PMID- 3615536
OWN - NLM
STAT- MEDLINE
DCOM- 19870828
LR  - 20190712
IS  - 0091-3057 (Print)
IS  - 0091-3057 (Linking)
VI  - 27
IP  - 1
DP  - 1987 May
TI  - Effects of acute nicotine and ethanol on medial prefrontal cortex 
      self-stimulation in rats.
PG  - 15-20
AB  - The acute effects of nicotine and ethanol were studied in low and high rates of 
      intracranial self-stimulation (ICSS) of the medial prefrontal cortex (MPFC) in 
      the rat. Nicotine tended to increase low ICSS rates but did not change or even 
      reduced high ICSS rates. Independent of ICSS rate, ethanol tended to decrease 
      ICSS, but only at high doses (1.0 g/kg). It is suggested that the effects of 
      nicotine and ethanol on ICSS may be mediated by their effects on dopamine.
FAU - Arregui-Aguirre, A
AU  - Arregui-Aguirre A
FAU - Claro-Izaguirre, F
AU  - Claro-Izaguirre F
FAU - Goni-Garrido, M J
AU  - Goni-Garrido MJ
FAU - Zarate-Oleaga, J A
AU  - Zarate-Oleaga JA
FAU - Morgado-Bernal, I
AU  - Morgado-Bernal I
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - United States
TA  - Pharmacol Biochem Behav
JT  - Pharmacology, biochemistry, and behavior
JID - 0367050
RN  - 3K9958V90M (Ethanol)
RN  - 6M3C89ZY6R (Nicotine)
SB  - IM
MH  - Animals
MH  - Dose-Response Relationship, Drug
MH  - Ethanol/*pharmacology
MH  - Frontal Lobe/*physiology
MH  - Male
MH  - Nicotine/*pharmacology
MH  - Rats
MH  - Rats, Inbred Strains
MH  - Self Stimulation/*drug effects
EDAT- 1987/05/01 00:00
MHDA- 1987/05/01 00:01
CRDT- 1987/05/01 00:00
PHST- 1987/05/01 00:00 [pubmed]
PHST- 1987/05/01 00:01 [medline]
PHST- 1987/05/01 00:00 [entrez]
AID - 0091-3057(87)90470-9 [pii]
AID - 10.1016/0091-3057(87)90470-9 [doi]
PST - ppublish
SO  - Pharmacol Biochem Behav. 1987 May;27(1):15-20. doi: 10.1016/0091-3057(87)90470-9.