PMID- 36118637
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220920
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 10
IP  - 9
DP  - 2022 Sep
TI  - Gel immersion endoscopic submucosal dissection: clinical experience with 13 cases 
      of superficial esophageal cancer.
PG  - E1302-E1306
LID - 10.1055/a-1894-0719 [doi]
AB  - Esophageal endoscopic submucosal dissection (ESD) of tumors located on the 
      gravity side is technically challenging. Given that gel immersion ESD (GIESD) is 
      performed by immersing lesions in gel, we hypothesized that it could be used to 
      eliminate the disadvantage associated with submerging the gravity side. Here, we 
      performed GIESD using VISCOCLEAR for superficial esophageal cancer on the gravity 
      side of the esophagus, with monopolar devices. This study aimed to evaluate the 
      short-term outcomes of GIESD for superficial esophageal cancer. Fifteen patients 
      with 16 superficial esophageal cancers underwent GIESD by a single operator, and 
      13 cases were evaluated. All patients were male, and GIESD was performed in the 
      middle (12/13, 92.3 %) and lower (1/13, 7.7 %) thoracic esophagus. The lesions 
      were located on the left (7/13, 53.8 %), posterior (5/13, 38.5 %), and right 
      (1/13, 7.7 %) esophageal walls. The median procedure time was 27 minutes 
      (interquartile range [IQR], 14-68), and the median dissection speed was 20 mm (2) 
      /min (IQR, 14-25.7). The median amount of gel used was 400 mL (IQR, 360-580), and 
      no gel-related adverse events were observed. The median total dose of midazolam 
      was 3 mg (IQR, 2-5). GIESD was completed with en bloc and R0 resections achieved 
      in 100 % of the 13 cases. Delayed adverse events, such as bleeding or 
      perforation, did not occur (0/13, 0 %).
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution-NonDerivative-NonCommercial License, 
      permitting copying and reproduction so long as the original work is given 
      appropriate credit. Contents may not be used for commercial purposes, or adapted, 
      remixed, transformed or built upon. 
      (https://creativecommons.org/licenses/by-nc-nd/4.0/).
FAU - Nakano, Yuya
AU  - Nakano Y
AD  - Department of Gastroenterology, Saitama Medical University International Medical 
      Center, Saitama, Japan.
FAU - Tashima, Tomoaki
AU  - Tashima T
AD  - Department of Gastroenterology, Saitama Medical University International Medical 
      Center, Saitama, Japan.
FAU - Jinushi, Ryuhei
AU  - Jinushi R
AD  - Department of Gastroenterology, Saitama Medical University International Medical 
      Center, Saitama, Japan.
FAU - Terada, Rie
AU  - Terada R
AD  - Department of Gastroenterology, Saitama Medical University International Medical 
      Center, Saitama, Japan.
FAU - Mashimo, Yumi
AU  - Mashimo Y
AD  - Department of Gastroenterology, Saitama Medical University International Medical 
      Center, Saitama, Japan.
FAU - Kawasaki, Tomonori
AU  - Kawasaki T
AD  - Department of Pathology, Saitama Medical University International Medical Center, 
      Saitama, Japan.
FAU - Uraoka, Toshio
AU  - Uraoka T
AD  - Department of Gastroenterology and Hepatology, Graduate School of Medicine, Gunma 
      University, Gunma, Japan.
FAU - Ryozawa, Shomei
AU  - Ryozawa S
AD  - Department of Gastroenterology, Saitama Medical University International Medical 
      Center, Saitama, Japan.
LA  - eng
PT  - Journal Article
DEP - 20220914
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC9473821
COIS- Competing interests The authors declare that they have no conflict of interest.
EDAT- 2022/09/20 06:00
MHDA- 2022/09/20 06:01
PMCR- 2022/09/01
CRDT- 2022/09/19 04:14
PHST- 2022/02/25 00:00 [received]
PHST- 2022/07/04 00:00 [accepted]
PHST- 2022/09/19 04:14 [entrez]
PHST- 2022/09/20 06:00 [pubmed]
PHST- 2022/09/20 06:01 [medline]
PHST- 2022/09/01 00:00 [pmc-release]
AID - 10.1055/a-1894-0719 [doi]
PST - epublish
SO  - Endosc Int Open. 2022 Sep 14;10(9):E1302-E1306. doi: 10.1055/a-1894-0719. 
      eCollection 2022 Sep.