PMID- 36185931
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221004
IS  - 2168-8184 (Print)
IS  - 2168-8184 (Electronic)
IS  - 2168-8184 (Linking)
VI  - 14
IP  - 8
DP  - 2022 Aug
TI  - Ketosis-Prone Type 2 Diabetes (Flatbush Diabetes) in Remission: A Report of Two 
      Cases.
PG  - e28514
LID - 10.7759/cureus.28514 [doi]
LID - e28514
AB  - Diabetic ketoacidosis (DKA) is a triad of uncontrolled hyperglycemia, metabolic 
      acidosis, and increased total body ketone concentration. It is a well-known 
      manifestation of type 1 diabetes mellitus (T1DM). However, it can also be the 
      first presentation of type 2 diabetes mellitus (T2DM). This subtype of diabetes 
      shares the characteristics of both T1DM and T2DM and is called 'Flatbush 
      diabetes,' also known as 'ketosis-prone T2DM.' This article highlights the 
      importance of early identification of ketosis-prone T2DM (KPD). We describe two 
      cases of African American men with no past medical histories who presented with 
      unproved DKA as the first presentation of T2DM requiring initial intensive 
      insulin therapy, which was gradually withdrawn with the addition of metformin. 
      Both patients are currently insulin independent for more than 15 months. It is an 
      essential clinical entity to recognize as insulin independence positively impacts 
      the quality of life and decreases the economic burden on the health care system.
CI  - Copyright (c) 2022, Ji et al.
FAU - Ji, Beisi
AU  - Ji B
AD  - Internal Medicine, State University of New York Downstate Medical Center, New 
      York, USA.
FAU - Suresh, SumathaChannapatna
AU  - Suresh S
AD  - Internal Medicine, State University of New York Downstate Medical Center, New 
      York, USA.
FAU - Bally, Klynt
AU  - Bally K
AD  - Internal Medicine, State University of New York Downstate Medical Center, New 
      York, USA.
FAU - Naher, Kamrun
AU  - Naher K
AD  - Endocrinology, State University of New York Downstate Medical Center, New York, 
      USA.
FAU - Banerji, Mary A
AU  - Banerji MA
AD  - Endocrinology, State University of New York Downstate Medical Center, New York, 
      USA.
LA  - eng
PT  - Case Reports
DEP - 20220828
PL  - United States
TA  - Cureus
JT  - Cureus
JID - 101596737
PMC - PMC9514152
OTO - NOTNLM
OT  - flatbush diabetes
OT  - ketosis-prone type 2 diabetes
OT  - recovery of beta-cell function
OT  - remission
OT  - subgroup a-beta+
COIS- The authors have declared that no competing interests exist.
EDAT- 2022/10/04 06:00
MHDA- 2022/10/04 06:01
PMCR- 2022/08/28
CRDT- 2022/10/03 04:27
PHST- 2022/08/27 00:00 [accepted]
PHST- 2022/10/03 04:27 [entrez]
PHST- 2022/10/04 06:00 [pubmed]
PHST- 2022/10/04 06:01 [medline]
PHST- 2022/08/28 00:00 [pmc-release]
AID - 10.7759/cureus.28514 [doi]
PST - epublish
SO  - Cureus. 2022 Aug 28;14(8):e28514. doi: 10.7759/cureus.28514. eCollection 2022 
      Aug.