PMID- 36177380 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221001 IS - 2042-8812 (Print) IS - 2042-8812 (Electronic) IS - 2042-8812 (Linking) VI - 2022 IP - 9 DP - 2022 Sep TI - The role of biodegradable temporizing matrix in the management of a patient with major burns and anorexia nervosa. PG - rjac410 LID - 10.1093/jscr/rjac410 [doi] LID - rjac410 AB - Severe malnutrition secondary to anorexia nervosa results in deeper burns and significantly impacts wound healing, which represents a major challenge to burn management. The use of acellular dermal matrices, such as biodegradable temporizing matrix (BTM), is a valuable tool to overcome the surgical limitations. We describe a case of a 36-year-old female with a background of anorexia nervosa (body mass index of 12.3) presenting with a 30% total burns surface area (TBSA) burn. All of her burns were excised down to fascia due to the absence of subcutaneous fat. Her thin skin and depleted nutritional status significantly impacted reconstructive options. BTM was utilized to create a neodermis and provide adequate time to optimize the nutritional status before autologous skin resurfacing 3 weeks later, which yielded robust coverage with minimal donor site morbidity. Despite initial surgical and nutritional challenges, excellent outcomes were achieved in terms of wound healing, scar contractures and mobility. CI - Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. (c) The Author(s) 2022. FAU - Tan, Poh AU - Tan P AD - Department of Burns and Plastic Surgery, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK. FAU - Shah, Rushabh AU - Shah R AUID- ORCID: 0000-0003-4047-7033 AD - Department of Burns and Plastic Surgery, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK. FAU - Hassouna, Tarek AU - Hassouna T AD - Department of Burns and Plastic Surgery, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK. FAU - Murphy, Ralph AU - Murphy R AD - Department of Burns and Plastic Surgery, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK. FAU - McNally, Samantha AU - McNally S AD - Department of Burns and Plastic Surgery, Wythenshawe Hospital, Southmoor Road, Manchester M23 9LT, UK. LA - eng PT - Case Reports DEP - 20220927 PL - England TA - J Surg Case Rep JT - Journal of surgical case reports JID - 101560169 PMC - PMC9514796 OTO - NOTNLM OT - anorexia nervosa OT - biodegradable temporizing matrix OT - burns OT - malnutrition EDAT- 2022/10/01 06:00 MHDA- 2022/10/01 06:01 PMCR- 2022/09/27 CRDT- 2022/09/30 02:47 PHST- 2022/08/02 00:00 [received] PHST- 2022/08/23 00:00 [accepted] PHST- 2022/09/30 02:47 [entrez] PHST- 2022/10/01 06:00 [pubmed] PHST- 2022/10/01 06:01 [medline] PHST- 2022/09/27 00:00 [pmc-release] AID - rjac410 [pii] AID - 10.1093/jscr/rjac410 [doi] PST - epublish SO - J Surg Case Rep. 2022 Sep 27;2022(9):rjac410. doi: 10.1093/jscr/rjac410. eCollection 2022 Sep.