PMID- 36196407
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221007
IS  - 1507-1367 (Print)
IS  - 2083-4640 (Electronic)
IS  - 1507-1367 (Linking)
VI  - 27
IP  - 4
DP  - 2022
TI  - Integrated scoring approach to assess radiotherapy plan quality for breast cancer 
      treatment.
PG  - 707-716
LID - 10.5603/RPOR.a2022.0083 [doi]
AB  - BACKGROUND: Proposal of an integrated scoring approach assessing the quality of 
      different treatment techniques in a radiotherapy planning comparison. This 
      scoring method incorporates all dosimetric indices of planning target volumes 
      (PTVs) as well as organs at risk (OARs) and provides a single quantitative 
      measure to select an ideal plan. MATERIALS AND METHODS: The radiotherapy planning 
      techniques compared were field-in-field (FinF), intensity modulated radiation 
      therapy (IMRT), volumetric modulated arc therapy (VMAT), hybrid IMRT (H-IMRT), 
      and hybrid VMAT (H-VMAT). These plans were generated for twenty-five locally 
      advanced left-sided breast cancer patients. The PTVs were prescribed a 
      hypofractionation dose of 40.5 Gy in 15 fractions. The integrated score for each 
      planning technique was calculated using the proposed formula. RESULTS: An 
      integrated score value that is close to zero indicates a superior plan. The 
      integrated score that incorporates all dosimetric indices (PTVs and OARs) were 
      1.37, 1.64, 1.72, 1.18, and 1.24 for FinF, IMRT, VMAT, H-IMRT, and H-VMAT plans, 
      respectively. CONCLUSION: The proposed integrated scoring approach is scientific 
      to select a better plan and flexible to incorporate the patient-specific clinical 
      demands. This simple tool is useful to quantify the treatment techniques and able 
      to differentiate the acceptable and unacceptable plans.
CI  - (c) 2022 Greater Poland Cancer Centre.
FAU - Balaji, Karunakaran
AU  - Balaji K
AD  - School of Advanced Sciences, Vellore Institute of Technology, Vellore, India.
AD  - Department of Radiation Oncology, Gleneagles Global Hospitals, Chennai, India.
FAU - Ramasubramanian, Velayudham
AU  - Ramasubramanian V
AD  - School of Advanced Sciences, Vellore Institute of Technology, Vellore, India.
LA  - eng
PT  - Journal Article
DEP - 20220919
PL  - Poland
TA  - Rep Pract Oncol Radiother
JT  - Reports of practical oncology and radiotherapy : journal of Greatpoland Cancer 
      Center in Poznan and Polish Society of Radiation Oncology
JID - 100885761
PMC - PMC9521686
OTO - NOTNLM
OT  - IMRT
OT  - VMAT
OT  - breast cancer
OT  - dosimetric index
OT  - integrated score
COIS- Conflict of interest The authors declare no conflicts of interest.
EDAT- 2022/10/06 06:00
MHDA- 2022/10/06 06:01
PMCR- 2022/09/19
CRDT- 2022/10/05 01:50
PHST- 2021/11/08 00:00 [received]
PHST- 2022/07/05 00:00 [accepted]
PHST- 2022/10/05 01:50 [entrez]
PHST- 2022/10/06 06:00 [pubmed]
PHST- 2022/10/06 06:01 [medline]
PHST- 2022/09/19 00:00 [pmc-release]
AID - rpor-27-4-707 [pii]
AID - 10.5603/RPOR.a2022.0083 [doi]
PST - epublish
SO  - Rep Pract Oncol Radiother. 2022 Sep 19;27(4):707-716. doi: 
      10.5603/RPOR.a2022.0083. eCollection 2022.