PMID- 36195599
OWN - NLM
STAT- MEDLINE
DCOM- 20221006
LR  - 20221018
IS  - 2052-4463 (Electronic)
IS  - 2052-4463 (Linking)
VI  - 9
IP  - 1
DP  - 2022 Oct 4
TI  - A whole-body FDG-PET/CT Dataset with manually annotated Tumor Lesions.
PG  - 601
LID - 10.1038/s41597-022-01718-3 [doi]
LID - 601
AB  - We describe a publicly available dataset of annotated Positron Emission 
      Tomography/Computed Tomography (PET/CT) studies. 1014 whole body 
      Fluorodeoxyglucose (FDG)-PET/CT datasets (501 studies of patients with malignant 
      lymphoma, melanoma and non small cell lung cancer (NSCLC) and 513 studies without 
      PET-positive malignant lesions (negative controls)) acquired between 2014 and 
      2018 were included. All examinations were acquired on a single, state-of-the-art 
      PET/CT scanner. The imaging protocol consisted of a whole-body FDG-PET 
      acquisition and a corresponding diagnostic CT scan. All FDG-avid lesions 
      identified as malignant based on the clinical PET/CT report were manually 
      segmented on PET images in a slice-per-slice (3D) manner. We provide the 
      anonymized original DICOM files of all studies as well as the corresponding DICOM 
      segmentation masks. In addition, we provide scripts for image processing and 
      conversion to different file formats (NIfTI, mha, hdf5). Primary diagnosis, age 
      and sex are provided as non-imaging information. We demonstrate how this dataset 
      can be used for deep learning-based automated analysis of PET/CT data and provide 
      the trained deep learning model.
CI  - (c) 2022. The Author(s).
FAU - Gatidis, Sergios
AU  - Gatidis S
AUID- ORCID: 0000-0002-6928-4967
AD  - Max-Planck-Institute for Intelligent Systems, Empirical Inference Department, 
      Tuebingen, 72076, Germany. sergios.gatidis@tuebingen.mpg.de.
AD  - University Hospital Tubingen, Department of Radiology, Tubingen, 72076, Germany. 
      sergios.gatidis@tuebingen.mpg.de.
FAU - Hepp, Tobias
AU  - Hepp T
AD  - Max-Planck-Institute for Intelligent Systems, Empirical Inference Department, 
      Tuebingen, 72076, Germany.
AD  - University Hospital Tubingen, Department of Radiology, Tubingen, 72076, Germany.
FAU - Fruh, Marcel
AU  - Fruh M
AD  - University Hospital Tubingen, Department of Radiology, Tubingen, 72076, Germany.
FAU - La Fougere, Christian
AU  - La Fougere C
AD  - University Hospital Tubingen, Department of Nuclear Medicine and Clinical 
      Molecular Imaging, Tubingen, 72076, Germany.
AD  - Cluster of Excellence iFIT (EXC 2180) "Image-Guided and Functionally Instructed 
      Tumor Therapies", Tubingen, 72076, Germany.
AD  - German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ) Partner 
      Site Tubingen, Tubingen, 72076, Germany.
FAU - Nikolaou, Konstantin
AU  - Nikolaou K
AD  - University Hospital Tubingen, Department of Radiology, Tubingen, 72076, Germany.
AD  - Cluster of Excellence iFIT (EXC 2180) "Image-Guided and Functionally Instructed 
      Tumor Therapies", Tubingen, 72076, Germany.
FAU - Pfannenberg, Christina
AU  - Pfannenberg C
AD  - University Hospital Tubingen, Department of Radiology, Tubingen, 72076, Germany.
FAU - Scholkopf, Bernhard
AU  - Scholkopf B
AD  - Max-Planck-Institute for Intelligent Systems, Empirical Inference Department, 
      Tuebingen, 72076, Germany.
FAU - Kustner, Thomas
AU  - Kustner T
AUID- ORCID: 0000-0002-0353-4898
AD  - University Hospital Tubingen, Department of Radiology, Tubingen, 72076, Germany.
FAU - Cyran, Clemens
AU  - Cyran C
AD  - Hospital of the Ludwig-Maximilians-University, Department of Radiology, Munich, 
      81377, Germany.
FAU - Rubin, Daniel
AU  - Rubin D
AD  - Stanford University, School of Medicine, Department of Biomedical Data Science, 
      Stanford, 94305, USA.
LA  - eng
PT  - Dataset
PT  - Journal Article
DEP - 20221004
PL  - England
TA  - Sci Data
JT  - Scientific data
JID - 101640192
RN  - 0 (Radiopharmaceuticals)
RN  - 0Z5B2CJX4D (Fluorodeoxyglucose F18)
SB  - IM
MH  - *Carcinoma, Non-Small-Cell Lung
MH  - Fluorodeoxyglucose F18
MH  - Humans
MH  - *Lung Neoplasms/diagnostic imaging
MH  - Positron Emission Tomography Computed Tomography/methods
MH  - Radiopharmaceuticals
MH  - Tomography, X-Ray Computed/methods
PMC - PMC9532417
COIS- The authors declare no competing interests.
EDAT- 2022/10/05 06:00
MHDA- 2022/10/07 06:00
PMCR- 2022/10/04
CRDT- 2022/10/04 23:15
PHST- 2022/06/28 00:00 [received]
PHST- 2022/09/23 00:00 [accepted]
PHST- 2022/10/04 23:15 [entrez]
PHST- 2022/10/05 06:00 [pubmed]
PHST- 2022/10/07 06:00 [medline]
PHST- 2022/10/04 00:00 [pmc-release]
AID - 10.1038/s41597-022-01718-3 [pii]
AID - 1718 [pii]
AID - 10.1038/s41597-022-01718-3 [doi]
PST - epublish
SO  - Sci Data. 2022 Oct 4;9(1):601. doi: 10.1038/s41597-022-01718-3.