PMID- 36126588
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221225
IS  - 2050-1161 (Print)
IS  - 2050-1161 (Electronic)
IS  - 2050-1161 (Linking)
VI  - 10
IP  - 6
DP  - 2022 Dec
TI  - Analysis of the Factors Associated With ED in Type 2 Diabetics at the University 
      Hospital of Libreville.
PG  - 100564
LID - S2050-1161(22)00079-4 [pii]
LID - 10.1016/j.esxm.2022.100564 [doi]
LID - 100564
AB  - INTRODUCTION: Erectile dysfunction (ED) is very common in diabetic males, 
      especially type 2 diabetes mellitus (T2DM). Many factors and complications of 
      diabetes such as macro- and micro-angiopathy are associated with risks leading to 
      ED in male patients. AIM: Analysis of factors associated with ED in T2DM. The 
      purpose of this study is to shed light on potential associations between ED, type 
      2 diabetes, and some risks factors. MATERIAL AND METHODS: This was a prospective 
      analytic study of T2DM over 18. The study population consisted of diabetic 
      patients seen at the endocrinology and urology departments of the University 
      Hospital during the study period. Evaluation of ED was made by IIEF 5 score. 
      OUTCOMES: A total of 333 patients were selected for the study. The mean age was 
      56.6 +/- 9.8 and the prevalence of ED was 82.6% (n = 275). RESULTS: In univariate 
      analysis, several associated factors were identified such as micro-angiopathic 
      type complications including diabetic retinopathy (OR 4.88 [2.31-10.33], P < 
      .001), diabetic nephropathy (OR 12.67 [1.71-93.66], P = .002) and 
      macro-angiopathic type including arterial hypertension (OR 3.12 [1.69-5.75], P < 
      .001). In multivariate analysis, duration of diabetes, micro and macroangiopathic 
      complications, and hyperuricemia were independent risk factors for the occurrence 
      of ED (P < .05). CLINICAL IMPLICATIONS: The presence of certain complications of 
      diabetes such as micro or macro angiopathy or hyperuricemia should lead to a 
      search for a ED. The presence of these associated factors identified in type 2 
      diabetic patients should systematically prompt an ED diagnosis which is often 
      moderate or severe. That diagnosis would help design a protocol for the 
      management and improvement of the life quality of these patients. STRENGTHS AND 
      LIMITATIONS: The strength of this work is that it was conducted in the biggest 
      hospital in the country which gives us a good idea of the trend of this ailment 
      in the country. But the limitation of the study is that it only included patients 
      who visited the hospital. This is monocentric hospital study was also transversal 
      which does allow to establish a causal link. CONCLUSION: ED has a significant 
      prevalence in T2DM. Several associated factors identified in uni and multivariate 
      analyses, including duration of diabetes, micro and macro angiopathic 
      complications, and hyperuricemia, increase ED risk. Therefore, it is essential to 
      investigate the existence of these factors to improve the management of ED, which 
      may allow the patient to regain a better overall health status. SNN Milama, A 
      Mougougou, S G Olagui, et al. Analysis of the Factors Associated With ED in Type 
      2 Diabetics at the University Hospital of Libreville. Sex Med 2022;10:100564.
CI  - Copyright (c) 2022 International Society for Sexual Medicine. Published by Elsevier 
      Inc. All rights reserved.
FAU - Ndang Ngou Milama, Steevy
AU  - Ndang Ngou Milama S
AD  - Urology department at CHU de Libreville, Libreville, Gabon; Department of Surgery 
      at Universite des Sciences de la Sante (USS), Libreville, Gabon. Electronic 
      address: nnmsteevy@gmail.com.
FAU - Mougougou, Adrien
AU  - Mougougou A
AD  - Urology department at CHU de Libreville, Libreville, Gabon; Department of Surgery 
      at Universite des Sciences de la Sante (USS), Libreville, Gabon.
FAU - Olagui, Smith Giscard
AU  - Olagui SG
AD  - Department of General and Urological Surgery, Omar Bongo Ondimba Army Training 
      Hospital, Libreville-Gabon.
FAU - Mbethe, Dimitri
AU  - Mbethe D
AD  - Urology department at CHU de Libreville, Libreville, Gabon.
FAU - Nsame, Daniella
AU  - Nsame D
AD  - DEBIM/UREMCSE, Faculte de Medecine, Universite des Sciences de la Sante (USS), 
      Owendo, Gabon.
FAU - Boundama, Herman Gael
AU  - Boundama HG
AD  - Urology department at CHU de Libreville, Libreville, Gabon.
FAU - Ngoungou, Brice Edgard
AU  - Ngoungou BE
AD  - DEBIM/UREMCSE, Faculte de Medecine, Universite des Sciences de la Sante (USS), 
      Owendo, Gabon; CEBIMER-Gabon, Institut Superieur de Biologie Medicale (ISBM), 
      Universite des Sciences de la Sante (USS), Owendo, Gabon; Inserm U1094, IRD U270, 
      Univ. Limoges, CHU Limoges, EpiMaCT - Epidemiology of chronic diseases in 
      tropical zone, Institute of Epidemiology and Tropical Neurology, OmegaHealth, 
      Limoges, France.
LA  - eng
PT  - Journal Article
DEP - 20220917
PL  - England
TA  - Sex Med
JT  - Sexual medicine
JID - 101631053
PMC - PMC9780774
OTO - NOTNLM
OT  - Associated factors
OT  - Erectile dysfunction
OT  - Type 2 diabetes mellitus
EDAT- 2022/09/21 06:00
MHDA- 2022/09/21 06:01
PMCR- 2022/09/17
CRDT- 2022/09/20 18:27
PHST- 2022/04/04 00:00 [received]
PHST- 2022/07/20 00:00 [revised]
PHST- 2022/08/02 00:00 [accepted]
PHST- 2022/09/21 06:00 [pubmed]
PHST- 2022/09/21 06:01 [medline]
PHST- 2022/09/20 18:27 [entrez]
PHST- 2022/09/17 00:00 [pmc-release]
AID - S2050-1161(22)00079-4 [pii]
AID - 100564 [pii]
AID - 10.1016/j.esxm.2022.100564 [doi]
PST - ppublish
SO  - Sex Med. 2022 Dec;10(6):100564. doi: 10.1016/j.esxm.2022.100564. Epub 2022 Sep 
      17.