PMID- 36194240
OWN - NLM
STAT- MEDLINE
DCOM- 20221031
LR  - 20221124
IS  - 1618-2650 (Electronic)
IS  - 1618-2642 (Linking)
VI  - 414
IP  - 28
DP  - 2022 Nov
TI  - Construction of ratiometric fluorescence sensor and test strip with smartphone 
      based on dual-emission carbon dots for the specific detection of 
      chlortetracycline.
PG  - 8143-8154
LID - 10.1007/s00216-022-04349-0 [doi]
AB  - Concerns about environmental and food contamination caused by chlortetracycline 
      (CTC) residues have prompted people to explore efficient and convenient CTC 
      monitoring platforms. However, the reported fluorescent probes generally fail to 
      selectively detect CTC due to the structural similarity of tetracycline 
      antibiotics. Herein, an intrinsic dual-emission carbon dots (D-CDs) ratiometric 
      fluorescence sensor was prepared for highly sensitive and selective determination 
      of CTC over other tetracyclines by one-step synthesis. The sensor exhibited a 
      significant fluorescence enhancement at 425 nm after introducing CTC. The 
      fluorescence "turn on" of the sensing system is due to aggregation-induced 
      emission (AIE) phenomenon formed by hydrogen bonds and pi conjugation promoting 
      the specific recognition of CTC by D-CDs. The linear detection varied from 0.98 
      to 143.67 ng mL(-1) with a low limit of detection (LOD) of 1.29 ng mL(-1) (R(2) = 
      0.998), which was lower than most reported in the literature. The D-CDs sensor 
      was applied to detect CTC in spiked milk, blocked normal human serum, and fish 
      samples with recoveries of 95.5-104.2% and relative standard deviations (RSDs) of 
      2.6%. Particularly, D-CDs based test papers with a smartphone were prepared for 
      portable and visual detection of CTC by analyzing the various color changes of 
      RGB of fluorescence color, with an LOD of 7.18 ng mL(-1) (R(2) = 0.9909). The 
      fluorescence sensor designed in this work could be used as a rapid tool with high 
      performance and selectivity for monitoring control in foods.
CI  - (c) 2022. Springer-Verlag GmbH Germany, part of Springer Nature.
FAU - Wang, Chunyan
AU  - Wang C
AD  - College of Food Science and Engineering, Northwest A&F University, Yangling, 
      Shaanxi, 712100, People's Republic of China.
FAU - Huang, Gengli
AU  - Huang G
AD  - College of Food Science and Engineering, Northwest A&F University, Yangling, 
      Shaanxi, 712100, People's Republic of China.
FAU - Luo, Xueli
AU  - Luo X
AD  - College of Food Science and Engineering, Northwest A&F University, Yangling, 
      Shaanxi, 712100, People's Republic of China.
FAU - Tang, Wenzhi
AU  - Tang W
AD  - College of Food Science and Engineering, Northwest A&F University, Yangling, 
      Shaanxi, 712100, People's Republic of China.
FAU - Yue, Tianli
AU  - Yue T
AD  - College of Food Science and Engineering, Northwest A&F University, Yangling, 
      Shaanxi, 712100, People's Republic of China.
FAU - Li, Zhonghong
AU  - Li Z
AD  - College of Food Science and Engineering, Northwest A&F University, Yangling, 
      Shaanxi, 712100, People's Republic of China. steveli@nwsuaf.edu.cn.
AD  - Laboratory of Quality & Safety Risk Assessment for Agro-products (Yangling) 
      Ministry of Agriculture, Yangling, 712100, Shaanxi, China. steveli@nwsuaf.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20221004
PL  - Germany
TA  - Anal Bioanal Chem
JT  - Analytical and bioanalytical chemistry
JID - 101134327
RN  - WCK1KIQ23Q (Chlortetracycline)
RN  - 7440-44-0 (Carbon)
RN  - 0 (Fluorescent Dyes)
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Animals
MH  - Humans
MH  - *Chlortetracycline
MH  - Carbon/chemistry
MH  - *Quantum Dots/chemistry
MH  - Smartphone
MH  - Limit of Detection
MH  - Fluorescent Dyes/chemistry
MH  - Spectrometry, Fluorescence
MH  - Anti-Bacterial Agents/chemistry
OTO - NOTNLM
OT  - Antibiotics
OT  - Carbon nanomaterial
OT  - Chlortetracycline
OT  - Food safety
OT  - Ratiometric fluorescent sensor
OT  - Visual detection
EDAT- 2022/10/05 06:00
MHDA- 2022/11/01 06:00
CRDT- 2022/10/04 11:12
PHST- 2022/07/31 00:00 [received]
PHST- 2022/09/20 00:00 [accepted]
PHST- 2022/09/06 00:00 [revised]
PHST- 2022/10/05 06:00 [pubmed]
PHST- 2022/11/01 06:00 [medline]
PHST- 2022/10/04 11:12 [entrez]
AID - 10.1007/s00216-022-04349-0 [pii]
AID - 10.1007/s00216-022-04349-0 [doi]
PST - ppublish
SO  - Anal Bioanal Chem. 2022 Nov;414(28):8143-8154. doi: 10.1007/s00216-022-04349-0. 
      Epub 2022 Oct 4.