PMID- 36244071 OWN - NLM STAT- MEDLINE DCOM- 20221129 LR - 20221129 IS - 1873-7072 (Electronic) IS - 0308-8146 (Linking) VI - 404 IP - Pt A DP - 2023 Mar 15 TI - An ultrasensitive sensing platform based on fluorescence carbon dots for chlorogenic acid determination in food samples. PG - 134395 LID - S0308-8146(22)02357-3 [pii] LID - 10.1016/j.foodchem.2022.134395 [doi] AB - In this work, an ultrasensitive and convenient method was established for chlorogenic acid (CGA) determination based on fluorescence quenching of carbon dots (CDs). The CDs were prepared by hydrothermal heating of citric acid and p-phenylenediamine. The proposed CDs-based sensing platform showed high selectivity and sensitivity towards CGA detection. Under optimal working conditions, the fluorescence signals of CDs decreased with increasing of CGA contents and presented linear response to CGA content in two ranges of 0.01-0.1 and 0.1-20.0 muM. The detection limits were as low as 8.87 nM and 0.12 muM. The proposed method was successfully applied to analyze CGA in real food samples. The recoveries were between 98.9 % and 106.7 % and the relative standard deviations (RSDs) were below 3.28 %. This work highlights the construction of a facial, simple, economic and highly sensitive fluorescence sensing system for CGA detection with promising application prospects in food analysis. CI - Copyright (c) 2022 Elsevier Ltd. All rights reserved. FAU - Hu, Qin AU - Hu Q AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, Jiangsu 225001, PR China. Electronic address: qinhu@yzu.edu.cn. FAU - Wang, Wenhui AU - Wang W AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, Jiangsu 225001, PR China. FAU - Yang, Zhen-Quan AU - Yang ZQ AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, Jiangsu 225001, PR China. FAU - Xiao, Lixia AU - Xiao L AD - College of Food Science and Engineering, Yangzhou University, Yangzhou, Jiangsu 225001, PR China. FAU - Gong, Xiaojuan AU - Gong X AD - Institute of Environmental Science, and School of Chemistry and Chemical Engineering, Shanxi University, Taiyuan 030006, PR China. FAU - Liu, Lizhen AU - Liu L AD - School of Chemistry and Environmental Engineering, Shanxi Datong University, Datong 037009, PR China. FAU - Han, Jie AU - Han J AD - School of Chemistry and Chemical Engineering, Yangzhou University, Yangzhou, Jiangsu, PR China. Electronic address: hanjie@yzu.edu.cn. LA - eng PT - Journal Article DEP - 20220926 PL - England TA - Food Chem JT - Food chemistry JID - 7702639 RN - 7440-44-0 (Carbon) RN - 318ADP12RI (Chlorogenic Acid) RN - 0 (Fluorescent Dyes) SB - IM MH - *Carbon MH - *Quantum Dots MH - Chlorogenic Acid MH - Spectrometry, Fluorescence/methods MH - Fluorescent Dyes OTO - NOTNLM OT - CDs OT - CGA OT - Fluorescence quenching OT - Food samples COIS- Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2022/10/17 06:00 MHDA- 2022/11/30 06:00 CRDT- 2022/10/16 18:03 PHST- 2022/05/10 00:00 [received] PHST- 2022/09/20 00:00 [revised] PHST- 2022/09/21 00:00 [accepted] PHST- 2022/10/17 06:00 [pubmed] PHST- 2022/11/30 06:00 [medline] PHST- 2022/10/16 18:03 [entrez] AID - S0308-8146(22)02357-3 [pii] AID - 10.1016/j.foodchem.2022.134395 [doi] PST - ppublish SO - Food Chem. 2023 Mar 15;404(Pt A):134395. doi: 10.1016/j.foodchem.2022.134395. Epub 2022 Sep 26.