PMID- 36214278
OWN - NLM
STAT- MEDLINE
DCOM- 20221215
LR  - 20230415
IS  - 1098-108X (Electronic)
IS  - 0276-3478 (Print)
IS  - 0276-3478 (Linking)
VI  - 55
IP  - 12
DP  - 2022 Dec
TI  - Reciprocal relationships between personality disorders and eating disorders in a 
      prospective 17-year follow-up study.
PG  - 1753-1764
LID - 10.1002/eat.23823 [doi]
AB  - OBJECTIVE: This study aimed to report the presence of categorical and dimensional 
      personality disorders (PD) in adults with longstanding eating disorders (ED) over 
      a period of 17 years and to investigate whether changes in PD predict changes in 
      ED symptoms or vice versa. METHODS: In total, 62 of the 80 living patients (78% 
      response rate) with anorexia nervosa (n = 23), bulimia nervosa (n = 25), or other 
      specified feeding or ED (n = 14) at baseline were evaluated during hospital 
      treatment and at 1-year, 2-year, 5-year, and 17-year follow-up. PD were assessed 
      using the Structured Clinical Interview for DSM-IV Axis II disorders, and the 
      eating disorder examination (EDE) interview was used to assess ED. Data were 
      analyzed using multilevel modeling. RESULTS: From baseline to the 17-year 
      follow-up, the number of patients with any PD decreased significantly from 74.2% 
      to 24.2%, and the total number of PD diagnoses declined from 80 to 22. Mean EDE 
      score was significantly reduced from 4.2 (SD: 1.1) to 2.0 (SD: 1.6). There was a 
      positive association between ED and PD where the initial level of either disorder 
      was followed by similar levels of the other disorder throughout the entire 
      follow-up period. High baseline levels of borderline PD predicted less decrease 
      in ED symptoms. No significant within-person effects were found. CONCLUSIONS: 
      Both ED and PD significantly declined over time. As the severity of either 
      disorder seems to be associated with the other, thorough assessment and treatment 
      that incorporates both the ED psychopathology and the personality disturbances 
      are advisable. PUBLIC SIGNIFICANCE STATEMENT: While personality disorders were 
      highly prevalent in the sample of patients with longstanding eating disorders, 
      both disorders were significantly reduced at the 17-year follow-up. The disorders 
      are related in the sense that an initial high level of either disorder is 
      associated with a high level of the other over time. A thorough assessment and 
      attention to both illnesses are advisable in therapy. CLINICAL TRIAL IDENTIFIER: 
      NCT03968705.
CI  - (c) 2022 The Authors. International Journal of Eating Disorders published by Wiley 
      Periodicals LLC.
FAU - Eielsen, Hanna Punsvik
AU  - Eielsen HP
AUID- ORCID: 0000-0001-5815-7818
AD  - Research Institute, Modum Bad Psychiatric Centre, Vikersund, Norway.
AD  - Department of Psychology, University of Oslo, Oslo, Norway.
FAU - Vrabel, KariAnne
AU  - Vrabel K
AD  - Research Institute, Modum Bad Psychiatric Centre, Vikersund, Norway.
AD  - Department of Psychology, University of Oslo, Oslo, Norway.
FAU - Hoffart, Asle
AU  - Hoffart A
AD  - Research Institute, Modum Bad Psychiatric Centre, Vikersund, Norway.
AD  - Department of Psychology, University of Oslo, Oslo, Norway.
FAU - Ro, Oyvind
AU  - Ro O
AD  - Division of Mental Health and Addiction, Regional Department for Eating 
      Disorders, Oslo University Hospital, Oslo, Norway.
AD  - Division of Mental Health and Addiction, Institute of Clinical Medicine, 
      University of Oslo, Oslo, Norway.
FAU - Rosenvinge, Jan H
AU  - Rosenvinge JH
AD  - Department of Psychology, Faculty of Health Sciences, UiT - The Arctic University 
      of Norway, Tromso, Norway.
LA  - eng
SI  - ClinicalTrials.gov/NCT03968705
PT  - Journal Article
DEP - 20221010
PL  - United States
TA  - Int J Eat Disord
JT  - The International journal of eating disorders
JID - 8111226
SB  - IM
MH  - Humans
MH  - Follow-Up Studies
MH  - Prospective Studies
MH  - *Personality Disorders/diagnosis
MH  - *Feeding and Eating Disorders/diagnosis
PMC - PMC10092669
OTO - NOTNLM
OT  - eating disorders
OT  - follow-up
OT  - multilevel modeling
OT  - outcome
OT  - personality disorders
COIS- The author declares that there is no conflict of interest that could be perceived 
      as prejudicing the impartiality of the research reported.
EDAT- 2022/10/11 06:00
MHDA- 2022/12/15 06:00
PMCR- 2023/04/12
CRDT- 2022/10/10 06:32
PHST- 2022/09/28 00:00 [revised]
PHST- 2022/05/12 00:00 [received]
PHST- 2022/09/28 00:00 [accepted]
PHST- 2022/10/11 06:00 [pubmed]
PHST- 2022/12/15 06:00 [medline]
PHST- 2022/10/10 06:32 [entrez]
PHST- 2023/04/12 00:00 [pmc-release]
AID - EAT23823 [pii]
AID - 10.1002/eat.23823 [doi]
PST - ppublish
SO  - Int J Eat Disord. 2022 Dec;55(12):1753-1764. doi: 10.1002/eat.23823. Epub 2022 
      Oct 10.