PMID- 36116655 OWN - NLM STAT- MEDLINE DCOM- 20221123 LR - 20221123 IS - 1879-1026 (Electronic) IS - 0048-9697 (Linking) VI - 856 IP - Pt 1 DP - 2023 Jan 15 TI - Environmental risks from consumer products: Acceptable drinking water quality can produce unacceptable indoor air quality with ultrasonic humidifier use. PG - 158787 LID - S0048-9697(22)05886-7 [pii] LID - 10.1016/j.scitotenv.2022.158787 [doi] AB - The commonly used consumer product of an ultrasonic humidifier (e.g., cool mist humidifier) emits fine particles containing metals from tap water used to fill the humidifier. The objectives are: 1) predict emitted indoor air inhalable metal concentrations produced by an ultrasonic humidifier filled with tap-water containing As, Cd, Cr, Cu, Mn, and Pb in 33 m(3) or 72 m(3) rooms with varying air exchange rates; 2) calculate daily ingestion and 8-h inhalation average daily dose (ADD) and hazard quotient (HQ) for adults and children (aged 0.25-6 yr); and 3) quantify deposition in respiratory tract via multi-path particle dosimetry (MPPD) model. Mass concentrations of indoor air metals increase proportionally with aqueous metal concentrations in fill water, and are inversely related to ventilation. Inhalation-ADDs are 2 magnitudes lower than ingestion-ADDs, using identical water quality for ingestion and fill-water. However, in the 33 m(3), low 0.2/h ventilated room, inhalation-HQs are >1 for children and adults, except for Pb. HQ inhalation risks exceed ingestion risks at drinking water regulated levels for As, Cd, Cr, and Mn. MPPD shows greater dose deposits in lungs of children than adults, and 3 times greater deposited doses in a 33 m(3) vs 72 m(3) room. Rethinking health effects of drinking water and consumer products to broaden consideration of multiple exposure routes is needed. CI - Copyright (c) 2022 Elsevier B.V. All rights reserved. FAU - Dietrich, Andrea M AU - Dietrich AM AD - Department of Civil & Environmental Engineering, Virginia Tech, Blacksburg, VA, USA. Electronic address: andread@vt.edu. FAU - Yao, Wenchuo AU - Yao W AD - Department of Civil & Environmental Engineering, Virginia Tech, Blacksburg, VA, USA. FAU - Gohlke, Julia M AU - Gohlke JM AD - Department of Population Health Sciences, Virginia Tech, Blacksburg, VA, USA. FAU - Gallagher, Daniel L AU - Gallagher DL AD - Department of Civil & Environmental Engineering, Virginia Tech, Blacksburg, VA, USA. LA - eng PT - Journal Article DEP - 20220916 PL - Netherlands TA - Sci Total Environ JT - The Science of the total environment JID - 0330500 RN - 0 (Drinking Water) RN - 00BH33GNGH (Cadmium) RN - 2P299V784P (Lead) RN - 0 (Metals, Heavy) SB - IM MH - Child MH - Adult MH - Humans MH - *Air Pollution, Indoor/analysis MH - Humidifiers MH - *Drinking Water MH - Water Quality MH - Cadmium MH - Ultrasonics MH - Lead MH - Risk Assessment MH - Environmental Monitoring MH - *Metals, Heavy/analysis OTO - NOTNLM OT - Children health OT - Indoor air quality OT - Inhalation toxicity OT - Inorganic metals OT - Risk assessment OT - Ultrasonic humidifier COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2022/09/19 06:00 MHDA- 2022/11/24 06:00 CRDT- 2022/09/18 19:25 PHST- 2022/07/25 00:00 [received] PHST- 2022/09/10 00:00 [revised] PHST- 2022/09/11 00:00 [accepted] PHST- 2022/09/19 06:00 [pubmed] PHST- 2022/11/24 06:00 [medline] PHST- 2022/09/18 19:25 [entrez] AID - S0048-9697(22)05886-7 [pii] AID - 10.1016/j.scitotenv.2022.158787 [doi] PST - ppublish SO - Sci Total Environ. 2023 Jan 15;856(Pt 1):158787. doi: 10.1016/j.scitotenv.2022.158787. Epub 2022 Sep 16.