PMID- 36128059
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220922
IS  - 1178-7007 (Print)
IS  - 1178-7007 (Electronic)
IS  - 1178-7007 (Linking)
VI  - 15
DP  - 2022
TI  - Association Between Hemoglobin Levels and Osteoporosis in Chinese Patients with 
      Type 2 Diabetes Mellitus: A Cross-Sectional Study.
PG  - 2803-2811
LID - 10.2147/DMSO.S382480 [doi]
AB  - PURPOSE: To explore the relationship between hemoglobin levels and osteoporosis 
      and the risk factors for osteoporosis in patients with type 2 diabetes mellitus 
      (T2DM). PATIENTS AND METHODS: A cross-sectional study was conducted in 495 T2DM 
      adults. Medical data were collected from electronic medical records. RESULTS: 
      T2DM patients with osteoporosis had significant lower hemoglobin levels (P < 
      0.001). Spearman correlation analysis and logistic regression analysis showed 
      that age, female, body mass index (BMI), smoking, drinking and hemoglobin levels 
      were significantly associated with osteoporosis in T2DM patients (all P < 0.05). 
      After adjustment for BMI, diabetic duration, estimated glomerular filtration rate 
      (eGFR), smoking and drinking, a significant association between hemoglobin levels 
      and osteoporosis was observed in T2DM males aged 50 years and older (odds ratio 
      [OR] = 0.978, 95% confidence interval [CI]: 0.958-0.998, P = 0.030). Compared to 
      Q3 groups with normal hemoglobin levels, Q1 groups with anemia had an odd of 
      osteoporosis increased 2.9-fold in T2DM men after adjustment for age, BMI, 
      diabetic duration, eGFR, smoking and drinking (P = 0.032). CONCLUSION: Hemoglobin 
      levels were associated with the presence of osteoporosis in T2DM men, especially 
      in those aged 50 years and older.
CI  - (c) 2022 Ye et al.
FAU - Ye, Tingting
AU  - Ye T
AUID- ORCID: 0000-0002-9026-4311
AD  - Department of Geriatric Endocrinology and Metabolism, The First Affiliated 
      Hospital of Guangxi Medical University, Nanning, People's Republic of China.
FAU - Lu, Liujin
AU  - Lu L
AD  - Department of Geriatric Endocrinology and Metabolism, The First Affiliated 
      Hospital of Guangxi Medical University, Nanning, People's Republic of China.
FAU - Guo, Liuqing
AU  - Guo L
AD  - Department of Geriatric Endocrinology and Metabolism, The First Affiliated 
      Hospital of Guangxi Medical University, Nanning, People's Republic of China.
FAU - Liang, Min
AU  - Liang M
AD  - Department of Geriatric Endocrinology and Metabolism, The First Affiliated 
      Hospital of Guangxi Medical University, Nanning, People's Republic of China.
LA  - eng
PT  - Journal Article
DEP - 20220914
PL  - New Zealand
TA  - Diabetes Metab Syndr Obes
JT  - Diabetes, metabolic syndrome and obesity : targets and therapy
JID - 101515585
PMC - PMC9482778
OTO - NOTNLM
OT  - bone mineral density
OT  - hemoglobin
OT  - osteoporosis
OT  - type 2 diabetes mellitus
COIS- The authors report no conflicts of interest in this work.
EDAT- 2022/09/22 06:00
MHDA- 2022/09/22 06:01
PMCR- 2022/09/14
CRDT- 2022/09/21 01:56
PHST- 2022/07/15 00:00 [received]
PHST- 2022/09/02 00:00 [accepted]
PHST- 2022/09/21 01:56 [entrez]
PHST- 2022/09/22 06:00 [pubmed]
PHST- 2022/09/22 06:01 [medline]
PHST- 2022/09/14 00:00 [pmc-release]
AID - 382480 [pii]
AID - 10.2147/DMSO.S382480 [doi]
PST - epublish
SO  - Diabetes Metab Syndr Obes. 2022 Sep 14;15:2803-2811. doi: 10.2147/DMSO.S382480. 
      eCollection 2022.