PMID- 36170129 OWN - NLM STAT- MEDLINE DCOM- 20220930 LR - 20220930 IS - 1660-9379 (Print) IS - 1660-9379 (Linking) VI - 18 IP - 797 DP - 2022 Sep 28 TI - [Dyspepsia: a more complex approach]. PG - 1784-1787 LID - 10.53738/REVMED.2022.18.797.1784 [doi] AB - Dyspepsia is defined as epigastric pain that lasts at least one month and may be associated with a range of other upper gastrointestinal symptoms. Approximately 2/3 of outpatients with dyspepsia have a functional dyspepsia. The clinical assessment of dyspepsia is based on age of patients as well and the search for severity criteria. The endoscopy in cases of new-onset dyspepsia is recommended from an age of 55-60 and the presence of at least 1 severity criteria. A non-invasive test for Helicobacter pylori (HP) should be performed in all patients and followed by HP eradication when HP test is positive. The first-choice treatment of functional dyspepsia is a proton pump inhibitor (PPI) at maximal dose for 8 weeks. A therapeutic trial with a prokinetic or a central neuromodulator are alternatives to consider in case of failure of PPI treatment. FAU - Mbadu Mbuzi, Eminence AU - Mbadu Mbuzi E AD - Service de medecine de premier recours, Hopitaux universitaires de Geneve, 1211 Geneve 14. FAU - Weber, Irene Paola AU - Weber IP AD - Service de medecine de premier recours, Hopitaux universitaires de Geneve, 1211 Geneve 14. FAU - Humair, Jean-Paul AU - Humair JP AD - Service de medecine de premier recours, Hopitaux universitaires de Geneve, 1211 Geneve 14. FAU - Gillabert, Cedric AU - Gillabert C AD - Centre medical de Lancy, Route de Chancy 59C, 1213 Petit-Lancy. FAU - Bastid, Caroline AU - Bastid C AD - Service de gastroenterologie et hepatologie, Hopitaux universitaires de Geneve, 1211 Geneve 14. LA - fre PT - Journal Article TT - Dyspepsie: une approche plus complexe. PL - Switzerland TA - Rev Med Suisse JT - Revue medicale suisse JID - 101219148 RN - 0 (Proton Pump Inhibitors) SB - IM MH - *Dyspepsia/diagnosis/etiology/therapy MH - *Gastritis/diagnosis/drug therapy MH - *Helicobacter Infections/complications/diagnosis/drug therapy MH - *Helicobacter pylori MH - Humans MH - Proton Pump Inhibitors/therapeutic use COIS- Les auteurs n'ont declare aucun conflit d'interets en relation avec cet article. EDAT- 2022/09/29 06:00 MHDA- 2022/10/01 06:00 CRDT- 2022/09/28 12:43 PHST- 2022/09/28 12:43 [entrez] PHST- 2022/09/29 06:00 [pubmed] PHST- 2022/10/01 06:00 [medline] AID - RMS0797-003 [pii] AID - 10.53738/REVMED.2022.18.797.1784 [doi] PST - ppublish SO - Rev Med Suisse. 2022 Sep 28;18(797):1784-1787. doi: 10.53738/REVMED.2022.18.797.1784.