PMID- 36119785
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220920
IS  - 2434-9194 (Electronic)
IS  - 2434-9186 (Print)
IS  - 2434-9186 (Linking)
VI  - 4
IP  - 4
DP  - 2022 Aug 31
TI  - A novel anticoagulation treatment protocol using unfractionated heparin for 
      coronavirus disease 2019 patients in Japan, 2022.
PG  - 233-236
LID - 10.35772/ghm.2022.01030 [doi]
AB  - Hypercoagulability, which can be induced by infection with severe acute 
      respiratory syndrome coronavirus 2 (SARS-CoV-2) plays an important role in the 
      pathogenesis of coronavirus disease 2019 (COVID-19). Although anticoagulation 
      therapy is expected to decrease the incidence of thrombosis and mortality in 
      COVID-19 patients, the optimal use of anticoagulation therapy has not been 
      established, especially using unfractionated heparin (UFH). Herein, we suggest a 
      new anticoagulation treatment protocol for the use of UFH in Japanese COVID-19 
      patients. This protocol considers the safety regarding UFH usage, to lower major 
      bleeding events, and reflects the latest evidence and the current situation 
      regarding anticoagulation therapy in Japan.
CI  - 2022, National Center for Global Health and Medicine.
FAU - Sato, Lubna
AU  - Sato L
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
AD  - Department of Emergency and Critical Care Medicine, Fukushima Medical University, 
      Fukushima, Japan.
FAU - Ishikane, Masahiro
AU  - Ishikane M
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Okumura, Nobumasa
AU  - Okumura N
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Iwamoto, Noriko
AU  - Iwamoto N
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Hayakawa, Kayoko
AU  - Hayakawa K
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
FAU - Iseki, Ken
AU  - Iseki K
AD  - Department of Emergency and Critical Care Medicine, Fukushima Medical University, 
      Fukushima, Japan.
FAU - Hara, Hisao
AU  - Hara H
AD  - Department of Cardiology, National Center for Global Health and Medicine, Tokyo, 
      Japan.
FAU - Ohmagari, Norio
AU  - Ohmagari N
AD  - Disease Control and Prevention Center, National Center for Global Health and 
      Medicine, Tokyo, Japan.
LA  - eng
PT  - Journal Article
PL  - Japan
TA  - Glob Health Med
JT  - Global health & medicine
JID - 101771579
PMC - PMC9420327
OTO - NOTNLM
OT  - SARS-CoV-2
OT  - hypercoagulability
OT  - thrombosis
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2022/09/20 06:00
MHDA- 2022/09/20 06:01
PMCR- 2022/08/31
CRDT- 2022/09/19 04:32
PHST- 2022/03/25 00:00 [received]
PHST- 2022/06/30 00:00 [revised]
PHST- 2022/07/29 00:00 [accepted]
PHST- 2022/09/19 04:32 [entrez]
PHST- 2022/09/20 06:00 [pubmed]
PHST- 2022/09/20 06:01 [medline]
PHST- 2022/08/31 00:00 [pmc-release]
AID - 10.35772/ghm.2022.01030 [doi]
PST - ppublish
SO  - Glob Health Med. 2022 Aug 31;4(4):233-236. doi: 10.35772/ghm.2022.01030.