PMID- 36124231
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221019
IS  - 1868-8527 (Print)
IS  - 1868-8535 (Electronic)
IS  - 1868-8527 (Linking)
VI  - 13
IP  - 10
DP  - 2022
TI  - Mindfulness-Oriented Recovery Enhancement for Addictive Behavior, Psychiatric 
      Distress, and Chronic Pain: A Multilevel Meta-Analysis of Randomized Controlled 
      Trials.
PG  - 2396-2412
LID - 10.1007/s12671-022-01964-x [doi]
AB  - OBJECTIVES: Mindfulness-Oriented Recovery Enhancement (MORE) is an integrative 
      intervention designed to ameliorate addiction, chronic pain, and psychiatric 
      symptoms. Although multiple randomized controlled trials (RCTs) have examined the 
      clinical efficacy of MORE, no study has quantitatively synthesized this body of 
      research. Thus, we conducted a meta-analysis of RCTs examining the effects of 
      MORE on addictive behaviors, craving, opioid dose, pain, and psychiatric 
      symptoms. METHODS: Relevant manuscripts were identified through comprehensive 
      searches of four bibliographic databases. Two- and three-level random-effects 
      models were used to generate synthesized effect size estimates, and 
      meta-regressions were performed to examine whether study and sample 
      characteristics influenced the magnitude of aggregate effect sizes. RESULTS: Our 
      search identified 16 manuscripts reporting data from eight RCTs (N = 816). 
      Moderate to small effects in favor of MORE were observed for addictive behaviors 
      (SMC =  - .54, p = .007), craving (SMC =  - .42, p = .010), opioid dose 
      (MC =  - 17.95, p < .001), chronic pain (SMC =  - .60, p < .001), and psychiatric 
      symptoms (SMC =  - .34, p < .001). MORE's effects on psychiatric symptoms and 
      craving were not moderated by participant race, gender, age, or income. 
      CONCLUSIONS: Study findings provide empirical evidence of MORE's efficacy for a 
      wide diversity of individuals, and as such, MORE should now be disseminated 
      broadly throughout the healthcare system. SUPPLEMENTARY INFORMATION: The online 
      version contains supplementary material available at 10.1007/s12671-022-01964-x.
CI  - (c) The Author(s), under exclusive licence to Springer Science+Business Media, LLC, 
      part of Springer Nature 2022, Springer Nature or its licensor holds exclusive 
      rights to this article under a publishing agreement with the author(s) or other 
      rightsholder(s); author self-archiving of the accepted manuscript version of this 
      article is solely governed by the terms of such publishing agreement and 
      applicable law.
FAU - Parisi, Anna
AU  - Parisi A
AD  - Center On Mindfulness and Integrative Health Intervention Development, University 
      of Utah, 395 South, 1500 East, Salt Lake City, UT 84112 USA. GRID: grid.223827.e. 
      ISNI: 0000 0001 2193 0096
FAU - Roberts, R Lynae
AU  - Roberts RL
AD  - Center On Mindfulness and Integrative Health Intervention Development, University 
      of Utah, 395 South, 1500 East, Salt Lake City, UT 84112 USA. GRID: grid.223827.e. 
      ISNI: 0000 0001 2193 0096
FAU - Hanley, Adam W
AU  - Hanley AW
AD  - Center On Mindfulness and Integrative Health Intervention Development, University 
      of Utah, 395 South, 1500 East, Salt Lake City, UT 84112 USA. GRID: grid.223827.e. 
      ISNI: 0000 0001 2193 0096
FAU - Garland, Eric L
AU  - Garland EL
AD  - Center On Mindfulness and Integrative Health Intervention Development, University 
      of Utah, 395 South, 1500 East, Salt Lake City, UT 84112 USA. GRID: grid.223827.e. 
      ISNI: 0000 0001 2193 0096
AD  - Veterans Health Care Administration VISN 19 Whole Health Flagship Site Located at 
      the VA Salt Lake City Health Care System, Salt Lake City, UT USA. GRID: 
      grid.280807.5. ISNI: 0000 0000 9555 3716
LA  - eng
PT  - Journal Article
DEP - 20220915
PL  - United States
TA  - Mindfulness (N Y)
JT  - Mindfulness
JID - 101518348
PMC - PMC9476401
OTO - NOTNLM
OT  - Addiction
OT  - Chronic pain
OT  - Mental health
OT  - Mindfulness
OT  - Opioids
OT  - Substance use disorders
COIS- Competing InterestsEric Garland, PhD, LCSW, is the Director of the Center on 
      Mindfulness and Integrative Health Intervention Development. The Center provides 
      Mindfulness-Oriented Recovery Enhancement (MORE), mindfulness-based therapy, and 
      cognitive behavioral therapy in the context of research trials for no cost to 
      research participants; however, Dr. Garland has received honoraria and payment 
      for delivering seminars, lectures, and teaching engagements (related to training 
      clinicians in MORE and mindfulness) sponsored by institutions of higher 
      education, government agencies, academic teaching hospitals, and medical centers. 
      Dr. Garland also receives royalties from the sale of books related to MORE. Dr. 
      Garland is also a consultant and licensor to BehaVR, LLC.
EDAT- 2022/09/21 06:00
MHDA- 2022/09/21 06:01
PMCR- 2022/09/15
CRDT- 2022/09/20 02:00
PHST- 2022/08/12 00:00 [accepted]
PHST- 2022/09/21 06:00 [pubmed]
PHST- 2022/09/21 06:01 [medline]
PHST- 2022/09/20 02:00 [entrez]
PHST- 2022/09/15 00:00 [pmc-release]
AID - 1964 [pii]
AID - 10.1007/s12671-022-01964-x [doi]
PST - ppublish
SO  - Mindfulness (N Y). 2022;13(10):2396-2412. doi: 10.1007/s12671-022-01964-x. Epub 
      2022 Sep 15.