PMID- 36118744 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20231103 IS - 2296-861X (Print) IS - 2296-861X (Electronic) IS - 2296-861X (Linking) VI - 9 DP - 2022 TI - Residue, dissipation, and dietary intake evaluation of fenpyroximate acaricide in/on guava, orange, and eggplant under open field condition. PG - 939012 LID - 10.3389/fnut.2022.939012 [doi] LID - 939012 AB - Fenpyroximate is a widely used acaricide applicable in many crops. In this study, the residue behavior of fenpyroximate on eggplant, orange, and guava was investigated. The chronic and acute dietary intake was calculated at several sampling points, and preharvest intervals (PHI) were proposed to ensure compliance with the existing maximum residue levels. A simple extraction protocol combined with ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) was employed to quantify residue levels. The method was successfully validated according to the European Union (EU) guidelines, and a limit of quantification of 0.01 mg/kg was set. The dissipation patterns in all crops could be described by the first-order kinetics model with half-lives of 1.7, 2.2, and 1.9 days for eggplants, guavas, and oranges, respectively. The dietary risk assessment at the authorized or more critical application patterns was acceptable for the consumers. For oranges and eggplant, a PHI of 3 and 7 days, respectively, can be proposed; however, a proposal was not possible for guava due to the absence of maximum residue limits (MRLs) and quantitative residue findings at all sampling points tested. The current work not only contributes to the practical application of fenpyroximate related to residue management in dryland areas, such as Egypt, but can also be used to estimate the appropriate PHIs and support the authorization of plant protection products as supplementary information. CI - Copyright (c) 2022 Malhat, Abdallah, Anagnostopoulos, Hussien, Purnama, Helmy, Soliman and El-Hefny. FAU - Malhat, Farag AU - Malhat F AD - Pesticide Residues and Environmental Pollution Department, Central Agricultural Pesticide Laboratory, Agricultural Research Center, Giza, Egypt. FAU - Abdallah, Osama AU - Abdallah O AD - Pesticide Residues and Environmental Pollution Department, Central Agricultural Pesticide Laboratory, Agricultural Research Center, Giza, Egypt. FAU - Anagnostopoulos, Chris AU - Anagnostopoulos C AD - Benaki Phytopathological Institute, Department of Pesticides Control and Phytopharmacy, Laboratory of Pesticides Residues, Athens, Greece. FAU - Hussien, Mohamed AU - Hussien M AD - Department of Chemistry, Faculty of Science, King Khalid University, Abha, Saudi Arabia. FAU - Purnama, Indra AU - Purnama I AD - Department of Agrotechnology, Universitas Lancang Kuning, Pekanbaru, Indonesia. FAU - Helmy, Rania M A AU - Helmy RMA AD - Pesticide Residues and Environmental Pollution Department, Central Agricultural Pesticide Laboratory, Agricultural Research Center, Giza, Egypt. FAU - Soliman, Hanim AU - Soliman H AD - Pesticide Residues and Environmental Pollution Department, Central Agricultural Pesticide Laboratory, Agricultural Research Center, Giza, Egypt. FAU - El-Hefny, Dalia AU - El-Hefny D AD - Pesticide Residues and Environmental Pollution Department, Central Agricultural Pesticide Laboratory, Agricultural Research Center, Giza, Egypt. LA - eng PT - Journal Article DEP - 20220831 PL - Switzerland TA - Front Nutr JT - Frontiers in nutrition JID - 101642264 PMC - PMC9470998 OTO - NOTNLM OT - citrus OT - dissipation kinetics OT - eggplants OT - guava OT - residual behavior OT - risk assessment COIS- The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. EDAT- 2022/09/20 06:00 MHDA- 2022/09/20 06:01 PMCR- 2022/01/01 CRDT- 2022/09/19 04:16 PHST- 2022/05/08 00:00 [received] PHST- 2022/07/25 00:00 [accepted] PHST- 2022/09/19 04:16 [entrez] PHST- 2022/09/20 06:00 [pubmed] PHST- 2022/09/20 06:01 [medline] PHST- 2022/01/01 00:00 [pmc-release] AID - 10.3389/fnut.2022.939012 [doi] PST - epublish SO - Front Nutr. 2022 Aug 31;9:939012. doi: 10.3389/fnut.2022.939012. eCollection 2022.