PMID- 36157037
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220928
IS  - 2296-2646 (Print)
IS  - 2296-2646 (Electronic)
IS  - 2296-2646 (Linking)
VI  - 10
DP  - 2022
TI  - Nanochannel array modified three-dimensional graphene electrode for sensitive 
      electrochemical detection of 2,4,6-trichlorophenol and prochloraz.
PG  - 954802
LID - 10.3389/fchem.2022.954802 [doi]
LID - 954802
AB  - Convenient, and sensitive detection of pesticides and their metabolites in 
      environmental or food samples is critical for assessing potential environmental 
      and health risks. Here, a three-dimensional (3D) electrochemical sensing platform 
      is proposed based on the integration of nanochannel array on pre-activated 3D 
      graphene (p-3DG) electrodes with no need of additional adhesive layers, which 
      enables sensitive detection of prochloraz and 2,4,6-trichlorophenol (TCP) in 
      environmental and food samples. Through two-step electrochemical polarization, 
      organic phase anodic oxidation, and aqueous phase cathodic reduction, p-3DG 
      electrodes with high active area and excellent electrocatalytic performance were 
      obtained. Vertically-ordered mesoporous silica-nanochannel film (VMSF) can be 
      rapidly grown on the surface of p-3DG by an electrochemical-assisted 
      self-assembly (EASA) method. Taking advantage of the high electrocatalytic 
      activity of p-3DG and the ability of nanochannels to enrich TCP through hydrogen 
      bonding, the VMSF/p-3DG sensor can sensitively detect TCP in the range of 10 nM 
      to 0.1 muM and 0.1-15 muM with a low limit of detection (LOD) of 2.4 nM. Compared 
      with p-3DG and VMSF-modified 2D electrodes, the fabricated sensor has a wide 
      detection linear range and low LOD. The coexistence of model interferents such as 
      protein, surfactant, and humic acid did not affect the electrochemical response 
      of TCP, confirming the high anti-fouling ability of the VMSF/p-3DG sensor. In 
      addition, prochloraz in vegetable and fruit samples was indirectly determined 
      because TCP was the metabolite of prochloraz.
CI  - Copyright (c) 2022 Zheng, Su, Lin and Liu.
FAU - Zheng, Weiran
AU  - Zheng W
AD  - Institute of Agro-product Safety and Nutrition, Zhejiang Academy of Agricultural 
      Sciences, Hangzhou, China.
FAU - Su, Ruobing
AU  - Su R
AD  - Department of Chemistry, Key Laboratory of Surface and Interface Science of 
      Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, 
      China.
FAU - Lin, Xingyu
AU  - Lin X
AD  - College of Biosystems Engineering and Food Science, Zhejiang University, 
      Hangzhou, China.
FAU - Liu, Jiyang
AU  - Liu J
AD  - Department of Chemistry, Key Laboratory of Surface and Interface Science of 
      Polymer Materials of Zhejiang Province, Zhejiang Sci-Tech University, Hangzhou, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20220907
PL  - Switzerland
TA  - Front Chem
JT  - Frontiers in chemistry
JID - 101627988
PMC - PMC9490055
OTO - NOTNLM
OT  - 2,4,6trichlorophenol
OT  - electrochemical sensor
OT  - nanochannel array
OT  - prochloraz
OT  - three-dimensional graphene
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/09/27 06:00
MHDA- 2022/09/27 06:01
PMCR- 2022/01/01
CRDT- 2022/09/26 17:01
PHST- 2022/05/27 00:00 [received]
PHST- 2022/08/15 00:00 [accepted]
PHST- 2022/09/26 17:01 [entrez]
PHST- 2022/09/27 06:00 [pubmed]
PHST- 2022/09/27 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 954802 [pii]
AID - 10.3389/fchem.2022.954802 [doi]
PST - epublish
SO  - Front Chem. 2022 Sep 7;10:954802. doi: 10.3389/fchem.2022.954802. eCollection 
      2022.