PMID- 36142085 OWN - NLM STAT- MEDLINE DCOM- 20220926 LR - 20230112 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 19 IP - 18 DP - 2022 Sep 19 TI - Development and Validation of the Chinese Frailty Screening Scale: A Study among Community-Dwelling Older Adults in Shanghai. LID - 10.3390/ijerph191811811 [doi] LID - 11811 AB - BACKGROUND: Based on intrinsic capacity (IC) as defined by the World Health Organization, an accelerated decline may be an important precursor of frailty among older adults; however, there is a lack of validated instruments that both screen for frailty and monitor IC. This study aims to develop a comprehensive and acculturative frailty screening scale to determine healthy aging among older Chinese adults. SETTING AND PARTICIPANTS: A cross-sectional and a cohort study both based on community-dwelling older adults aged 65 and older. METHODS: This study mainly consisted of two parts. First, the selection and revision of 20 items related to frailty based on a literature review, expert consultation, and stakeholder analysis; second, a cross-sectional study was conducted to simplify the scale and test the reliability and validity of the new frailty screening tool. The fatigue, resistance, ambulation, illness, and loss of weight (FRAIL) scale, the Tilburg frailty indictor (TFI), and a 49-item Frailty Index (FI) were investigated as criteria. Additionally, a cohort study in Shanghai was conducted to verify the predictive validity of the new screening scale. The disability measured by the activity of daily living (ADL), instrumental activity of daily living (IADL) and all-cause mortality were documented as outcomes. RESULTS: A 10-item Chinese frailty screening scale (CFSS-10) was successfully developed and validated. It presented a Cronbach's alpha of 0.63 and an intraclass correlation coefficient of 0.73, which indicated good reliability. Taking the other frailty tools as criteria, Kappa values of 0.54-0.58 and an area under the curve of 0.87-0.91 showed good validity. The results of the log-binomial and Poisson models showed a high score, which predicted a higher risk of disability and all-cause mortality. An optimal cut-off point of 5 gave an excellent prediction of one-year disability. CONCLUSIONS: The CFSS-10 has good validity and reliability as a quick and acculturative frailty screening scale for community-dwelling older adults in Shanghai. It may also supplement existing frailty screening tools. FAU - Ye, Bo AU - Ye B AUID- ORCID: 0000-0002-4088-5734 AD - Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China. FAU - Wang, Yi AU - Wang Y AD - School of Public Health, Fudan University, Shanghai 200032, China. FAU - Chen, Hao AU - Chen H AD - School of Public Health, Fudan University, Shanghai 200032, China. FAU - Chen, Yingwei AU - Chen Y AD - School of Public Health, Fudan University, Shanghai 200032, China. FAU - Yan, Huihui AU - Yan H AD - School of Public Health, Fudan University, Shanghai 200032, China. FAU - Fu, Hua AU - Fu H AD - School of Public Health, Fudan University, Shanghai 200032, China. AD - Health Communication Institute, Fudan University, Shanghai 200032, China. FAU - Bao, Zhijun AU - Bao Z AD - Huadong Hospital Affiliated to Fudan University, Shanghai 200040, China. AD - Shanghai Key Laboratory of Clinical Geriatric Medicine, Huadong Hospital, Shanghai 200040, China. FAU - Gao, Junling AU - Gao J AUID- ORCID: 0000-0002-0694-2010 AD - School of Public Health, Fudan University, Shanghai 200032, China. AD - Collaborative Innovation Cooperative Unit, National Clinical Research Center for Geriatric Diseases, Shanghai 200032, China. AD - Core Unit, Shanghai Clinical Research Center for Geriatric Diseases, Shanghai 200032, China. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20220919 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - Aged MH - China MH - Cohort Studies MH - Cross-Sectional Studies MH - Frail Elderly MH - *Frailty/diagnosis MH - Geriatric Assessment/methods MH - Humans MH - Independent Living MH - Middle Aged MH - Psychometrics/methods MH - Reproducibility of Results PMC - PMC9517433 OTO - NOTNLM OT - assessment tool OT - disability OT - frailty OT - healthy aging OT - older adults COIS- The authors declare no conflict of interest. EDAT- 2022/09/24 06:00 MHDA- 2022/09/28 06:00 PMCR- 2022/09/19 CRDT- 2022/09/23 01:21 PHST- 2022/07/25 00:00 [received] PHST- 2022/09/15 00:00 [revised] PHST- 2022/09/16 00:00 [accepted] PHST- 2022/09/23 01:21 [entrez] PHST- 2022/09/24 06:00 [pubmed] PHST- 2022/09/28 06:00 [medline] PHST- 2022/09/19 00:00 [pmc-release] AID - ijerph191811811 [pii] AID - ijerph-19-11811 [pii] AID - 10.3390/ijerph191811811 [doi] PST - epublish SO - Int J Environ Res Public Health. 2022 Sep 19;19(18):11811. doi: 10.3390/ijerph191811811.