PMID- 36209652 OWN - NLM STAT- MEDLINE DCOM- 20221216 LR - 20221221 IS - 1873-5800 (Electronic) IS - 0968-0160 (Linking) VI - 39 DP - 2022 Dec TI - Painful total knee arthroplasty: Infrapatellar branch of the saphenous nerve selective denervation. A case series. PG - 197-202 LID - S0968-0160(22)00149-1 [pii] LID - 10.1016/j.knee.2022.09.010 [doi] AB - INTRODUCTION: Total knee arthroplasty (TKA) is a reliable and widespread solution for knee osteoarthritis treatment, but about 20% of the patients complains of persisting pain. Neuroma formation in the IPBSN (infrapatellar branch of the saphenous nerve) is an undervalued cause of persistent anterior pain after TKA. The aim of this study was to evaluate the effectiveness of the selective neuroma denervation on patients satisfaction and pain improvement. MATHERIAL AND METHODS: Between 2014 and 2020, we evaluated 13 patients suffering from persistent anterior knee pain and numbness after TKA who underwent a surgical neurectomy of the IPBSN. After clinical assessment and diagnosis confirmation, we carried out the surgery. Short Form 12 Health (SF12), Oxford Knee Score (OKS), and Numeric Rating Scale (NRS) have been collected before and after the procedure. After the surgical treatment, the symptom's resolution and patients' satisfaction were attested by the achievement of the Minimal ClinicallyImportantDifference(MCID) of the self-administered patient-reported outcome measures (PROMs). RESULTS: Our results showed a statistically significant improvement (p < 0.05) of patients pain perception (mean NRS improvement -4.2, SD 2.5) and overall satisfaction (with a mean increase in OKS of 14.5 points SD 9.4, and in SF12 of 6.5 points SD 4.0). CONCLUSIONS: Hence, our study suggests that selective neuroma denervation may be an effective solution to improve the quality of life of patients who develop this complication after TKA. CI - Copyright (c) 2022 The Author(s). Published by Elsevier B.V. All rights reserved. FAU - Giannetti, Alessio AU - Giannetti A AD - Department of Life, Health and Environmental Sciences, University of L'Aquila, l'Aquila, Italy. FAU - Valentino, Luigi AU - Valentino L AD - Department of Life, Health and Environmental Sciences, University of L'Aquila, l'Aquila, Italy. FAU - Giovanni Mazzoleni, Manuel AU - Giovanni Mazzoleni M AD - Department of Life, Health and Environmental Sciences, University of L'Aquila, l'Aquila, Italy. FAU - Tarantino, Alessio AU - Tarantino A AD - Department of Life, Health and Environmental Sciences, University of L'Aquila, l'Aquila, Italy. FAU - Calvisi, Vittorio AU - Calvisi V AD - Department of Life, Health and Environmental Sciences, University of L'Aquila, l'Aquila, Italy. LA - eng PT - Journal Article DEP - 20221007 PL - Netherlands TA - Knee JT - The Knee JID - 9430798 SB - IM MH - Humans MH - *Arthroplasty, Replacement, Knee/adverse effects MH - Quality of Life MH - Knee Joint/surgery/innervation MH - Knee/surgery MH - *Osteoarthritis, Knee/surgery/etiology MH - Pain/etiology MH - Denervation/methods MH - Treatment Outcome OTO - NOTNLM OT - Anterior knee pain OT - Denervation OT - Infrapatellar branch OT - Saphenous nerve OT - Total knee arthroplasty COIS- Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2022/10/10 06:00 MHDA- 2022/12/15 06:00 CRDT- 2022/10/09 18:18 PHST- 2021/12/10 00:00 [received] PHST- 2022/07/17 00:00 [revised] PHST- 2022/09/18 00:00 [accepted] PHST- 2022/10/10 06:00 [pubmed] PHST- 2022/12/15 06:00 [medline] PHST- 2022/10/09 18:18 [entrez] AID - S0968-0160(22)00149-1 [pii] AID - 10.1016/j.knee.2022.09.010 [doi] PST - ppublish SO - Knee. 2022 Dec;39:197-202. doi: 10.1016/j.knee.2022.09.010. Epub 2022 Oct 7.