PMID- 36217455 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221012 IS - 2405-8440 (Print) IS - 2405-8440 (Electronic) IS - 2405-8440 (Linking) VI - 8 IP - 10 DP - 2022 Oct TI - Human health risk assessment of pesticide residues in vegetable and fruit samples in Gujarat State, India. PG - e10876 LID - 10.1016/j.heliyon.2022.e10876 [doi] LID - e10876 AB - The present study was initiated with the purpose to evaluate possible health risks associated with pesticide residues through consumption of vegetables and fruits by general population of Gujarat, India. A total of 1075 samples comprising of twelve different varieties of commonly consumed food commodities were collected from twenty-five divergent locations in Gujarat. The collected samples were extracted using QuEChERS method and analyzed for the presence of organophosphorus (OPs), organochlorine (OCs) and synthetic pyrethroids (SPs) pesticides using UHPLC-HR/MS, GC-muECD and GC-MS/SIM. The results indicated that 2.3% of vegetable and fruit samples showed the presence of pesticide residues exceeding maximum residue limits (MRLs). The results suggested that, detected residue levels in samples were within safe limits and their consumption will not pose any significant health risk to human. The outcomes present significant information regarding the status of vegetable and fruit contamination and pointed out the prerequisite for further studies with reference to monitoring of pesticides and other toxic contaminants in different samples for assessing cumulative health risk. CI - (c) 2022 The Authors. FAU - P, Sivaperumal AU - P S AD - ICMR- National Institute of Occupational Health, Ahmedabad- 380016, India. FAU - Thasale, Rupal AU - Thasale R AD - ICMR- National Institute of Occupational Health, Ahmedabad- 380016, India. FAU - Kumar, Dhirendra AU - Kumar D AD - ICMR- National Institute of Occupational Health, Ahmedabad- 380016, India. AD - ICMR- National Animal Resource Facility for Biomedical Research, Hyderabad- 500007, India. FAU - Mehta, Tejal G AU - Mehta TG AD - ICMR- National Institute of Occupational Health, Ahmedabad- 380016, India. FAU - Limbachiya, Riddhi AU - Limbachiya R AD - ICMR- National Institute of Occupational Health, Ahmedabad- 380016, India. LA - eng PT - Journal Article DEP - 20221003 PL - England TA - Heliyon JT - Heliyon JID - 101672560 PMC - PMC9547241 OTO - NOTNLM OT - Dietary intake OT - Fruits and vegetables OT - Health risk OT - Human consumption OT - Pesticide residues COIS- The authors declare no conflict of interest. EDAT- 2022/10/12 06:00 MHDA- 2022/10/12 06:01 PMCR- 2022/10/03 CRDT- 2022/10/11 01:48 PHST- 2022/05/30 00:00 [received] PHST- 2022/07/11 00:00 [revised] PHST- 2022/09/28 00:00 [accepted] PHST- 2022/10/11 01:48 [entrez] PHST- 2022/10/12 06:00 [pubmed] PHST- 2022/10/12 06:01 [medline] PHST- 2022/10/03 00:00 [pmc-release] AID - S2405-8440(22)02164-8 [pii] AID - e10876 [pii] AID - 10.1016/j.heliyon.2022.e10876 [doi] PST - epublish SO - Heliyon. 2022 Oct 3;8(10):e10876. doi: 10.1016/j.heliyon.2022.e10876. eCollection 2022 Oct.