PMID- 36228860
OWN - NLM
STAT- MEDLINE
DCOM- 20221109
LR  - 20221109
IS  - 1873-6424 (Electronic)
IS  - 0269-7491 (Linking)
VI  - 315
DP  - 2022 Dec 15
TI  - Understanding the biological impact of organic pollutants absorbed by 
      nanoplastics.
PG  - 120407
LID - S0269-7491(22)01621-9 [pii]
LID - 10.1016/j.envpol.2022.120407 [doi]
AB  - Many organisms are consuming food contaminated with micro- and nanoparticles of 
      plastics, some of which absorb persistent organic pollutants (POPs) from the 
      environment and acting as carrier vectors for increasing the bioavailability in 
      living organisms. We recently reported that polymethylmethacrylate (PMMA) 
      nanoparticles at low concentrations are not toxic to animal models tested. In 
      this study, the toxicity of diphenylamine (DPA) incorporated PMMA nanoparticles 
      are assessed using barnacle larvae as a model organism. The absorption capacity 
      of DPA from water for commercially available virgin PMMA microparticles is 
      relatively low (0.14 wt%) during a 48 h period, which did not induce exposure 
      toxicity to barnacle nauplii. Thus, PMMA nanoparticles encapsulated with high 
      concentrations of DPA (DPA-enc-PMMA) were prepared through a reported 
      precipitation method to achieve 40% loading of DPA inside the particles. Toxicity 
      of DPA-enc-PMMA nanoparticles were tested using freshly spawned acorn barnacle 
      nauplii. The observed mortality of nauplii from DPA-enc-PMMA exposure was 
      compared to the values obtained from pure DPA exposure in water. The mortality 
      among the exposed acorn barnacle nauplii did not exceed 50% even at a high 
      concentration of DPA inside the PMMA nanoparticles. The results suggest that the 
      slow release of pollutants from polymer nanoparticles may not induce significant 
      toxicity to the organism living in a dynamic environment. The impact of long-term 
      exposure of DPA absorbed plastic nanoparticles need to be investigated in the 
      future.
CI  - Copyright (c) 2022 Elsevier Ltd. All rights reserved.
FAU - Yip, Yong Jie
AU  - Yip YJ
AD  - Department of Chemistry, National University of Singapore, 3 Science Drive 3, 
      117543, Singapore.
FAU - Mahadevan, Gomathi
AU  - Mahadevan G
AD  - Department of Chemistry, National University of Singapore, 3 Science Drive 3, 
      117543, Singapore.
FAU - Tay, Teresa Stephanie
AU  - Tay TS
AD  - St. John's Island National Marine Laboratory, Tropical Marine Science Institute, 
      National University of Singapore, 18 Kent Ridge Road, 119227, Singapore.
FAU - Neo, Mei Lin
AU  - Neo ML
AD  - St. John's Island National Marine Laboratory, Tropical Marine Science Institute, 
      National University of Singapore, 18 Kent Ridge Road, 119227, Singapore.
FAU - Lay-Ming Teo, Serena
AU  - Lay-Ming Teo S
AD  - St. John's Island National Marine Laboratory, Tropical Marine Science Institute, 
      National University of Singapore, 18 Kent Ridge Road, 119227, Singapore.
FAU - Valiyaveettil, Suresh
AU  - Valiyaveettil S
AD  - Department of Chemistry, National University of Singapore, 3 Science Drive 3, 
      117543, Singapore. Electronic address: chmsv@nus.edu.sg.
LA  - eng
PT  - Journal Article
DEP - 20221010
PL  - England
TA  - Environ Pollut
JT  - Environmental pollution (Barking, Essex : 1987)
JID - 8804476
RN  - 0 (Microplastics)
RN  - 0 (Environmental Pollutants)
RN  - 9011-14-7 (Polymethyl Methacrylate)
RN  - 0 (Plastics)
RN  - 059QF0KO0R (Water)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Animals
MH  - Microplastics
MH  - *Environmental Pollutants
MH  - Polymethyl Methacrylate/toxicity
MH  - Plastics/toxicity
MH  - *Thoracica
MH  - *Nanoparticles/toxicity
MH  - Water
MH  - *Water Pollutants, Chemical/toxicity
OTO - NOTNLM
OT  - Barnacle nauplii
OT  - Diphenylamine
OT  - Leachate
OT  - Nanoplastics
OT  - Polymethylmethacrylate nanoparticles
OT  - Toxicity
COIS- Declaration of competing interest The authors declare the following financial 
      interests/personal relationships which may be considered as potential competing 
      interests: Suresh Valiyaveettil reports financial support was provided by 
      National Research Foundation Singapore, Singapore.
EDAT- 2022/10/14 06:00
MHDA- 2022/11/10 06:00
CRDT- 2022/10/13 19:35
PHST- 2022/08/15 00:00 [received]
PHST- 2022/10/01 00:00 [revised]
PHST- 2022/10/06 00:00 [accepted]
PHST- 2022/10/14 06:00 [pubmed]
PHST- 2022/11/10 06:00 [medline]
PHST- 2022/10/13 19:35 [entrez]
AID - S0269-7491(22)01621-9 [pii]
AID - 10.1016/j.envpol.2022.120407 [doi]
PST - ppublish
SO  - Environ Pollut. 2022 Dec 15;315:120407. doi: 10.1016/j.envpol.2022.120407. Epub 
      2022 Oct 10.