PMID- 36193498
OWN - NLM
STAT- MEDLINE
DCOM- 20221005
LR  - 20230630
IS  - 1875-8630 (Electronic)
IS  - 0278-0240 (Print)
IS  - 0278-0240 (Linking)
VI  - 2022
DP  - 2022
TI  - Correlation between Glycated Haemoglobin Level, Cardiac Function, and Prognosis 
      in Patients with Diabetes Mellitus Combined with Myocardial Infarction.
PG  - 2191294
LID - 10.1155/2022/2191294 [doi]
LID - 2191294
AB  - OBJECTIVE: This study was to investigate the correlation between glycated 
      haemoglobin (HbA1c) level, cardiac function, and prognosis in patients with 
      diabetes mellitus combined with myocardial infarction. METHODS: Ninety-three 
      patients with type 2 diabetes mellitus combined with acute myocardial infarction 
      who were hospitalized and treated in our hospital from January 2021 to June 2021 
      were recruited for prospective analysis and equally divided into group A (HbA1c < 
      6.5%), group B (6.5% </= HbA1c </= 8.5%), and group C (HbA1c > 8.5%) using the random 
      number table method, with 31 patients in each group. General data of patients 
      were collected on admission and blood glucose and cardiac function indexes were 
      measured; the incidence of myocardial infarction and death during the follow-up 
      period was recorded at 6 months after discharge. RESULTS: There was a significant 
      difference in blood glucose (FBG) and HbA1c levels at fasting between the three 
      groups (P < 0.05). There were statistically significant differences in plasma 
      levels of N-terminal probrain natriuretic peptide (NT-proBNP) and uric acid (UA), 
      left ventricular end diastolic diameter (LVEDD), left ventricular end systolic 
      volume (LVESV), left ventricular ejection fraction (LVEF), and cardiac function 
      classification of the New York Heart Association (NYHA) among the three groups (P 
      < 0.05). By statistical analysis, the HbA1c level was positively correlated with 
      FBG, NT-proBNP, UA, LVEDD, LVESD, and NYHA grades but negatively correlated with 
      LVEF (P < 0.05). The incidence rate of myocardial infarction and mortality was 
      significantly higher in group C than in groups A and B (P < 0.05). CONCLUSION: 
      HbA1c level in patients with diabetes mellitus combined with myocardial 
      infarction is closely related to the degree of cardiac function damage. Glycated 
      haemoglobin levels are associated with the development of cardiac insufficiency 
      in patients with acute myocardial infarction; glycated haemoglobin is also an 
      independent predictor of major adverse cardiovascular events. Reasonable and 
      effective blood glucose control is of great significance to the prognosis of 
      patients.
CI  - Copyright (c) 2022 Guangwei Zeng et al.
FAU - Zeng, Guangwei
AU  - Zeng G
AD  - Department of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong 
      University, No.157 Xiwu Rd., Xi'an City, Shaanxi 710004, China.
AD  - Department of Cardiology, Section 2, Xi'an International Medical Center Hospital, 
      Xi'an City, Shaanxi 710100, China.
FAU - An, Huixian
AU  - An H
AD  - Department of Cardiology, Section 2, Xi'an International Medical Center Hospital, 
      Xi'an City, Shaanxi 710100, China.
FAU - Li, Wei
AU  - Li W
AD  - Department of Cardiology, Section 2, Xi'an International Medical Center Hospital, 
      Xi'an City, Shaanxi 710100, China.
FAU - Fang, Dong
AU  - Fang D
AD  - Department of Cardiology, Section 2, Xi'an International Medical Center Hospital, 
      Xi'an City, Shaanxi 710100, China.
FAU - Sun, Mengna
AU  - Sun M
AD  - Department of Cardiology, Section 2, Xi'an International Medical Center Hospital, 
      Xi'an City, Shaanxi 710100, China.
FAU - Zheng, Qiangsun
AU  - Zheng Q
AUID- ORCID: 0000-0001-8877-3566
AD  - Department of Cardiology, The Second Affiliated Hospital of Xi'an Jiaotong 
      University, No.157 Xiwu Rd., Xi'an City, Shaanxi 710004, China.
LA  - eng
PT  - Journal Article
PT  - Retracted Publication
DEP - 20220923
PL  - United States
TA  - Dis Markers
JT  - Disease markers
JID - 8604127
RN  - 0 (Blood Glucose)
RN  - 0 (Glycated Hemoglobin A)
RN  - 114471-18-0 (Natriuretic Peptide, Brain)
RN  - 268B43MJ25 (Uric Acid)
SB  - IM
RIN - Dis Markers. 2023 Jun 21;2023:9838245. PMID: 37387761
MH  - Blood Glucose
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Glycated Hemoglobin
MH  - Humans
MH  - *Myocardial Infarction
MH  - Natriuretic Peptide, Brain
MH  - Prognosis
MH  - Stroke Volume
MH  - Uric Acid
MH  - Ventricular Function, Left
PMC - PMC9525741
COIS- All authors declared that they have no financial conflict of interest.
EDAT- 2022/10/05 06:00
MHDA- 2022/10/06 06:00
PMCR- 2022/09/23
CRDT- 2022/10/04 02:04
PHST- 2022/08/11 00:00 [received]
PHST- 2022/08/23 00:00 [revised]
PHST- 2022/08/29 00:00 [accepted]
PHST- 2022/10/04 02:04 [entrez]
PHST- 2022/10/05 06:00 [pubmed]
PHST- 2022/10/06 06:00 [medline]
PHST- 2022/09/23 00:00 [pmc-release]
AID - 10.1155/2022/2191294 [doi]
PST - epublish
SO  - Dis Markers. 2022 Sep 23;2022:2191294. doi: 10.1155/2022/2191294. eCollection 
      2022.