PMID- 36144021 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230308 IS - 2072-666X (Print) IS - 2072-666X (Electronic) IS - 2072-666X (Linking) VI - 13 IP - 9 DP - 2022 Aug 26 TI - Prediction Model for Liquid-Assisted Femtosecond Laser Micro Milling of Quartz without Taper. LID - 10.3390/mi13091398 [doi] LID - 1398 AB - The strong nonlinear absorption effect and "cold" processing characteristics of femtosecond lasers make them uniquely advantageous and promising for the micro- and nanoprocessing of hard and brittle materials, such as quartz. Traditional methods for studying the effects of femtosecond laser parameters on the quality of the processed structure mainly use univariate analysis methods, which require large mounts of experiments to predict and achieve the desired experimental results. The method of design of experiments (DOE) provides a way to predict desirable experimental results through smaller experimental scales, shorter experimental periods and lower experimental costs. In this study, a DOE program was designed to investigate the effects of a serious of parameters (laser repetition frequency, pulse energy, scan speed, scan distance, scan mode, scan times and laser focus position) on the depth and roughness (Ra) of the fabricated structure through the liquid-assisted femtosecond laser processing of quartz. A prediction model between the response variables and the main parameters was defined and validated. Finally, several blind holes with a size of 50 x 50 mum2 and a depth of 200 mum were fabricated by the prediction model, which demonstrated the good consistency of the prediction model. FAU - Yuan, Hongbing AU - Yuan H AD - Faculty of Mechanical Engineering & Mechanics, Ningbo University, Ningbo 315211, China. AD - Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, Ningbo 315201, China. FAU - Chen, Zhihao AU - Chen Z AD - Faculty of Mechanical Engineering & Mechanics, Ningbo University, Ningbo 315211, China. AD - Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, Ningbo 315201, China. FAU - Wu, Peichao AU - Wu P AD - Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, Ningbo 315201, China. AD - University of Chinese Academy of Sciences, Beijing 100049, China. FAU - Deng, Yimin AU - Deng Y AD - Faculty of Mechanical Engineering & Mechanics, Ningbo University, Ningbo 315211, China. FAU - Cao, Xiaowen AU - Cao X AD - Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, Ningbo 315201, China. FAU - Zhang, Wenwu AU - Zhang W AD - Ningbo Institute of Materials Technology & Engineering, Chinese Academy of Sciences, Ningbo 315201, China. LA - eng PT - Journal Article DEP - 20220826 PL - Switzerland TA - Micromachines (Basel) JT - Micromachines JID - 101640903 PMC - PMC9503145 OTO - NOTNLM OT - design of experiment (DOE) OT - femtosecond laser OT - liquid assisted OT - prediction model COIS- The authors declare no conflict of interest. EDAT- 2022/09/24 06:00 MHDA- 2022/09/24 06:01 PMCR- 2022/08/26 CRDT- 2022/09/23 01:33 PHST- 2022/07/20 00:00 [received] PHST- 2022/08/20 00:00 [revised] PHST- 2022/08/22 00:00 [accepted] PHST- 2022/09/23 01:33 [entrez] PHST- 2022/09/24 06:00 [pubmed] PHST- 2022/09/24 06:01 [medline] PHST- 2022/08/26 00:00 [pmc-release] AID - mi13091398 [pii] AID - micromachines-13-01398 [pii] AID - 10.3390/mi13091398 [doi] PST - epublish SO - Micromachines (Basel). 2022 Aug 26;13(9):1398. doi: 10.3390/mi13091398.