PMID- 36233590
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230308
IS  - 2077-0383 (Print)
IS  - 2077-0383 (Electronic)
IS  - 2077-0383 (Linking)
VI  - 11
IP  - 19
DP  - 2022 Sep 27
TI  - The Effects of His Bundle Pacing Compared to Classic Resynchronization Therapy in 
      Patients with Pacing-Induced Cardiomyopathy.
LID - 10.3390/jcm11195723 [doi]
LID - 5723
AB  - Pacing-induced cardiomyopathy (PICM) is among the most common right ventricular 
      pacing complications. Upgrading to cardiac resynchronization therapy (CRT) is the 
      recommended treatment option. Conduction system pacing with His bundle pacing 
      (HBP) has the potential to restore synchronous ventricular activation and can be 
      an alternative to biventricular pacing (BVP). Patients with PICM scheduled for a 
      system upgrade to CRT were included in the prospective cohort study. Either HBP 
      or BVP was used for CRT. Electrocardiographic, clinical, and echocardiographic 
      measurements were recorded at baseline and six-month follow-up. HBP was 
      successful in 44 of 53 patients (83%). Thirty-nine patients with HBP and 22 with 
      BVP completed a 6-month follow-up. HBP led to a higher reduction in QRS duration 
      than BVP, 118.3 +/- 14.20 ms vs. 150.5 +/- 18.64 ms, p < 0.0001. The improvement in 
      New York Heart Association (NYHA) class by one or two was more common in patients 
      with HBP than those with BiV (p = 0.04). Left ventricular ejection fraction 
      (LVEF) improved in BVP patients from 32.9 +/- 7.93% to 43.9 +/- 8.07%, p < 0.0001, 
      and in HBP patients from 34.9 +/- 6.45% to 48.6 +/- 7.73%, p < 0.0001. The 
      improvement in LVEF was more considerable in HBP patients than in BVP patients, p 
      = 0.019. The improvement in clinical outcomes and left ventricle reverse 
      remodeling was more significant with HBP than BVP. HBP can be a valid alternative 
      to BVP for upgrade procedures in PICM patients.
FAU - Gardas, Rafal
AU  - Gardas R
AUID- ORCID: 0000-0003-0002-1955
AD  - Department of Electrocardiology, Leszek Giec Upper-Silesian Medical Centre, 
      Silesian Medical University, 40-055 Katowice, Poland.
AD  - Department of Electrocardiology and Heart Failure, Medical University of Silesia, 
      40-007 Katowice, Poland.
FAU - Golba, Krzysztof S
AU  - Golba KS
AUID- ORCID: 0000-0001-5722-7976
AD  - Department of Electrocardiology, Leszek Giec Upper-Silesian Medical Centre, 
      Silesian Medical University, 40-055 Katowice, Poland.
AD  - Department of Electrocardiology and Heart Failure, Medical University of Silesia, 
      40-007 Katowice, Poland.
FAU - Soral, Tomasz
AU  - Soral T
AD  - Department of Electrocardiology, Leszek Giec Upper-Silesian Medical Centre, 
      Silesian Medical University, 40-055 Katowice, Poland.
FAU - Biernat, Jolanta
AU  - Biernat J
AUID- ORCID: 0000-0002-4396-9001
AD  - Department of Electrocardiology, Leszek Giec Upper-Silesian Medical Centre, 
      Silesian Medical University, 40-055 Katowice, Poland.
FAU - Kulesza, Piotr
AU  - Kulesza P
AD  - Department of Electrocardiology, Leszek Giec Upper-Silesian Medical Centre, 
      Silesian Medical University, 40-055 Katowice, Poland.
FAU - Sajdok, Mateusz
AU  - Sajdok M
AD  - Department of Electrocardiology, Leszek Giec Upper-Silesian Medical Centre, 
      Silesian Medical University, 40-055 Katowice, Poland.
FAU - Zub, Kamil
AU  - Zub K
AD  - Department of Electrocardiology, Leszek Giec Upper-Silesian Medical Centre, 
      Silesian Medical University, 40-055 Katowice, Poland.
LA  - eng
GR  - KNW-1-122/K/9/0/Medical University of Silesia/
PT  - Journal Article
DEP - 20220927
PL  - Switzerland
TA  - J Clin Med
JT  - Journal of clinical medicine
JID - 101606588
PMC - PMC9573163
OTO - NOTNLM
OT  - His bundle pacing
OT  - cardiac resynchronization therapy
OT  - conduction system pacing
OT  - pacing-induced cardiomyopathy
COIS- The authors declare no conflict of interest.
EDAT- 2022/10/15 06:00
MHDA- 2022/10/15 06:01
PMCR- 2022/09/27
CRDT- 2022/10/14 02:16
PHST- 2022/08/14 00:00 [received]
PHST- 2022/09/19 00:00 [revised]
PHST- 2022/09/22 00:00 [accepted]
PHST- 2022/10/14 02:16 [entrez]
PHST- 2022/10/15 06:00 [pubmed]
PHST- 2022/10/15 06:01 [medline]
PHST- 2022/09/27 00:00 [pmc-release]
AID - jcm11195723 [pii]
AID - jcm-11-05723 [pii]
AID - 10.3390/jcm11195723 [doi]
PST - epublish
SO  - J Clin Med. 2022 Sep 27;11(19):5723. doi: 10.3390/jcm11195723.