PMID- 36157721
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220928
IS  - 2470-1343 (Electronic)
IS  - 2470-1343 (Linking)
VI  - 7
IP  - 37
DP  - 2022 Sep 20
TI  - Synthesis and Characterization of 1H-Imidazole-4,5-dicarboxylic 
      Acid-Functionalized Silver Nanoparticles: Dual Colorimetric Sensors of Zn(2+) and 
      Homocysteine.
PG  - 33423-33431
LID - 10.1021/acsomega.2c04165 [doi]
AB  - A colorimetric assay has been developed for Zn(2+) and homocysteine (Hcy) 
      detection using functionalized silver nanoparticles (AgNPs). AgNPs have been 
      synthesized using silver nitrate, where sodium citrate is used as a stabilizing 
      agent and NaBH(4) as a reducing agent. Then, the nanoparticles (citrate@AgNPs) 
      were functionalized with 1H-imidazole-4,5-dicarboxylic acid (IDCA). UV-visible 
      and FTIR spectra suggested that IDCA was functionalized on the surface of 
      citrate@AgNPs through the N atom of the imidazole ring. The IDCA-functionalized 
      silver nanoparticles (IDCA@AgNPs) simultaneously detected Zn(2+) and Hcy from 
      aqueous solution and showed different responses to the two analytes (Zn(2+) and 
      Hcy) based on the aggregation-induced color change of IDCA@AgNPs. They showed the 
      color change from yellow to red, which was easily discriminated by visual 
      inspection as well as UV-visible spectroscopy. The surface plasmon resonance 
      absorbance values of Zn(2+) and Hcy are 485 and 512 nm, respectively, when Zn(2+) 
      and Hcy react with IDCA@AgNPs. IDCA@AgNPs showed linearity with Zn(2+) and Hcy 
      concentrations, with the detection limit of 2.38 muM and 0.54 nM, respectively 
      (S/N = 3). The IDCA@AgNPs showed excellent selectivity toward Zn(2+) and Hcy 
      compared to the different metal ions and amino acids, respectively. Optimal 
      detection was achieved toward Zn(2+) and Hcy in the pH range 3-10. In addition, 
      IDCA@AgNPs were used to detect Zn(2+) and Hcy from lake water, showing low 
      interference.
CI  - (c) 2022 The Authors. Published by American Chemical Society.
FAU - Mondal, Palash
AU  - Mondal P
AUID- ORCID: 0000-0003-0649-1034
AD  - School of Molecular Sciences, Arizona State University, Tempe, Arizona 
      85287-1604, United States.
FAU - Yarger, Jeffery L
AU  - Yarger JL
AUID- ORCID: 0000-0002-7385-5400
AD  - School of Molecular Sciences, Arizona State University, Tempe, Arizona 
      85287-1604, United States.
LA  - eng
PT  - Journal Article
DEP - 20220907
PL  - United States
TA  - ACS Omega
JT  - ACS omega
JID - 101691658
PMC - PMC9494438
COIS- The authors declare no competing financial interest.
EDAT- 2022/09/27 06:00
MHDA- 2022/09/27 06:01
PMCR- 2022/09/07
CRDT- 2022/09/26 17:12
PHST- 2022/07/02 00:00 [received]
PHST- 2022/08/26 00:00 [accepted]
PHST- 2022/09/26 17:12 [entrez]
PHST- 2022/09/27 06:00 [pubmed]
PHST- 2022/09/27 06:01 [medline]
PHST- 2022/09/07 00:00 [pmc-release]
AID - 10.1021/acsomega.2c04165 [doi]
PST - epublish
SO  - ACS Omega. 2022 Sep 7;7(37):33423-33431. doi: 10.1021/acsomega.2c04165. 
      eCollection 2022 Sep 20.