PMID- 36186780
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221004
IS  - 2296-858X (Print)
IS  - 2296-858X (Electronic)
IS  - 2296-858X (Linking)
VI  - 9
DP  - 2022
TI  - Is high intensity laser therapy more effective than other physical therapy 
      modalities for treating knee osteoarthritis? A systematic review and network 
      meta-analysis.
PG  - 956188
LID - 10.3389/fmed.2022.956188 [doi]
LID - 956188
AB  - BACKGROUND: The use of physical therapy modalities, especially high intensity 
      laser therapy (HILT), for individuals with knee osteoarthritis (KOA) is still 
      controversial. OBJECTIVE: To compare the effects of HILT to other physical 
      therapy modalities on symptoms and function in individuals with KOA. METHODS: Six 
      databases (PubMed, Embase, Cochrane Library, Web of Science, EBSCO, and PEDro) 
      were searched in March 2022. Included studies were randomized controlled trials 
      involving HILT conducted on individuals with KOA. The end-trial weighted mean 
      difference (WMD) and standard deviations (SD) with 95% confidence intervals (CI) 
      were analyzed. RESULTS: Ten studies with 580 participants were obtained, of which 
      nine were included in the final network meta-analysis. In terms of relieving 
      pain, HILT demonstrated the highest probability of being among the most effective 
      treatments, with surface under the cumulative ranking (SUCRA) = 100%, and 
      compared to a control (placebo laser or exercise or a combination of both) on the 
      visual analog scale (VAS) for pain it demonstrated significant benefits (WMD 
      1.66, 95% CI 1.48-1.84). For improving self-reported function, as measured by the 
      Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) total 
      scores, the HILT SUCRA value led with 98.9%. When individuals with KOA were 
      treated by HILT, the improvement in stiffness was statistically significant (WMD 
      0.78, 95% CI 0.52-1.04) but the amount of improvement was smaller than the 
      minimal clinically important difference (MCID). CONCLUSION: The current evidence 
      suggests that HILT may be more effective than other physical therapy modalities 
      for improving pain and function in individuals with KOA. For improving stiffness, 
      however, it may not be clinically effective. SYSTEMATIC REVIEW REGISTRATION: 
      [https://www.researchregistry.com], identifier [1148].
CI  - Copyright (c) 2022 Wu, Luan, Pranata, Witchalls, Adams, Bousie and Han.
FAU - Wu, Menglai
AU  - Wu M
AD  - School of Sports and Health, Shanghai University of International Business and 
      Economics, Shanghai, China.
FAU - Luan, Lijiang
AU  - Luan L
AD  - School of Exercise and Health, Shanghai University of Sport, Shanghai, China.
FAU - Pranata, Adrian
AU  - Pranata A
AD  - Department of Nursing and Allied Health, School of Health Sciences, Swinburne 
      University of Technology, Melbourne, VIC, Australia.
FAU - Witchalls, Jeremy
AU  - Witchalls J
AD  - Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, 
      Australia.
FAU - Adams, Roger
AU  - Adams R
AD  - Research Institute for Sport and Exercise, University of Canberra, Canberra, ACT, 
      Australia.
AD  - School of Physiotherapy, University of Sydney, Sydney, NSW, Australia.
FAU - Bousie, Jaquelin
AU  - Bousie J
AD  - Faculty of Health, University of Canberra, Canberra, ACT, Australia.
FAU - Han, Jia
AU  - Han J
AD  - College of Rehabilitation Sciences, Shanghai University of Medicine and Health 
      Sciences, Shanghai, China.
LA  - eng
PT  - Systematic Review
DEP - 20220915
PL  - Switzerland
TA  - Front Med (Lausanne)
JT  - Frontiers in medicine
JID - 101648047
PMC - PMC9520262
OTO - NOTNLM
OT  - high intensity laser therapy
OT  - knee osteoarthritis
OT  - network meta-analysis
OT  - physical therapy
OT  - systematic review
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/10/04 06:00
MHDA- 2022/10/04 06:01
PMCR- 2022/09/15
CRDT- 2022/10/03 04:40
PHST- 2022/05/30 00:00 [received]
PHST- 2022/08/19 00:00 [accepted]
PHST- 2022/10/03 04:40 [entrez]
PHST- 2022/10/04 06:00 [pubmed]
PHST- 2022/10/04 06:01 [medline]
PHST- 2022/09/15 00:00 [pmc-release]
AID - 10.3389/fmed.2022.956188 [doi]
PST - epublish
SO  - Front Med (Lausanne). 2022 Sep 15;9:956188. doi: 10.3389/fmed.2022.956188. 
      eCollection 2022.