PMID- 36234988
OWN - NLM
STAT- MEDLINE
DCOM- 20221017
LR  - 20221019
IS  - 1420-3049 (Electronic)
IS  - 1420-3049 (Linking)
VI  - 27
IP  - 19
DP  - 2022 Sep 30
TI  - A Cyclen-Functionalized Cobalt-Substituted Sandwich-Type Tungstoarsenate with 
      Versatility in Removal of Methylene Blue and Anti-ROS-Sensitive Tumor Cells.
LID - 10.3390/molecules27196451 [doi]
LID - 6451
AB  - Oxidative degradation by using reactive oxygen species (ROS) is an effective 
      method to treat pollutants. The synthesis of artificial oxidase for the 
      degradation of dyes is a hot spot in molecular science. In this study, a 
      nanoscale sandwich-type polyoxometalate (POM) on the basis of a tetra-nuclear 
      cobalt cluster and trivacant B-alpha-Keggin-type tungstoarsenate 
      [Co(C(8)H(20)N(4))](4)Co(4)(H(2)O)(2)[HAsW(9)O(34)](2)∙4H(2)O (abbreviated as 
      CAW, C(8)H(20)N(4) = cyclen) has been synthesized and structurally examined by 
      infrared (IR) spectrum, ultraviolet-visible (UV-Vis) spectrum, X-ray 
      photoelectron spectrum (XPS), single-crystal X-ray diffraction (SXRD), and bond 
      valence sum (Sigmas) calculation. According to the structural analysis, the principal 
      element of the CAW is derived from modifying sandwich-type polyanion 
      Co(4)(H(2)O)(2) [HAsW(9)O(34)](2)(8)(-) with four [Co(Cyclen)](2+), in which 
      1,4,7,10-tetraazacyclododecane (cyclen) is firstly applied to modify POM. It is 
      also demonstrated that CAW is capable of efficiently catalyzing the production of 
      ROS by the synergistic effects of POM fragments and Co-cyclen complexes. 
      Moreover, CAW can interfere with the morphology and proliferation of sensitive 
      cells by producing ROS and exhibits ability in specifically eliminating methylene 
      blue (MB) dyes from the solution system by both adsorption and catalytic 
      oxidation.
FAU - Hua, Jiai
AU  - Hua J
AD  - Chemistry and Chemical Engineering Department, Taiyuan Institute of Technology, 
      Taiyuan 030008, China.
AD  - Laboratory of Biochemistry and Pharmacy, Taiyuan Institute of Technology, Taiyuan 
      030008, China.
FAU - Wei, Xueman
AU  - Wei X
AD  - Department of Geriatrics, First Affiliated Hospital of Naval Medical University, 
      Shanghai 200081, China.
FAU - Li, Yifeng
AU  - Li Y
AD  - Chemistry and Chemical Engineering Department, Taiyuan Institute of Technology, 
      Taiyuan 030008, China.
FAU - Li, Lingzhi
AU  - Li L
AD  - Laboratory of Biochemistry and Pharmacy, Taiyuan Institute of Technology, Taiyuan 
      030008, China.
FAU - Zhang, Hui
AU  - Zhang H
AD  - Chemistry and Chemical Engineering Department, Taiyuan Institute of Technology, 
      Taiyuan 030008, China.
FAU - Wang, Feng
AU  - Wang F
AD  - Laboratory of Biochemistry and Pharmacy, Taiyuan Institute of Technology, Taiyuan 
      030008, China.
FAU - Zhang, Changli
AU  - Zhang C
AD  - School of Environmental Science, Nanjing Xiaozhuang University, Nanjing 211171, 
      China.
FAU - Ma, Xiang
AU  - Ma X
AUID- ORCID: 0000-0001-7679-5741
AD  - Chemistry and Chemical Engineering Department, Taiyuan Institute of Technology, 
      Taiyuan 030008, China.
AD  - State Key Laboratory of Coordination Chemistry, School of Chemistry and Chemical 
      Engineering, Nanjing University, Nanjing 210023, China.
LA  - eng
GR  - 201901D211453 and 20210302124333/Shanxi Province Science Foundation for Youths/
GR  - STIP 2020L0643 and 2020L0644/Scientific and Technologial Innovation Programs of 
      Higher Education Institutions in Shanxi/
GR  - SKLCC202204/Research Foundation of the Chinese State Key Laboratory of 
      Coordination Chemistry/
PT  - Journal Article
DEP - 20220930
PL  - Switzerland
TA  - Molecules
JT  - Molecules (Basel, Switzerland)
JID - 100964009
RN  - 0 (Anions)
RN  - 0 (Arsenates)
RN  - 0 (Coloring Agents)
RN  - 0 (Cyclams)
RN  - 0 (Environmental Pollutants)
RN  - 0 (Polyelectrolytes)
RN  - 0 (Reactive Oxygen Species)
RN  - 0 (Tungsten Compounds)
RN  - 0 (polyoxometalate)
RN  - 12267-69-5 (tungstoarsenate)
RN  - 3G0H8C9362 (Cobalt)
RN  - 964584YO2O (cyclen)
RN  - EC 1.- (Oxidoreductases)
RN  - T42P99266K (Methylene Blue)
SB  - IM
MH  - Anions
MH  - Arsenates
MH  - Cobalt/chemistry
MH  - Coloring Agents
MH  - *Cyclams
MH  - *Environmental Pollutants
MH  - Methylene Blue/chemistry/pharmacology
MH  - Oxidoreductases
MH  - Polyelectrolytes
MH  - Reactive Oxygen Species
MH  - Tungsten Compounds
PMC - PMC9573041
OTO - NOTNLM
OT  - artificial oxidase
OT  - methylene blue dyes
OT  - nanoscale catalyst
OT  - reactive oxygen species
OT  - sandwich-type arsenomolybdate
COIS- The authors declare no conflict of interest.
EDAT- 2022/10/15 06:00
MHDA- 2022/10/18 06:00
PMCR- 2022/09/30
CRDT- 2022/10/14 02:26
PHST- 2022/08/01 00:00 [received]
PHST- 2022/09/25 00:00 [revised]
PHST- 2022/09/27 00:00 [accepted]
PHST- 2022/10/14 02:26 [entrez]
PHST- 2022/10/15 06:00 [pubmed]
PHST- 2022/10/18 06:00 [medline]
PHST- 2022/09/30 00:00 [pmc-release]
AID - molecules27196451 [pii]
AID - molecules-27-06451 [pii]
AID - 10.3390/molecules27196451 [doi]
PST - epublish
SO  - Molecules. 2022 Sep 30;27(19):6451. doi: 10.3390/molecules27196451.