PMID- 36137124
OWN - NLM
STAT- MEDLINE
DCOM- 20220926
LR  - 20220928
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 17
IP  - 9
DP  - 2022
TI  - Unilateral cathodal transcranial direct current stimulation over the parietal 
      area modulates postural control depending with eyes open and closed.
PG  - e0269145
LID - 10.1371/journal.pone.0269145 [doi]
LID - e0269145
AB  - OBJECTIVE: Cathodal transcranial direct current stimulation (C-tDCS) is generally 
      assumed to inhibit cortical excitability. The parietal cortex contributes to 
      multisensory information processing in the postural control system, and this 
      processing is proposed to be different between the right and left hemispheres and 
      sensory modality. However, previous studies did not clarify whether the effects 
      of unilateral C-tDCS of the parietal cortex on the postural control system differ 
      depending on the hemisphere. We investigated the changes in static postural 
      stability after unilateral C-tDCS of the parietal cortex. METHODS: Ten healthy 
      right-handed participants were recruited for right- and left-hemisphere tDCS and 
      sham stimulation, respectively. The cathodal electrode was placed on either the 
      right or left parietal area, whereas the anodal electrode was placed over the 
      contralateral orbit. tDCS was applied at 1.5 mA for 15 min. We evaluated static 
      standing balance by measuring the sway path length (SPL), mediolateral sway path 
      length (ML-SPL), anteroposterior sway path length (AP-SPL), sway area, and the 
      SPL per unit area (L/A) after 15-minute C-tDCS under eyes open (EO) and closed 
      (EC) conditions. To evaluate the effects of C-tDCS on pre- and post-offline 
      trials, each parameter was compared using two-way repeated-measures analysis of 
      variance (ANOVA) with factors of intervention and time. A post-hoc evaluation was 
      performed using a paired t-test. The effect sizes were evaluated according to 
      standardized size-effect indices of partial eta-squared (etap2) and Cohen's d. The 
      power analysis was calculated (1-beta). RESULTS: A significant interaction was 
      observed between intervention and time for SPL (F (2, 27) = 4.740, p = 0.017, etap2 
      = 0.260), ML-SPL (F (2, 27) = 4.926, p = 0.015, etap2 = 0.267), and sway area (F 
      (2, 27) = 9.624, p = 0.001, etap2 = 0.416) in the EO condition. C-tDCS over the 
      right hemisphere significantly increased the SPL (p < 0.01, d = 0.51), ML-SPL (p 
      < 0.01, d = 0.52), and sway area (p < 0.05, d = 0.83) in the EO condition. In 
      contrast, C-tDCS over the left hemisphere significantly increased the L/A in both 
      the EC and EO condition (EO; p < 0.05, d = 0.67, EC; p < 0.05, d = 0.57). 
      CONCLUSION: These results suggest that the right parietal region contributes to 
      static standing balance through chiefly visual information processing during the 
      EO condition. On the other hand, L/A increase during EC and EO by tDCS over the 
      left parietal region depends more on somatosensory information to maintain static 
      standing balance during the EC condition.
FAU - Oka, Shinichiro
AU  - Oka S
AUID- ORCID: 0000-0002-3422-0963
AD  - Faculty of Rehabilitation, Department of Physical Therapy, Reiwa Health Sciences 
      University, Fukuoka, Japan.
FAU - Ikeda, Takuro
AU  - Ikeda T
AD  - Faculty of Medicine Science, Department of Physical Therapy, Fukuoka 
      International University of Health and Welfare, Fukuoka, Japan.
FAU - Mitsutake, Tsubasa
AU  - Mitsutake T
AD  - Faculty of Medicine Science, Department of Physical Therapy, Fukuoka 
      International University of Health and Welfare, Fukuoka, Japan.
FAU - Ogata, Katsuya
AU  - Ogata K
AUID- ORCID: 0000-0002-7559-9615
AD  - Faculty of Pharmacy at Fukuoka, Department of Pharmaceutical Sciences, 
      International University of Health and Welfare, Fukuoka, Japan.
FAU - Goto, Yoshinobu
AU  - Goto Y
AD  - School of Medicine, International University of Health and Welfare, Chiba, Japan.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20220922
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Analysis of Variance
MH  - Electrodes
MH  - Humans
MH  - Parietal Lobe/physiology
MH  - Postural Balance/physiology
MH  - *Transcranial Direct Current Stimulation
PMC - PMC9499265
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/09/23 06:00
MHDA- 2022/09/28 06:00
PMCR- 2022/09/22
CRDT- 2022/09/22 14:24
PHST- 2022/05/13 00:00 [received]
PHST- 2022/09/12 00:00 [accepted]
PHST- 2022/09/22 14:24 [entrez]
PHST- 2022/09/23 06:00 [pubmed]
PHST- 2022/09/28 06:00 [medline]
PHST- 2022/09/22 00:00 [pmc-release]
AID - PONE-D-22-14020 [pii]
AID - 10.1371/journal.pone.0269145 [doi]
PST - epublish
SO  - PLoS One. 2022 Sep 22;17(9):e0269145. doi: 10.1371/journal.pone.0269145. 
      eCollection 2022.