PMID- 36159566
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20231023
IS  - 1741-427X (Print)
IS  - 1741-4288 (Electronic)
IS  - 1741-427X (Linking)
VI  - 2022
DP  - 2022
TI  - Surfactant without Endotracheal Tube Intubation (SurE) versus 
      Intubation-Surfactant-Extubation (InSurE) in Neonatal Respiratory Distress 
      Syndrome: A Systematic Review and Meta-Analysis.
PG  - 6225282
LID - 10.1155/2022/6225282 [doi]
LID - 6225282
AB  - Neonatal respiratory distress syndrome (NRDS) is generally treated with 
      surfactant by intubation-surfactant-extubation (InSurE) technique, an invasive 
      method of surfactant administration. Surfactant without endotracheal tube 
      intubation (SurE) is a noninvasive technique that avoids intubation and has been 
      found to have improved the delivery of exogenous surfactants, thereby decreasing 
      lung damage in neonates. This systematic review aimed to provide insights into 
      the efficacy of SurE over InSurE in neonates who received respiratory support and 
      to evaluate the progression and onset of concurrent diseases after treatment. The 
      CENTRAL, PubMed, and Embase databases were searched for data collection. In all, 
      21 research articles were eligible, comprising 19,976 study participants. The 
      data showed a significant reduction in the composite outcome of stage 2 
      necrotizing enterocolitis, bronchopulmonary dysplasia, and onset of 
      hemodynamically significant patent ductus arteriosus when treated with SurE. The 
      trend towards lower pneumothorax rates with SurE was also evident. These findings 
      were robust due to the sensitivity analyses performed. There were no differences 
      in the outcome of death or rates of other neonatal morbidities. Overall, SurE was 
      identified as a better substitute for InSurE to treat neonates with RDS.
CI  - Copyright (c) 2022 Lirong Wang et al.
FAU - Wang, Lirong
AU  - Wang L
AUID- ORCID: 0000-0002-2937-8811
AD  - Department of Neonatology, YongZhou Central Hospital, Yongzhou, Hunan 425100, 
      China.
FAU - Zhang, Min
AU  - Zhang M
AD  - Department of Neonatology, YongZhou Central Hospital, Yongzhou, Hunan 425100, 
      China.
FAU - Yi, Qingfeng
AU  - Yi Q
AD  - Department of Neonatology, YongZhou Central Hospital, Yongzhou, Hunan 425100, 
      China.
LA  - eng
PT  - Journal Article
PT  - Retracted Publication
DEP - 20220916
PL  - United States
TA  - Evid Based Complement Alternat Med
JT  - Evidence-based complementary and alternative medicine : eCAM
JID - 101215021
RIN - Evid Based Complement Alternat Med. 2023 Oct 11;2023:9793852. PMID: 37868198
PMC - PMC9507732
COIS- The authors declare that they have no conflicts of interest.
EDAT- 2022/09/27 06:00
MHDA- 2022/09/27 06:01
PMCR- 2022/09/16
CRDT- 2022/09/26 17:36
PHST- 2022/07/21 00:00 [received]
PHST- 2022/08/11 00:00 [revised]
PHST- 2022/09/01 00:00 [accepted]
PHST- 2022/09/26 17:36 [entrez]
PHST- 2022/09/27 06:00 [pubmed]
PHST- 2022/09/27 06:01 [medline]
PHST- 2022/09/16 00:00 [pmc-release]
AID - 10.1155/2022/6225282 [doi]
PST - epublish
SO  - Evid Based Complement Alternat Med. 2022 Sep 16;2022:6225282. doi: 
      10.1155/2022/6225282. eCollection 2022.