PMID- 36241836
OWN - NLM
STAT- MEDLINE
DCOM- 20230222
LR  - 20230222
IS  - 1614-7499 (Electronic)
IS  - 0944-1344 (Linking)
VI  - 30
IP  - 8
DP  - 2023 Feb
TI  - Residue levels and dietary risk assessment of fluopimomide, pyraclostrobin and 
      its metabolite BF-500-3 in garlic ecosystems under field conditions.
PG  - 19803-19813
LID - 10.1007/s11356-022-23512-9 [doi]
AB  - To evaluate the residue levels of fluopimomide, pyraclostrobin and its metabolite 
      BF-500-3 in garlic ecosystems, supervised garlic field trials with a commercial 
      formulation (pyraclostrobin.fluopimomide 30% suspension concentrate (SC)) were 
      conducted in six regions of China according to the Good Agricultural Practices 
      (GAP). The residues of fluopimomide, pyraclostrobin and BF-500-3 in field samples 
      were determined using a QuEChERS method combined with high-performance liquid 
      chromatography tandem mass spectrometry (HPLC-MS/MS). The average recoveries of 
      all target compounds were 76-94% with relative standard deviations (RSDs) of 
      1.0-14.5% and limits of quantitation (LOQs) of 0.002 mg/kg. At the recommended 
      pre-harvest interval (PHI, 10 days), the residues of fluopimomide, pyraclostrobin 
      and BF-500-3 were below 0.16, 0.77 and 0.12 mg/kg in garlic chive; below 0.027, 
      0.22 and 0.002 mg/kg in garlic scape; and below 0.002, 0.002 and 0.002 mg/kg in 
      garlic, respectively. Dietary intake risks were calculated using risk quotients 
      (RQs) based on field residual data, toxicological data and dietary patterns. The 
      chronic dietary risk quotients (RQc) of pyraclostrobin and fluopimomide were 
      48.42% and 0.36%, respectively. The acute dietary risk quotients (RQa) of 
      pyraclostrobin in garlic were 0.06-0.15%. These results indicated a low dietary 
      risk for consumers. This study could provide scientific guidance for the 
      application of pyraclostrobin and fluopimomide in garlic.
CI  - (c) 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, 
      part of Springer Nature.
FAU - Yu, Xiaoxu
AU  - Yu X
AD  - Lab of Pesticide Residues and Environmental Toxicology, School of Chemistry and 
      Biological Engineering, University of Science and Technology Beijing, 30 Xueyuan 
      Road, Haidian District, Beijing, 100083, People's Republic of China.
FAU - Hu, Jiye
AU  - Hu J
AD  - Lab of Pesticide Residues and Environmental Toxicology, School of Chemistry and 
      Biological Engineering, University of Science and Technology Beijing, 30 Xueyuan 
      Road, Haidian District, Beijing, 100083, People's Republic of China. 
      jyhu@ustb.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20221015
PL  - Germany
TA  - Environ Sci Pollut Res Int
JT  - Environmental science and pollution research international
JID - 9441769
RN  - DJW8M9OX1H (pyrachlostrobin)
RN  - 0 (Fungicides, Industrial)
RN  - 0 (Pesticide Residues)
RN  - 0 (Antioxidants)
SB  - IM
MH  - *Fungicides, Industrial/analysis
MH  - *Garlic
MH  - Tandem Mass Spectrometry/methods
MH  - Ecosystem
MH  - *Pesticide Residues/analysis
MH  - Antioxidants/analysis
MH  - Risk Assessment
MH  - China
OTO - NOTNLM
OT  - BF-500-3
OT  - Dietary risk
OT  - Fluopimomide
OT  - Garlic
OT  - Pyraclostrobin
OT  - Residue
EDAT- 2022/10/15 06:00
MHDA- 2023/02/22 06:00
CRDT- 2022/10/14 23:29
PHST- 2022/08/07 00:00 [received]
PHST- 2022/10/04 00:00 [accepted]
PHST- 2022/10/15 06:00 [pubmed]
PHST- 2023/02/22 06:00 [medline]
PHST- 2022/10/14 23:29 [entrez]
AID - 10.1007/s11356-022-23512-9 [pii]
AID - 10.1007/s11356-022-23512-9 [doi]
PST - ppublish
SO  - Environ Sci Pollut Res Int. 2023 Feb;30(8):19803-19813. doi: 
      10.1007/s11356-022-23512-9. Epub 2022 Oct 15.