PMID- 36164471
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20220928
IS  - 2666-5204 (Electronic)
IS  - 2666-5204 (Linking)
VI  - 11
DP  - 2022 Sep
TI  - Self-reported limitations in physical function are common 6 months after 
      out-of-hospital cardiac arrest.
PG  - 100275
LID - 10.1016/j.resplu.2022.100275 [doi]
LID - 100275
AB  - TITLE: Self-reported limitations in physical function are common 6 months after 
      out-of-hospital cardiac arrest. BACKGROUND: Out-of-hospital cardiac arrest (OHCA) 
      survivors generally report good health-related quality of life, but physical 
      aspects of health seem more affected than other domains. Limitations in physical 
      function after surviving OHCA have received little attention. AIMS: To describe 
      physical function 6 months after OHCA and compare it with a group of ST elevation 
      myocardial infarction (STEMI) controls, matched for country, age, sex and time of 
      the cardiac event. A second aim was to explore variables potentially associated 
      with self-reported limitations in physical function in OHCA survivors. METHODS: A 
      cross-sectional sub-study of the Targeted Temperature Management at 33  degrees C versus 
      36  degrees C (TTM) trial with a follow-up 6 months post-event. Physical function was the 
      main outcome assessed with the self-reported Physical Functioning-10 items scale 
      (PF-10). PF-10 is presented as T-scores (0-100), where 50 represents the norm 
      mean. Scores <47 at a group level, or <45 at an individual level indicate 
      limitations in physical function. RESULTS: 287 OHCA survivors and 119 STEMI 
      controls participated. Self-reported physical function by PF-10 was significantly 
      lower for OHCA survivors compared to STEMI controls (mean 46.0, SD 11.2 vs. 48.8, 
      SD 9.0, p = 0.025). 38% of OHCA survivors compared to 26% of STEMI controls 
      reported limitations in physical function at an individual level (p = 0.022). The 
      most predictive variables for self-reported limitations in physical function in 
      OHCA survivors were older age, female sex, cognitive impairment, and symptoms of 
      anxiety and depression after 6 months. CONCLUSION: Self-reported limitations in 
      physical function are more common in OHCA survivors compared to STEMI controls. 
      TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01946932.
CI  - (c) 2022 The Author(s).
FAU - Heimburg, Katarina
AU  - Heimburg K
AD  - Lund University, Skane University Hospital, Department of Clinical Sciences Lund, 
      Neurology, Lund, Sweden.
FAU - Cronberg, Tobias
AU  - Cronberg T
AD  - Lund University, Skane University Hospital, Department of Clinical Sciences Lund, 
      Neurology, Lund, Sweden.
FAU - Tornberg, Asa B
AU  - Tornberg AB
AD  - Lund University, Department of Health Sciences, Lund, Sweden.
FAU - Ullen, Susann
AU  - Ullen S
AD  - Skane University Hospital, Clinical Studies Sweden - Forum South, Lund, Sweden.
FAU - Friberg, Hans
AU  - Friberg H
AD  - Lund University, Skane University Hospital, Department of Clinical Sciences Lund, 
      Intensive and Perioperative Care, Malmo, Sweden.
FAU - Nielsen, Niklas
AU  - Nielsen N
AD  - Lund University, Helsingborg Hospital, Department of Clinical Sciences Lund 
      Anesthesiology and Intensive Care, Lund, Sweden.
FAU - Hassager, Christian
AU  - Hassager C
AD  - Department of Cardiology, Rigshospitalet, Copenhagen, Denmark.
FAU - Horn, Janneke
AU  - Horn J
AD  - Department of Intensive Care, Amsterdam UMC, Amsterdam, Netherlands.
FAU - Kjaergaard, Jesper
AU  - Kjaergaard J
AD  - Department of Cardiology, Heart Center, Rigshospitalet, Denmark.
FAU - Kuiper, Michael
AU  - Kuiper M
AD  - Department of Intensive Care, Medical Center Leeuwarden, Leeuwarden, the 
      Netherlands.
FAU - Rylander, Christian
AU  - Rylander C
AD  - Department of Anesthesiology and Intensive Care Medicine, Institute of Clinical 
      Sciences, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
FAU - Wise, Matt P
AU  - Wise MP
AD  - Cardiff University School of Medicine, Cardiff, United Kingdom.
FAU - Lilja, Gisela
AU  - Lilja G
AD  - Lund University, Skane University Hospital, Department of Clinical Sciences Lund, 
      Neurology, Lund, Sweden.
LA  - eng
SI  - ClinicalTrials.gov/NCT01946932
PT  - Journal Article
DEP - 20220719
PL  - Netherlands
TA  - Resusc Plus
JT  - Resuscitation plus
JID - 101774410
PMC - PMC9508620
OTO - NOTNLM
OT  - Cardiac Arrest
OT  - Myocardial Infarction
OT  - Patient Reported Outcome Measures
OT  - Physical Function
COIS- The authors declare that they have no known competing financial interests or 
      personal relationships that could have appeared to influence the work reported in 
      this paper.
EDAT- 2022/09/28 06:00
MHDA- 2022/09/28 06:01
PMCR- 2022/07/19
CRDT- 2022/09/27 02:00
PHST- 2022/05/13 00:00 [received]
PHST- 2022/07/01 00:00 [revised]
PHST- 2022/07/04 00:00 [accepted]
PHST- 2022/09/27 02:00 [entrez]
PHST- 2022/09/28 06:00 [pubmed]
PHST- 2022/09/28 06:01 [medline]
PHST- 2022/07/19 00:00 [pmc-release]
AID - S2666-5204(22)00075-3 [pii]
AID - 100275 [pii]
AID - 10.1016/j.resplu.2022.100275 [doi]
PST - epublish
SO  - Resusc Plus. 2022 Jul 19;11:100275. doi: 10.1016/j.resplu.2022.100275. 
      eCollection 2022 Sep.