PMID- 36120215
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220920
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 8
DP  - 2022 Aug
TI  - Liposarcoma: A 'Beer Belly' in Disguise.
PG  - e28067
LID - 10.7759/cureus.28067 [doi]
LID - e28067
AB  - Liposarcoma is a locally aggressive tumor that may originate in soft tissue sites 
      such as the retroperitoneum or the extremities, or less frequently, from the 
      bone. The fatty tumor may have an insidious growth pattern and be present 
      incidentally on imaging, or it may be present with symptoms such as small bowel 
      or ureter obstruction. The diagnosis can be confirmed post-operatively via 
      fluorescence in situ hybridization (FISH) with the presence of mouse double 
      minute 2 (MDM2) homolog protein and cyclin-dependent kinase 4 (CDK4) gene 
      amplification. The rate of recurrence may be high depending on the subtype of 
      liposarcoma, so it is always recommended to have the patient undergo routine 
      imaging every six months to a year. In this case report, we present a patient who 
      presented with a massive, incidental liposarcoma found on imaging after coming to 
      the emergency department for lower extremity trauma.
CI  - Copyright (c) 2022, Luke et al.
FAU - Luke, Nicholas D
AU  - Luke ND
AD  - School of Medicine, St. George's University School of Medicine, True Blue, GRD.
FAU - Gart, Alexander
AU  - Gart A
AD  - Department of Surgery, New York City Health and Hospitals Corporation (NYCHHC), 
      Bronx, USA.
FAU - Mohammad, Raji
AU  - Mohammad R
AD  - Department of Pathology, New York City Health and Hospitals Corporation (NYCHHC), 
      Bronx, USA.
FAU - Raza, Ali
AU  - Raza A
AD  - Department of Surgical Oncology, New York City Health and Hospitals Corporation 
      (NYCHHC), Bronx, USA.
LA  - eng
PT  - Case Reports
DEP - 20220816
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9477226
OTO - NOTNLM
OT  - mdm2
OT  - retroperitoneum
OT  - surgical oncology
OT  - ureter compression
OT  - well differentiated liposarcoma
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/09/20 06:00
MHDA- 2022/09/20 06:01
PMCR- 2022/08/16
CRDT- 2022/09/19 04:38
PHST- 2022/08/16 00:00 [accepted]
PHST- 2022/09/19 04:38 [entrez]
PHST- 2022/09/20 06:00 [pubmed]
PHST- 2022/09/20 06:01 [medline]
PHST- 2022/08/16 00:00 [pmc-release]
AID - 10.7759/cureus.28067 [doi]
PST - epublish
SO  - Cureus. 2022 Aug 16;14(8):e28067. doi: 10.7759/cureus.28067. eCollection 2022 
      Aug.