PMID- 36236196 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20221019 IS - 2073-4360 (Electronic) IS - 2073-4360 (Linking) VI - 14 IP - 19 DP - 2022 Oct 10 TI - Improving Deproteinization in Colombian Latex from Hevea brasiliensis: A Bibliometric Approximation. LID - 10.3390/polym14194248 [doi] LID - 4248 AB - Natural Rubber Field Latex (NRFL) allergens restrict its use in some markets due to health-threatening allergic reactions. These molecules are proteins that are related to asymptomatic sensitization and hypersensitivity mediated by immunoglobulin E (IgE). Although NRFL allergens have been investigated since the 1980s, there are still gaps in knowledge regarding the development of deproteinized natural rubber (DPNR). Therefore, in this study, the deproteinization of NRFL from the lower basin of the Cauca River, Antioquia-Colombia was evaluated using eight systems. The highest removal value was 84.4% and was obtained from the treatment containing SDS (Sodium dodecyl sulfate), Urea, and Ethanol. It was also possible to determine that at high concentrations of SDS, removal percentages higher than 70% are reached. On the other hand, all deproteinizing systems decreased NRFL Zeta potentials without self-coagulation, suggesting enhanced colloidal stability in DPNR latex. On the other hand, the bibliometric analysis presented technological advances in DPRN through different parameters and bibliometric networks. The analysis presented makes an important contribution from the bibliometric approach that could be positive for the development of research on DPNR. FAU - Hernandez-Tenorio, Fabian AU - Hernandez-Tenorio F AUID- ORCID: 0000-0001-7467-8752 AD - School of Applied Sciences and Engineering, Universidad EAFIT, Medellin 050022, Colombia. FAU - Arroyave-Miranda, Hector AU - Arroyave-Miranda H AUID- ORCID: 0000-0003-3040-9053 AD - School of Applied Sciences and Engineering, Universidad EAFIT, Medellin 050022, Colombia. FAU - Miranda, Alejandra M AU - Miranda AM AD - Biological Sciences and Bioprocesses Group, School of Applied Sciences and Engineering, Universidad de EAFIT, Medellin 050022, Colombia. FAU - Gonzalez, Sandra M AU - Gonzalez SM AD - School of Applied Sciences and Engineering, Universidad EAFIT, Medellin 050022, Colombia. FAU - Rodriguez, Carlos A AU - Rodriguez CA AD - Engineering, Energy, Exergy and Sustainability Group (IEXS), School of Applied Sciences and Engineering, Universidad EAFIT, Medellin 050022, Colombia. FAU - Saez, Alex A AU - Saez AA AUID- ORCID: 0000-0001-5314-0515 AD - Biological Sciences and Bioprocesses Group, School of Applied Sciences and Engineering, Universidad de EAFIT, Medellin 050022, Colombia. LA - eng GR - 826-2018, 80740-490-2019/Ministry of Science and Gobernacion de Antioquia Colombia/ PT - Journal Article DEP - 20221010 PL - Switzerland TA - Polymers (Basel) JT - Polymers JID - 101545357 PMC - PMC9573318 OTO - NOTNLM OT - bibliometric analysis OT - deproteinization OT - latex OT - natural rubber OT - protein COIS- The authors declare no conflict of interest. EDAT- 2022/10/15 06:00 MHDA- 2022/10/15 06:01 PMCR- 2022/10/10 CRDT- 2022/10/14 02:34 PHST- 2022/09/19 00:00 [received] PHST- 2022/10/05 00:00 [revised] PHST- 2022/10/06 00:00 [accepted] PHST- 2022/10/14 02:34 [entrez] PHST- 2022/10/15 06:00 [pubmed] PHST- 2022/10/15 06:01 [medline] PHST- 2022/10/10 00:00 [pmc-release] AID - polym14194248 [pii] AID - polymers-14-04248 [pii] AID - 10.3390/polym14194248 [doi] PST - epublish SO - Polymers (Basel). 2022 Oct 10;14(19):4248. doi: 10.3390/polym14194248.