PMID- 36156482
OWN - NLM
STAT- MEDLINE
DCOM- 20220928
LR  - 20220928
IS  - 0125-9326 (Print)
IS  - 0125-9326 (Linking)
VI  - 54
IP  - 3
DP  - 2022 Jul
TI  - Acute Limb Ischemia due to Arterial Thrombosis in a Patient with COVID-19 
      Pneumonia: A Case Report.
PG  - 438-443
AB  - The COVID-19 pandemic has caused more than 4 million deaths worldwide to date. 
      During the course of the COVID-19 pandemic, thrombotic complications due to 
      hypercoagulable state have emerged as an important issue. Acute limb ischemia is 
      one of emergency cases in vascular disease caused by a sudden decrease in 
      arterial limbs perfusion. Here, we report a 53-year-old male patient with severe 
      COVID-19 and a history of uncontrolled type 2 diabetes mellitus (T2DM) who 
      developed extensive arterial thrombosis and limb ischemia despite being on 
      therapeutic-dose anticoagulation, requiring surgical intervention. Right and left 
      leg open thrombectomy was performed at day 7 after admission due to the 
      excruciating pain and the worsening of the limb conditions. The patient was 
      transferred to intensive care unit in emergency room because of the unstable 
      hemodynamic and passed away a few hours after the surgery. For critically ill 
      patients with COVID-19, special attention should be paid to abnormal coagulation 
      dysfunction and microcirculatory disorders.
FAU - Primasari, Renata
AU  - Primasari R
AD  - Clinical Pathology Specialization Program, Faculty of Medicine Universitas 
      Airlangga, Surabaya, Indonesia. primasarirenata@gmail.com.
FAU - Hernaningsih, Yetti
AU  - Hernaningsih Y
FAU - Kahar, Hartono
AU  - Kahar H
FAU - Bramantono, Bramantono
AU  - Bramantono B
LA  - eng
PT  - Case Reports
PT  - Journal Article
PL  - Indonesia
TA  - Acta Med Indones
JT  - Acta medica Indonesiana
JID - 7901042
RN  - 0 (Anticoagulants)
SB  - IM
MH  - Anticoagulants/therapeutic use
MH  - *COVID-19/complications
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Humans
MH  - Ischemia/etiology/surgery
MH  - Male
MH  - Microcirculation
MH  - Middle Aged
MH  - Pandemics
MH  - *Thrombosis/etiology
OTO - NOTNLM
OT  - ALI
OT  - COVID-19
OT  - acute limb ischemia
OT  - hypercoagulable state
EDAT- 2022/09/27 06:00
MHDA- 2022/09/28 06:00
CRDT- 2022/09/26 16:40
PHST- 2022/09/26 16:40 [entrez]
PHST- 2022/09/27 06:00 [pubmed]
PHST- 2022/09/28 06:00 [medline]
PST - ppublish
SO  - Acta Med Indones. 2022 Jul;54(3):438-443.