PMID- 36127004 OWN - NLM STAT- MEDLINE DCOM- 20220923 LR - 20220923 IS - 1873-4324 (Electronic) IS - 0003-2670 (Linking) VI - 1228 DP - 2022 Oct 2 TI - Solvent-dependent carbon dots for multifunctional sensing of temperature, pH, and proton pump inhibitors. PG - 340341 LID - S0003-2670(22)00912-6 [pii] LID - 10.1016/j.aca.2022.340341 [doi] AB - Multifunctional sensing, a strategy to improve the efficiency of analysis and detection, has attracted much attention. In this study, a multifunction sensing platform was developed for temperature, pH, and proton pump inhibitors (PPI) with fluorescence carbon dots. Solvent-dependent carbon dots (PG-CDs) were synthesized through a one-step solvothermal method from phloroglucinol with the assistance of HCl. Base on the effect of functional groups on the surface, solvent-dependent behavior, temperature and pH responsive fluorescence can be observed. The PG-CDs display a reversible temperature-sensitive fluorescent behavior within 15-65 degrees C in N, N-dimethylacetamide. The fluorescence intensity of PG-CDs also responded to pH in a range of 3.0-7.0 with good reversibility and anti-interference. Therefore, the platform for temperature and pH sensing was proposed. In addition, since the synergistic effect of dynamic and static quenching, proton pump inhibitors (PPI) can be detected sensitively, including esomeprazole (EPZ), omeprazole (OPZ), and rabeprazole (RPZ). The linear range of detection for EPZ, OPZ, and RPZ is 2.0-80.0, 2.0-75.0, and 10.0-200.0 muM and the limits of detection is 0.29, 0.55, and 2.99 muM, separately. The recoveries for real samples were between 91.83 and 102.3%, which indicated that the platform for PPI sensing had good accuracy. CI - Copyright (c) 2022 Elsevier B.V. All rights reserved. FAU - Chen, Piao AU - Chen P AD - School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. FAU - Peng, Jingdong AU - Peng J AD - School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. Electronic address: hxpengjd@swu.edu.cn. FAU - Zhang, Zilong AU - Zhang Z AD - School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. FAU - Wang, Xiang AU - Wang X AD - School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. FAU - Zhu, Xiaolan AU - Zhu X AD - School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. FAU - Fan, Kun AU - Fan K AD - School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. FAU - Luo, Pan AU - Luo P AD - School of Chemistry and Chemical Engineering, Southwest University, Chongqing, 400715, PR China. LA - eng PT - Journal Article DEP - 20220905 PL - Netherlands TA - Anal Chim Acta JT - Analytica chimica acta JID - 0370534 RN - 0 (Proton Pump Inhibitors) RN - 0 (Solvents) RN - 32828355LL (Rabeprazole) RN - 7440-44-0 (Carbon) RN - DHD7FFG6YS (Phloroglucinol) RN - KG60484QX9 (Omeprazole) RN - N3PA6559FT (Esomeprazole) SB - IM MH - *Carbon MH - Esomeprazole MH - Hydrogen-Ion Concentration MH - Omeprazole MH - Phloroglucinol MH - Proton Pump Inhibitors MH - *Quantum Dots MH - Rabeprazole MH - Solvents MH - Temperature OTO - NOTNLM OT - Carbon dots OT - Multifunctional sensing OT - Proton pump inhibitors OT - Solvent-dependent OT - Temperature OT - pH COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2022/09/21 06:00 MHDA- 2022/09/24 06:00 CRDT- 2022/09/20 21:02 PHST- 2022/06/05 00:00 [received] PHST- 2022/08/29 00:00 [revised] PHST- 2022/08/31 00:00 [accepted] PHST- 2022/09/20 21:02 [entrez] PHST- 2022/09/21 06:00 [pubmed] PHST- 2022/09/24 06:00 [medline] AID - S0003-2670(22)00912-6 [pii] AID - 10.1016/j.aca.2022.340341 [doi] PST - ppublish SO - Anal Chim Acta. 2022 Oct 2;1228:340341. doi: 10.1016/j.aca.2022.340341. Epub 2022 Sep 5.