employing a questionnaire about an individual's 
      management of diabetes. Group 1 patients follow Single Approach Management for 
      Type 2 Diabetes Mellitus (T2DM), while Group 2 and Group 3 patients follow 
      Multi-Approach Management for T2DM. Based on the answers, the participants were 
      classified into three groups. The diagnostic criteria of Diabetes Mellitus Type-2 
      in this study were done by determining morning Fasting Blood Sugar (FBS) and 
      glycated Hemoglobin (HbA1c). RESULTS: The current study found 656 single oral 
      agent users and 592 combination regimens users among all the study participants. 
      The study also found that, among all participants, 511 patients were on mild to 
      moderate diet modification while 325 patients were on moderate to severe diet 
      modification. The study also noted that 232 males and 215 females took 
      Complementary and Alternative Medicines (CAM). Of 447 patients, 12 showed 
      menstrual abnormalities (2.6%), and 18 had mild diarrhoea (4%). The study also 
      found that there is a vital significance of lowering FBS and HbA1c with the 
      management strategies (p=0.000). The study showed a strong association between 
      group 3 and improved FBS and HbA1c (p=0.000). CONCLUSIONS: This study reveals 
      that diet modification and regular exercise improve FBS and HbA1c levels 
      significantly. Hence, diet modification and exercise can be added as adjuvants 
      and should be incorporated into the management guidelines of T2DM.
FAU - Alanazi, M
AU  - Alanazi M
AD  - Department of Clinical Pharmacy, Department of Pharmaceutical Chemistry, College 
      of Pharmacy, University of Hail, Hail, Kingdom Saudi Arabia. 
      drunnisa.aziz10@gmail.com.
FAU - Unnisa, A
AU  - Unnisa A
FAU - Patel, R D
AU  - Patel RD
FAU - Alanazi, J
AU  - Alanazi J
FAU - Khalid, M
AU  - Khalid M
FAU - Ahmad, S
AU  - Ahmad S
FAU - Jandrajupalli, S B
AU  - Jandrajupalli SB
FAU - Hussain, T
AU  - Hussain T
FAU - Abobaker, S H
AU  - Abobaker SH
FAU - Chandolu, S
AU  - Chandolu S
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Eur Rev Med Pharmacol Sci
JT  - European review for medical and pharmacological sciences
JID - 9717360
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
SB  - IM
MH  - Blood Glucose/analysis
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus, Type 2/diagnosis/therapy
MH  - Female
MH  - Glycated Hemoglobin/analysis
MH  - Humans
MH  - Male
MH  - Surveys and Questionnaires
EDAT- 2022/09/17 06:00
MHDA- 2022/09/21 06:00
CRDT- 2022/09/16 09:13
PHST- 2022/09/16 09:13 [entrez]
PHST- 2022/09/17 06:00 [pubmed]
PHST- 2022/09/21 06:00 [medline]
AID - 29653 [pii]
AID - 10.26355/eurrev_202209_29653 [doi]
PST - ppublish
SO  - Eur Rev Med Pharmacol Sci. 2022 Sep;26(17):6290-6299. doi: 
      10.26355/eurrev_202209_29653.