PMID- 36181031
OWN - NLM
STAT- MEDLINE
DCOM- 20221004
LR  - 20230103
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 101
IP  - 39
DP  - 2022 Sep 30
TI  - Evaluation of right ventricular function in patients with pulmonary arterial 
      hypertension by different right ventricular-pulmonary artery coupling methods.
PG  - e30873
LID - 10.1097/MD.0000000000030873 [doi]
LID - e30873
AB  - To compare the accuracy of end-systolic elasticity (Ees)/arterial elasticity (Ea) 
      ratio measured by single beat estimation, pressure-volume loop and cardiac 
      magnetic resonance (CMR) combined volume method in patients with pulmonary artery 
      hypertension, and to find a feasible and reliable method to quantitatively 
      evaluate the function of right ventricle in patients with pulmonary artery 
      hypertension. Forty-nine pulmonary artery hypertension patients enrolled between 
      May 2017 and May 2018 in our hospital were retrospectively analyzed. Firstly, 
      measure Ees/Ea ratio by single beat estimation, pressure-volume loop and CMR 
      combined volume method, then, compare Ees/Ea ratio with New York Heart 
      Association (NYHA) classification and NT-proBNP value respectively to evaluate 
      the accuracy of the 3 methods. Ees/Ea ratio measured by single beat estimation is 
      2.07 +/- 1.01, correlation analysis is not statistically significant when compare 
      with NYHA classification and NT-proBNP value (P > .05). Ees/Ea ratio measured by 
      pressure-volume loop is 2.64 +/- 1.48, correlation analysis is not statistically 
      significant when compare with NYHA classification and NT-proBNP value (P > .05). 
      Ees/Ea ratio measured by CMR combined volume method is 0.72 +/- 0.43, correlation 
      analysis is statistically significant when compare with NYHA classification and 
      NT-proBNP with negative correlation (P < .05). Ees/Ea ratio decrease according to 
      the increase of NT-proBNP value and the NYHA classification. There is linear 
      regression equation between Ees/Ea ratio measured by CMR combined volume method 
      and log (NT-proBNP) value: Y = -0.257X + 1.45, and the linear regression equation 
      is statistically significant (P = .001). Ees/Ea ratio measured by CMR combined 
      volume method is a feasible and reliable method to quantitatively evaluate the 
      function of right ventricule in patients with pulmonary artery hypertension, 
      which might be further verified in a larger patient population.
CI  - Copyright (c) 2022 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Dong, Yaling
AU  - Dong Y
AD  - Department of Cardiology, Wuhan Asia Heart Hospital, Wuhan, PR China.
FAU - Li, Yu
AU  - Li Y
AUID- ORCID: 0000-0001-8229-8477
FAU - Song, Laichun
AU  - Song L
AUID- ORCID: 0000-0001-6524-7475
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Familial Primary Pulmonary Hypertension/complications
MH  - Heart Ventricles/diagnostic imaging
MH  - Humans
MH  - *Hypertension, Pulmonary
MH  - *Pulmonary Arterial Hypertension
MH  - Pulmonary Artery/diagnostic imaging
MH  - Retrospective Studies
MH  - Stroke Volume
MH  - *Ventricular Dysfunction, Right/complications
MH  - Ventricular Function, Right
PMC - PMC9524992
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2022/10/02 06:00
MHDA- 2022/10/05 06:00
PMCR- 2022/09/30
CRDT- 2022/10/01 01:02
PHST- 2022/10/01 01:02 [entrez]
PHST- 2022/10/02 06:00 [pubmed]
PHST- 2022/10/05 06:00 [medline]
PHST- 2022/09/30 00:00 [pmc-release]
AID - 00005792-202209300-00029 [pii]
AID - 10.1097/MD.0000000000030873 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2022 Sep 30;101(39):e30873. doi: 
      10.1097/MD.0000000000030873.