PMID- 36189946
OWN - NLM
STAT- MEDLINE
DCOM- 20221107
LR  - 20230125
IS  - 1460-2202 (Electronic)
IS  - 0271-3683 (Linking)
VI  - 47
IP  - 12
DP  - 2022 Dec
TI  - Changes in the Hyperreflective Bands of Outer Retinal Layers after Idiopathic 
      Epiretinal Membrane Surgical Removal.
PG  - 1609-1614
LID - 10.1080/02713683.2022.2132513 [doi]
AB  - Purpose: The purpose of this study was to describe the relationship between the 
      outer retinal hyperreflective bands and visual acuity recovery after idiopathic 
      epiretinal macular membrane (ERM) surgical removal.Methods: A prospective 
      longitudinal non-comparative study was conducted that included a total of 68 
      patients with idiopathic ERM, who underwent consecutive 23 G pars plana 
      vitrectomy (PPV) at San Juan University Hospital (Alicante, Spain) from January 
      2019 to January 2021. All patients underwent a complete preoperative standard 
      ophthalmic examination, including measurement of best corrected visual acuity 
      (BCVA) and spectral-domain optical coherence tomography (SD-OCT) examination. 
      This protocol was repeated at 1 and 3 months after surgery.Results: Mean 
      preoperative decimal BCVA was 0.30 +/- 0.13 and disruption of the first, second, 
      third and fourth outer retinal hyperreflective bands was observed by SD-OCT in 9 
      (27.9%), 27 (39.7%), 33 (48.5%) and 17 patients (25%), respectively. BCVA 
      improved after ERM peeling at 1 and 3 months in all patients, regardless of the 
      presence of disruption in any hyperreflective band. Significantly larger 
      improvement of BCVA was found at 3 months after surgery in patients not showing 
      disruption of hyperreflective bands 1 and 4 (p = 0.048 and 0.001, 
      respectively).Conclusions: The integrity of the outer retinal hyperreflective 
      bands by SD-OCT in patients with idiopathic ERM is a valuable tool to determine 
      the visual prognosis of the surgical treatment of this condition. A successful 
      recovery of hyperreflective bands 1 and 4 with ERM surgery may be a potential 
      biomarker of the visual improvement achieved due to their important anatomical 
      relation with cone photoreceptors at the foveal level.
FAU - Molina Martin, Julio Cesar
AU  - Molina Martin JC
AD  - Department of Ophthalmology, University Hospital San Juan de Alicante, Sant Joan 
      d'Alacant, Spain.
FAU - Pinero, David P
AU  - Pinero DP
AD  - Department of Optics, Pharmacology and Anatomy, University of Alicante, San 
      Vicente del Raspeig, Spain.
FAU - Garcia Conca, Victor
AU  - Garcia Conca V
AD  - Department of Ophthalmology, University Hospital San Juan de Alicante, Sant Joan 
      d'Alacant, Spain.
FAU - Desco, M Carmen
AU  - Desco MC
AD  - FISABIO Oftalmologia Medica, Valencia, Spain.
FAU - Mataix-Boronat, Jorge
AU  - Mataix-Boronat J
AD  - FISABIO Oftalmologia Medica, Valencia, Spain.
FAU - Balboa Alonso, Maria
AU  - Balboa Alonso M
AD  - Department of Ophthalmology, University Hospital San Juan de Alicante, Sant Joan 
      d'Alacant, Spain.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20221011
PL  - England
TA  - Curr Eye Res
JT  - Current eye research
JID - 8104312
SB  - IM
MH  - Humans
MH  - *Epiretinal Membrane/diagnosis/surgery
MH  - Prospective Studies
MH  - Retrospective Studies
MH  - Vitrectomy/methods
MH  - Retina/diagnostic imaging
MH  - Tomography, Optical Coherence/methods
OTO - NOTNLM
OT  - Epiretinal membrane
OT  - external limiting membrane
OT  - optical coherence tomography
OT  - pars plana vitrectomy
OT  - photoreceptors
EDAT- 2022/10/04 06:00
MHDA- 2022/11/08 06:00
CRDT- 2022/10/03 07:03
PHST- 2022/10/04 06:00 [pubmed]
PHST- 2022/11/08 06:00 [medline]
PHST- 2022/10/03 07:03 [entrez]
AID - 10.1080/02713683.2022.2132513 [doi]
PST - ppublish
SO  - Curr Eye Res. 2022 Dec;47(12):1609-1614. doi: 10.1080/02713683.2022.2132513. Epub 
      2022 Oct 11.