PMID- 36245528
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20221019
IS  - 2296-861X (Print)
IS  - 2296-861X (Electronic)
IS  - 2296-861X (Linking)
VI  - 9
DP  - 2022
TI  - Simultaneous determination of twelve mycotoxins in edible oil, soy sauce and bean 
      sauce by PRiME HLB solid phase extraction combined with HPLC-Orbitrap HRMS.
PG  - 1001671
LID - 10.3389/fnut.2022.1001671 [doi]
LID - 1001671
AB  - A solid phase extraction-high-performance liquid chromatography-tandem Orbitrap 
      high resolution mass spectrometry (HPLC-Orbitrap HRMS) method was established for 
      the determination of 12 mycotoxins (ochratoxin A, ochratoxin B, aflatoxin B1, 
      aflatoxin B2, aflatoxin G1, aflatoxin G2, HT-2 toxin, sterigmatocystin, 
      diacetoxysciroenol, penicillic acid, mycophenolic acid, and citreoviridin) in 
      edible oil, soy sauce, and bean sauce. Samples were extracted by 80:20 (v:v) 
      acetonitrile-water solution, purified by PRiME HLB column, separated by aQ C18 
      column with mobile phase consisting of 0.5 mmol/L ammonium acetate-0.1% formic 
      acid aqueous solution and methanol. The results showed that the limits of 
      detection (LODs) and limits of quantification (LOQs) of 12 mycotoxins were 
      0.12-1.2 mug/L and 0.40-4.0 mug/L, respectively. The determination coefficients of 
      12 mycotoxins in the range of 0.20-100 mug/L were > 0.998. The average recoveries 
      in soy sauce and bean sauce were 78.4-106.8%, and the relative standard 
      deviations (RSDs) were 1.2-9.7% under three levels, including LOQ, 2x LOQ and 10 
      x LOQ. The average recoveries in edible oil were 78.3-115.6%, and the precision 
      RSD (n = 6) was 0.9-8.6%. A total of 24 edible oils, soy sauce and bean sauce 
      samples were analyzed by this method. AFB1, AFB2, sterigmatocystin and 
      mycophenolic acid were detected in several samples at concentrations ranging from 
      1.0 to 22.1 mug/kg. The method is simple, sensitive, and rapid and can be used for 
      screening and quantitative analysis of mycotoxin contamination in edible oil, soy 
      sauce, and bean sauce.
CI  - Copyright (c) 2022 Luo, Guan, Dong, Chen, Liang, Zhou, Xian and Xu.
FAU - Luo, Donghui
AU  - Luo D
AD  - College of Food Science and Engineering, Guangdong Ocean University, Yangjiang, 
      China.
AD  - Chaozhou Branch of Chemistry and Chemical Engineering Guangdong Laboratory 
      (Hanjiang Laboratory), Chaozhou, China.
FAU - Guan, Jingjing
AU  - Guan J
AD  - College of Food Science and Engineering, Guangdong Ocean University, Yangjiang, 
      China.
FAU - Dong, Hao
AU  - Dong H
AD  - Key Laboratory of Green Processing and Intelligent Manufacturing of Lingnan 
      Specialty Food, Guangdong Provincial Key Laboratory of Lingnan Specialty Food 
      Science and Technology, College of Light Industry and Food Sciences, Ministry of 
      Agriculture, Zhongkai University of Agriculture and Engineering, Guangzhou, 
      China.
FAU - Chen, Jin
AU  - Chen J
AD  - College of Food Science and Engineering, Guangdong Ocean University, Yangjiang, 
      China.
FAU - Liang, Ming
AU  - Liang M
AD  - Guangzhou Quality Supervision and Testing Institute, Guangzhou, China.
FAU - Zhou, Chunxia
AU  - Zhou C
AD  - College of Food Science and Engineering, Guangdong Ocean University, Yangjiang, 
      China.
FAU - Xian, Yanping
AU  - Xian Y
AD  - Guangzhou Quality Supervision and Testing Institute, Guangzhou, China.
FAU - Xu, Xiaofei
AU  - Xu X
AD  - College of Food Science and Engineering, Guangdong Ocean University, Yangjiang, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20220928
PL  - Switzerland
TA  - Front Nutr
JT  - Frontiers in nutrition
JID - 101642264
PMC - PMC9555343
OTO - NOTNLM
OT  - HPLC-Orbitrap HRMS
OT  - PRiME HLB
OT  - edible oil
OT  - mycotoxin
OT  - soy sauce
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2022/10/18 06:00
MHDA- 2022/10/18 06:01
PMCR- 2022/01/01
CRDT- 2022/10/17 04:15
PHST- 2022/07/23 00:00 [received]
PHST- 2022/09/09 00:00 [accepted]
PHST- 2022/10/17 04:15 [entrez]
PHST- 2022/10/18 06:00 [pubmed]
PHST- 2022/10/18 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fnut.2022.1001671 [doi]
PST - epublish
SO  - Front Nutr. 2022 Sep 28;9:1001671. doi: 10.3389/fnut.2022.1001671. eCollection 
      2022.