PMID- 36136063 OWN - NLM STAT- MEDLINE DCOM- 20221202 LR - 20221229 IS - 2470-9239 (Electronic) IS - 2470-9239 (Linking) VI - 7 IP - 4 DP - 2022 Dec TI - Epilepsy surgery program in a resource-limited setting in Vietnam: A multicentered collaborative model. PG - 710-717 LID - 10.1002/epi4.12650 [doi] AB - OBJECTIVE: Although epilepsy surgery is more effective than medical therapy for drug-resistant patients, it is underutilized in both high-income and low- and middle-income countries. In light of our efforts to establish an epilepsy surgery program in a resource-limited setting, this study aimed to determine the outcome of the epilepsy surgery program in Ho Chi Minh City (HCMC), Vietnam. METHODS: In 2018, we developed the HCMC epilepsy core multidisciplinary team with members from various hospitals and centers. The team typically included neurologists, neurosurgeons, neuropsychologists, psychiatrists, and nursing specialists. Presurgical evaluations were performed for patients with drug-resistant epilepsy, fulfilling the ILAE criteria, with an epileptogenic lesion (mesial temporal sclerosis, low-grade gliomas, or focal cortical dysplasia). All epilepsy surgeries were performed in two epilepsy surgery centers in HCMC between 2018 and 2021. The patients were followed up for at least 12 months. RESULTS: Fifty-two patients with drug-resistant epilepsy underwent presurgical evaluation, of which 35 underwent surgery. Among the 52 patients, 20 (38.5%) underwent surgery after showing concordance among the results of standard presurgical assessments such as semiology, scalp interictal or ictal electroencephalography, and brain imaging. Among the 26 people with epilepsy who required more advanced evaluations, 15 underwent surgery with intraoperative electrocorticography to delineate the optimal resection borders. The outcomes of Engel Class I and Class II were achieved in 29/35 (82.8%) and 6/35 (17.2%) patients, respectively. SIGNIFICANCE: The epilepsy surgery program with a multicentered collaborative model in a resource-limited setting showed favorable outcomes in HCMC, Vietnam. CI - (c) 2022 The Authors. Epilepsia Open published by Wiley Periodicals LLC on behalf of International League Against Epilepsy. FAU - Le, Viet-Thang AU - Le VT AUID- ORCID: 0000-0002-4702-7214 AD - Department of Neurosurgery, University Medical Center at Ho Chi Minh City, Ho Chi Minh City, Vietnam. AD - Department of Neurosurgery, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. FAU - Thuy Le, Minh-An AU - Thuy Le MA AUID- ORCID: 0000-0001-9658-6453 AD - Department of Neurology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. AD - Department of Neurology, Nguyen Tri Phuong Hospital, Ho Chi Minh City, Vietnam. FAU - Nguyen, Duc Hue AU - Nguyen DH AD - Department of Neurosurgery, Nguyen Tri Phuong Hospital, Ho Chi Minh City, Vietnam. FAU - Tang, Loc Ngoc Phuong AU - Tang LNP AUID- ORCID: 0000-0002-2192-1445 AD - Department of Neurology, Nguyen Tri Phuong Hospital, Ho Chi Minh City, Vietnam. AD - Department of Neurology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam. FAU - Pham, Tuan Anh AU - Pham TA AD - Department of Neurosurgery, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. AD - Department of Neurosurgery, Nguyen Tri Phuong Hospital, Ho Chi Minh City, Vietnam. FAU - Nguyen, Anh Minh AU - Nguyen AM AD - Department of Neurosurgery, University Medical Center at Ho Chi Minh City, Ho Chi Minh City, Vietnam. FAU - Nguyen, Minh Kien AU - Nguyen MK AD - Department of Infection Disease, Children Hospital 1, Ho Chi Minh City, Vietnam. FAU - Van Ngo, Tan AU - Van Ngo T AD - Division of PET-CT and Cyclotron, Nuclear Medicine Department, Cho Ray hospital, Ho Chi Minh City, Vietnam. FAU - Tran, Thanh Trung AU - Tran TT AD - Department of Neurology, Nguyen Tri Phuong Hospital, Ho Chi Minh City, Vietnam. FAU - Van Le, Tuan AU - Van Le T AUID- ORCID: 0000-0002-5885-1479 AD - Department of Neurology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. FAU - Jallon, Pierre AU - Jallon P AD - Department of Neurology, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam. FAU - Lim, Kheng-Seang AU - Lim KS AUID- ORCID: 0000-0002-2787-2365 AD - Division of Neurology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia. LA - eng PT - Journal Article DEP - 20221005 PL - United States TA - Epilepsia Open JT - Epilepsia open JID - 101692036 SB - IM MH - Humans MH - Vietnam MH - *Epilepsy/surgery MH - *Malformations of Cortical Development MH - *Drug Resistant Epilepsy/surgery MH - Electrocorticography PMC - PMC9712473 OTO - NOTNLM OT - drug-resistant OT - epilepsy surgery OT - limited-resource OT - multidisciplinary team COIS- None of the authors has any conflict of interest to disclose. EDAT- 2022/09/23 06:00 MHDA- 2022/12/03 06:00 PMCR- 2022/10/05 CRDT- 2022/09/22 10:52 PHST- 2022/05/17 00:00 [received] PHST- 2022/09/18 00:00 [accepted] PHST- 2022/09/23 06:00 [pubmed] PHST- 2022/12/03 06:00 [medline] PHST- 2022/09/22 10:52 [entrez] PHST- 2022/10/05 00:00 [pmc-release] AID - EPI412650 [pii] AID - 10.1002/epi4.12650 [doi] PST - ppublish SO - Epilepsia Open. 2022 Dec;7(4):710-717. doi: 10.1002/epi4.12650. Epub 2022 Oct 5.