PMID- 36161065
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230912
IS  - 0976-5662 (Print)
IS  - 2213-3445 (Electronic)
IS  - 0976-5662 (Linking)
VI  - 34
DP  - 2022 Nov
TI  - Impact of gender on outcomes following single-level anterior lumbar interbody 
      fusion.
PG  - 102019
LID - 10.1016/j.jcot.2022.102019 [doi]
LID - 102019
AB  - BACKGROUND: There have been a multitude of studies attempting to identify the 
      relationship between gender and postoperative outcomes; however, few studies have 
      examined how this relationship may affect outcomes after anterior lumbar 
      interbody fusion (ALIF) surgery. We aim to better characterize the impact that 
      self-reported gender may have on patient reported outcome measures (PROMs) and 
      achievement rates of minimum clinically important difference (MCID) after ALIF. 
      METHODS: A retrospective database of a single spine surgeon was searched for 
      patients who had undergone single-level ALIF. Indications for surgery including 
      acute trauma, infection, or malignancy were excluded. The population was 
      separated into cohorts by self-reported gender, female or male. PROMs were 
      recorded and compared within groups to their preoperative baselines and between 
      groups. MCID achievement rate was compared between groups. RESULTS: 140 patients 
      were identified for this study, with 68 patients self-identifying as female 
      gender. The male gender cohort was found to have a significantly greater 
      prevalence of hypertension (p = 0.018). Both cohorts showed significant 
      improvement during at least one or more postoperative time points for each 
      evaluated outcome measure (p </= 0.048, all). No significant difference in mean 
      PROM scores was noted between cohorts at any time point for any measured outcome. 
      The female gender cohort had significantly greater MCID achievement rates for 
      visual acuity scale (VAS) back pain overall and at the 6-month time point 
      (p </= 0.043, both). The female gender cohort also had significantly greater 
      achievement of MCID at the 1-year time point for VAS leg pain (p = 0.017). 
      CONCLUSION: Both female and male gender cohorts demonstrated significant 
      improvement in all outcomes measured at one or more postoperative time points. 
      Postoperative outcomes did not differ by gender. MCID achievement was more common 
      in female patients. Female patients may experience more tangible clinical 
      improvement after ALIF compared to male patients.
CI  - (c) 2022 Delhi Orthopedic Association. All rights reserved.
FAU - Hartman, Timothy J
AU  - Hartman TJ
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - Nie, James W
AU  - Nie JW
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - MacGregor, Keith R
AU  - MacGregor KR
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - Oyetayo, Omolabake O
AU  - Oyetayo OO
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - Zheng, Eileen
AU  - Zheng E
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
FAU - Singh, Kern
AU  - Singh K
AD  - Department of Orthopaedic Surgery, Rush University Medical Center, 1611 W. 
      Harrison St. Suite #300, Chicago, IL, 60612, USA.
LA  - eng
PT  - Journal Article
DEP - 20220911
PL  - India
TA  - J Clin Orthop Trauma
JT  - Journal of clinical orthopaedics and trauma
JID - 101559469
PMC - PMC9490097
OTO - NOTNLM
OT  - ALIF
OT  - ALIF, anterior lumbar interbody fusion
OT  - Gender
OT  - MCID
OT  - MCID, minimum clinically important difference
OT  - Outcomes
COIS- None.
EDAT- 2022/09/27 06:00
MHDA- 2022/09/27 06:01
PMCR- 2023/09/11
CRDT- 2022/09/26 18:00
PHST- 2022/07/08 00:00 [received]
PHST- 2022/08/15 00:00 [revised]
PHST- 2022/09/07 00:00 [accepted]
PHST- 2022/09/26 18:00 [entrez]
PHST- 2022/09/27 06:00 [pubmed]
PHST- 2022/09/27 06:01 [medline]
PHST- 2023/09/11 00:00 [pmc-release]
AID - S0976-5662(22)00255-7 [pii]
AID - 102019 [pii]
AID - 10.1016/j.jcot.2022.102019 [doi]
PST - epublish
SO  - J Clin Orthop Trauma. 2022 Sep 11;34:102019. doi: 10.1016/j.jcot.2022.102019. 
      eCollection 2022 Nov.