PMID- 36214593
OWN - NLM
STAT- MEDLINE
DCOM- 20230309
LR  - 20230309
IS  - 1943-7730 (Electronic)
IS  - 0007-5027 (Linking)
VI  - 54
IP  - 2
DP  - 2023 Mar 7
TI  - Clinical Application of Prostatic Exosomal Protein and Prostate-Specific Antigen 
      Levels in the Detection of Prostate-Related Diseases.
PG  - 212-214
LID - 10.1093/labmed/lmac103 [doi]
AB  - OBJECTIVE: Our aim was to study the use of prostatic exosomal protein (PSEP) and 
      prostate-specific antigen (PSA) in diagnosis of prostate-related diseases. 
      METHODS: A total of 54 cases of acute prostatitis (AP), 72 cases of chronic 
      prostatitis (CP), and 36 cases of prostate cancer (PCa) were enrolled. Levels of 
      PSEP and PSA were analyzed. RESULTS: The positive rate and level of PSEP in CP 
      was highest (both P < .05). The total PSA (tPSA) level in PCa was the highest 
      (P < .05), followed by AP and CP. The free PSA (fPSA) level was lowest in CP 
      (P < .05); fPSA/tPSA in AP was the highest (P < .05). The PSEP level in type II 
      CP was higher than in type IIIa and type IIIb (both P < .05), and it was higher 
      in type IIIa than in type IIIb (P < .05). The tPSA level in type IIIb was the 
      lowest in the 3 types (both P < .05). The fPSA/tPSA in type IIIb was the highest 
      in the 3 types (P < .05). CONCLUSION: The PSEP combined with PSA better 
      distinguishes prostate-related diseases.
CI  - Published by Oxford University Press on behalf of American Society for Clinical 
      Pathology 2022.
FAU - Ge, Qiuxia
AU  - Ge Q
AD  - Department of Laboratory Medicine, First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, China.
FAU - Lou, Jianfang
AU  - Lou J
AD  - Department of Laboratory Medicine, First Affiliated Hospital of Nanjing Medical 
      University, Nanjing, China.
LA  - eng
PT  - Journal Article
PL  - England
TA  - Lab Med
JT  - Laboratory medicine
JID - 0250641
RN  - EC 3.4.21.77 (Prostate-Specific Antigen)
SB  - IM
MH  - Male
MH  - Humans
MH  - Prostate
MH  - Prostate-Specific Antigen
MH  - *Prostatitis/diagnosis
MH  - *Prostatic Neoplasms/diagnosis
OTO - NOTNLM
OT  - combination
OT  - prostate cancer
OT  - prostate-specific antigen
OT  - prostatic small extracorporeal protein
OT  - prostatitis
OT  - types
EDAT- 2022/10/11 06:00
MHDA- 2023/03/10 06:00
CRDT- 2022/10/10 09:12
PHST- 2022/10/11 06:00 [pubmed]
PHST- 2023/03/10 06:00 [medline]
PHST- 2022/10/10 09:12 [entrez]
AID - 6754826 [pii]
AID - 10.1093/labmed/lmac103 [doi]
PST - ppublish
SO  - Lab Med. 2023 Mar 7;54(2):212-214. doi: 10.1093/labmed/lmac103.