PMID- 36129765
OWN - NLM
STAT- MEDLINE
DCOM- 20230310
LR  - 20230310
IS  - 1443-1661 (Electronic)
IS  - 0915-5635 (Linking)
VI  - 35
IP  - 3
DP  - 2023 Mar
TI  - Efficacy of pancreatic duct stenting to prevent postendoscopic retrograde 
      cholangiopancreatography pancreatitis after covered self-expandable metal 
      stent deployment.
PG  - 369-376
LID - 10.1111/den.14442 [doi]
AB  - OBJECTIVES: Although covered self-expandable metal stents (CSEMSs) are associated 
      with the risk of postendoscopic retrograde cholangiopancreatography (ERCP) 
      pancreatitis due to pancreatic duct (PD) orifice obstruction, they are often used 
      for biliary drainage treatment in malignant biliary obstruction (MBO). This study 
      aimed to investigate the efficacy of PD stenting in preventing post-ERCP 
      pancreatitis after CSEMS implantation. METHODS: This retrospective cohort study 
      analyzed 554 patients with transpapillary CSEMS for MBO. Patients with noninitial 
      deployment, benign disease, CSEMS deployment above the papilla, surgically 
      altered anatomy, uncovered self-expandable metal stents, multiple thin 
      self-expandable metal stents, and unavailable procedure videos were excluded. 
      Logistic regression analysis estimated the association between PD stenting and 
      post-ERCP pancreatitis incidence. We adjusted for age, sex, pancreatitis history, 
      prophylactic rectal nonsteroidal anti-inflammatory drug use, naive papilla, MBO 
      etiology, and prolonged biliary cannulation time. RESULTS: Among 554 patients, 67 
      (12.1%) experienced post-ERCP pancreatitis. Post-ERCP pancreatitis was recorded 
      in 13.7% of patients in the non-PD stenting and 4.3% in the PD stenting groups. 
      Pancreatic duct stenting was associated with lower risks of post-ERCP 
      pancreatitis (odds ratio [OR] 0.28; 95% confidence interval [CI] 0.099-0.79; 
      P = 0.028). In multivariable analysis, the association between PD stenting and 
      lower post-ERCP pancreatitis incidence was consistent (OR 0.19; 95% CI 
      0.062-0.58; P = 0.0034). CONCLUSIONS: Pancreatic duct stenting could reduce the 
      risk of post-ERCP pancreatitis after CSEMSs.
CI  - (c) 2022 Japan Gastroenterological Endoscopy Society.
FAU - Toyonaga, Haruka
AU  - Toyonaga H
AUID- ORCID: 0000-0001-7300-3665
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Hayashi, Tsuyoshi
AU  - Hayashi T
AUID- ORCID: 0000-0001-7666-5795
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Yamazaki, Hajime
AU  - Yamazaki H
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
AD  - Section of Clinical Epidemiology, Department of Community Medicine, Graduate 
      School of Medicine, Kyoto University, Kyoto, Japan.
FAU - Hama, Kazuki
AU  - Hama K
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Iwano, Kosuke
AU  - Iwano K
AUID- ORCID: 0000-0002-6207-4684
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Nakamura, Risa
AU  - Nakamura R
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Ando, Ryo
AU  - Ando R
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Shimizu, Takao
AU  - Shimizu T
AUID- ORCID: 0000-0001-5783-3730
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Ishii, Tatsuya
AU  - Ishii T
AUID- ORCID: 0000-0003-2136-4703
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Kin, Toshifumi
AU  - Kin T
AUID- ORCID: 0000-0003-1349-8154
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Takahashi, Kuniyuki
AU  - Takahashi K
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
FAU - Katanuma, Akio
AU  - Katanuma A
AUID- ORCID: 0000-0003-3548-5215
AD  - Center for Gastroenterology, Teine Keijinkai Hospital, Hokkaido, Japan.
LA  - eng
PT  - Journal Article
DEP - 20221022
PL  - Australia
TA  - Dig Endosc
JT  - Digestive endoscopy : official journal of the Japan Gastroenterological Endoscopy 
      Society
JID - 9101419
SB  - IM
MH  - Humans
MH  - Cholangiopancreatography, Endoscopic Retrograde/adverse effects/methods
MH  - Retrospective Studies
MH  - Pancreatic Ducts/surgery
MH  - *Pancreatitis/epidemiology/etiology/prevention & control
MH  - Stents/adverse effects
MH  - *Pancreatic Diseases
OTO - NOTNLM
OT  - covered self-expandable metal stent
OT  - malignant biliary obstruction
OT  - pancreatic duct stenting
OT  - post-ERCP pancreatitis
OT  - tertiary medical center
EDAT- 2022/09/22 06:00
MHDA- 2023/03/11 06:00
CRDT- 2022/09/21 12:03
PHST- 2022/05/15 00:00 [received]
PHST- 2022/09/20 00:00 [accepted]
PHST- 2022/09/22 06:00 [pubmed]
PHST- 2023/03/11 06:00 [medline]
PHST- 2022/09/21 12:03 [entrez]
AID - 10.1111/den.14442 [doi]
PST - ppublish
SO  - Dig Endosc. 2023 Mar;35(3):369-376. doi: 10.1111/den.14442. Epub 2022 Oct 22.