PMID- 36169428
OWN - NLM
STAT- MEDLINE
DCOM- 20231216
LR  - 20231216
IS  - 1678-2925 (Electronic)
IS  - 0004-2749 (Linking)
VI  - 87
IP  - 2
DP  - 2022
TI  - Retinal thickness profiles in patients with Behcet uveitis during remission.
PG  - 0174
LID - 10.5935/0004-2749.2021-0174 [doi]
AB  - PURPOSE: The purpose of this study was to evaluate the intraretinal layer 
      thickness in the macular region and its correlation with the duration of uveitis 
      and visual acuity in patients with Behcet uveitis. METHODS: In this 
      cross-sectional study, we included 93 eyes of 57 patients with Behcet uveitis and 
      100 eyes of 50 healthy individuals admitted to a tertiary center from January to 
      September 2017. We performed macular measurements in all subjects via spectral 
      domain-optical coherence tomography (SD-OCT) and divided the retina into layers 
      using automated segmentation software on the SD-OCT device. We then compared 
      layer thicknesses between the patient and control groups and evaluated the 
      correlation between OCT parameters and the duration of uveitis and visual acuity 
      in the patient group. RESULTS: Our records show a mean age of 37.9 +/- 10.8 (18-64) 
      years and 37.7 +/- 12.2 (21-61) years in the patient and control groups (p=0.821), 
      respectively. Meanwhile, data reveal a mean duration of uveitis of 6.9 +/- 4.7 
      (1-20) years. We found a reduction in the total outer layer thickness in the 
      patient group (p<0.001). However, we did not find a statistically significant 
      difference in the inner retinal layers except in the inner nuclear layer. The 
      duration of uveitis negatively correlated with the outer retinal layer's 
      thickness (correlation coefficient = -0.250). On the other hand, visual acuity 
      positively correlated with the central macular, the total inner layer, and the 
      outer retinal layer thicknesses (correlation coefficients: 0.194, 0.154, and 
      0.364, respectively). However, the inner nuclear layer negatively correlated with 
      visual acuity. CONCLUSIONS: Using retinal segmentation via SD-OCT for follow-ups 
      can help estimate visual loss in patients with Behcet uveitis, which can cause 
      significant changes in intraretinal layers in the macular region.
FAU - Farisogullari, Idil
AU  - Farisogullari I
AD  - Ophthalmology Clinic, Akyurt State Hospital, Ankara, Turkey.
FAU - Eser-Ozturk, Hilal
AU  - Eser-Ozturk H
AUID- ORCID: 0000-0002-0050-7894
AD  - Department of Ophthalmology, Ondokuz Mayis University Samsun, Turkey.
LA  - eng
PT  - Journal Article
DEP - 20220923
PL  - Brazil
TA  - Arq Bras Oftalmol
JT  - Arquivos brasileiros de oftalmologia
JID - 0400645
SB  - IM
MH  - Humans
MH  - Adult
MH  - Middle Aged
MH  - Cross-Sectional Studies
MH  - Retina/diagnostic imaging
MH  - *Behcet Syndrome/complications/diagnostic imaging
MH  - *Uveitis/diagnostic imaging/etiology
MH  - Visual Acuity
MH  - Tomography, Optical Coherence/methods
EDAT- 2022/09/29 06:00
MHDA- 2023/12/17 09:44
CRDT- 2022/09/28 10:07
PHST- 2021/04/19 00:00 [received]
PHST- 2022/03/14 00:00 [accepted]
PHST- 2023/12/17 09:44 [medline]
PHST- 2022/09/29 06:00 [pubmed]
PHST- 2022/09/28 10:07 [entrez]
AID - S0004-27492022005010205 [pii]
AID - 10.5935/0004-2749.2021-0174 [doi]
PST - epublish
SO  - Arq Bras Oftalmol. 2022 Sep 23;87(2):0174. doi: 10.5935/0004-2749.2021-0174. 
      eCollection 2022.