PMID- 36159538 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20220928 IS - 2307-8960 (Print) IS - 2307-8960 (Electronic) IS - 2307-8960 (Linking) VI - 10 IP - 23 DP - 2022 Aug 16 TI - Reflections on the prevalence of human leukocyte antigen-B27 and human leukocyte antigen-B51 co-occurrence in patients with spondylarthritis. PG - 8422-8424 LID - 10.12998/wjcc.v10.i23.8422 [doi] AB - We performed a literature mini-review of the clinical profile of patients with spondylarthritis who are also human leukocyte antigen (HLA)-B51-positive. It seems to us that patients with HLA-B27 and HLA-B51 are more common in men, Asians and between the third and ninth decades of life. They are more likely to develop peripheral joint conditions, with cutaneous manifestations (e.g., oral ulcers) and uveitis. Therefore, more robust epidemiological studies with more accurate methodology and multicenter locations are needed to better map the role of the interaction between HLA-B51 in patients with spondylarthritis. CI - (c)The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. FAU - Goncalves Junior, Jucier AU - Goncalves Junior J AD - Division of Rheumatology, Sao Paulo University, Sao Paulo 01246-903, Sao Paulo, Brazil. juciergjunior@hotmail.com. FAU - Sampaio-Barros, Percival Degrava AU - Sampaio-Barros PD AD - Division of Rheumatology, Sao Paulo University, Sao Paulo 01246-903, Sao Paulo, Brazil. FAU - Shinjo, Samuel Katsuyuki AU - Shinjo SK AD - Division of Rheumatology, Sao Paulo University, Sao Paulo 01246-903, Sao Paulo, Brazil. LA - eng PT - Journal Article PL - United States TA - World J Clin Cases JT - World journal of clinical cases JID - 101618806 PMC - PMC9403693 OTO - NOTNLM OT - Ankylosing spondylitis OT - HLA-B27 OT - HLA-B51 OT - Human leukocyte antigen OT - Spondylarthritis COIS- Conflict-of-interest statement: The authors declare that they have no conflicts of interest. EDAT- 2022/09/27 06:00 MHDA- 2022/09/27 06:01 PMCR- 2022/08/16 CRDT- 2022/09/26 17:36 PHST- 2022/03/14 00:00 [received] PHST- 2022/05/14 00:00 [revised] PHST- 2022/07/18 00:00 [accepted] PHST- 2022/09/26 17:36 [entrez] PHST- 2022/09/27 06:00 [pubmed] PHST- 2022/09/27 06:01 [medline] PHST- 2022/08/16 00:00 [pmc-release] AID - 10.12998/wjcc.v10.i23.8422 [doi] PST - ppublish SO - World J Clin Cases. 2022 Aug 16;10(23):8422-8424. doi: 10.12998/wjcc.v10.i23.8422.