PMID- 36211224 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230202 IS - 1885-1398 (Electronic) IS - 1699-258X (Print) IS - 1699-258X (Linking) VI - 19 IP - 2 DP - 2023 Feb TI - Systemic lupus erythematosus myocarditis after COVID-19 vaccination. PG - 114-116 LID - 10.1016/j.reuma.2022.06.003 [doi] AB - INTRODUCTION: Cases of acute myocarditis have been after administration of the BNT162b2 and Ad26.COV2.S vaccine. OBJECTIVE: Describe another possible mechanism of myocarditis after COVID-19 vaccination. CASE PRESENTATION: We describe the clinical case of a 72-year-old female with pleuritic chest pain one week after the third of the BNT162b2 mRNA vaccine. Serological tests for cardiotropic pathogens were negative, and autoimmunity screening was positive with anti-nuclear antibody (ANA) in 1:160 dilution, Anti-double-stranded DNA (anti-dsDNA), and anti-histone antibodies. (18)F-fluoro-deoxy-glucose (FDG) positron emission tomography/computed tomography (PET/CT) showed a focal myocardial and pericardial inflammatory process in the cardiac apex. RESULTS AND DISCUSSION: Systemic lupus erythematosus (SLE) diagnosis was made with myocardial affection. As far as we know, this is the first report of a case of lupus myocarditis after the COVID-19 vaccine. CONCLUSION: Given the pathogenic rationales, the association between SLE and myocarditis should be considered. CI - (c) 2022 Elsevier Espana, S.L.U. and Sociedad Espanola de Reumatologia y Colegio Mexicano de Reumatologia. All rights reserved. FAU - Sogbe, Miguel AU - Sogbe M AD - Internal Medicine Department, Clinica Universidad de Navarra, Pamplona, Spain. FAU - Blanco-Di Matteo, Andres AU - Blanco-Di Matteo A AD - Internal Medicine Department, Clinica Universidad de Navarra, Pamplona, Spain. FAU - Di Frisco, I Madeleine AU - Di Frisco IM AD - Pulmonary Medicine Department, Clinica Universidad de Navarra, Pamplona, Spain. FAU - Bastidas, Juan Fernando AU - Bastidas JF AD - Nuclear Medicine Department, Clinica Universidad de Navarra, Pamplona, Spain. FAU - Salterain, Nahikari AU - Salterain N AD - Department of Cardiology, Clinica Universidad de Navarra, Pamplona, Spain. FAU - Gavira, Juan Jose AU - Gavira JJ AD - Department of Cardiology, Clinica Universidad de Navarra, Pamplona, Spain. LA - eng PT - Case Reports DEP - 20220728 PL - Spain TA - Reumatol Clin JT - Reumatologia clinica JID - 101293923 PMC - PMC9525201 OTO - NOTNLM OT - BNT162B2 messenger RNA OT - COVID-19 vaccination OT - Myocarditis OT - Systemic lupus erythematosus EDAT- 2022/10/11 06:00 MHDA- 2022/10/11 06:01 PMCR- 2022/07/28 CRDT- 2022/10/10 03:50 PHST- 2022/04/11 00:00 [received] PHST- 2022/06/27 00:00 [accepted] PHST- 2022/10/11 06:00 [pubmed] PHST- 2022/10/11 06:01 [medline] PHST- 2022/10/10 03:50 [entrez] PHST- 2022/07/28 00:00 [pmc-release] AID - S1699-258X(22)00155-3 [pii] AID - 10.1016/j.reuma.2022.06.003 [doi] PST - ppublish SO - Reumatol Clin. 2023 Feb;19(2):114-116. doi: 10.1016/j.reuma.2022.06.003. Epub 2022 Jul 28.