PMID- 36249419 OWN - NLM STAT- MEDLINE DCOM- 20221018 LR - 20221019 IS - 2314-7156 (Electronic) IS - 2314-8861 (Print) IS - 2314-7156 (Linking) VI - 2022 DP - 2022 TI - Recent Advances in the Allergic Cross-Reactivity between Fungi and Foods. PG - 7583400 LID - 10.1155/2022/7583400 [doi] LID - 7583400 AB - Airborne fungi are one of the most ubiquitous kinds of inhalant allergens which can result in allergic diseases. Fungi tend to grow in warm and humid environments with regional and seasonal variations. Their nomenclature and taxonomy are related to the sensitization of immunoglobulin E (IgE). Allergic cross-reactivity among different fungal species appears to be widely existing. Fungus-related foods, such as edible mushrooms, mycoprotein, and fermented foods by fungi, can often induce to fungus food allergy syndrome (FFAS) by allergic cross-reactivity with airborne fungi. FFAS may involve one or more target organs, including the oral mucosa, the skin, the gastrointestinal and respiratory tracts, and the cardiovascular system, with various allergic symptoms ranging from oral allergy syndrome (OAS) to severe anaphylaxis. This article reviews the current knowledge on the field of allergic cross-reactivity between fungal allergens and related foods, as well as the diagnosis and treatment on FFAS. CI - Copyright (c) 2022 Haiyan Xing et al. FAU - Xing, Haiyan AU - Xing H AD - Department of Allergy, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, China. AD - Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China. FAU - Wang, Jianyong AU - Wang J AD - Department of Pediatric, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, China. FAU - Sun, Yuemei AU - Sun Y AD - Department of Allergy, The Affiliated Yantai Yuhuangding Hospital of Qingdao University, Yantai, Shandong 264000, China. FAU - Wang, Hongtian AU - Wang H AUID- ORCID: 0000-0001-7204-7527 AD - Department of Allergy, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China. LA - eng PT - Journal Article PT - Review DEP - 20221007 PL - Egypt TA - J Immunol Res JT - Journal of immunology research JID - 101627166 RN - 0 (Allergens) RN - 37341-29-0 (Immunoglobulin E) SB - IM MH - *Allergens MH - Cross Reactions MH - *Food Hypersensitivity/diagnosis MH - Fungi MH - Immunoglobulin E PMC - PMC9568318 COIS- The authors declare no conflict of interest in relation to this work. EDAT- 2022/10/18 06:00 MHDA- 2022/10/19 06:00 PMCR- 2022/10/07 CRDT- 2022/10/17 05:22 PHST- 2022/07/13 00:00 [received] PHST- 2022/08/29 00:00 [revised] PHST- 2022/09/19 00:00 [accepted] PHST- 2022/10/17 05:22 [entrez] PHST- 2022/10/18 06:00 [pubmed] PHST- 2022/10/19 06:00 [medline] PHST- 2022/10/07 00:00 [pmc-release] AID - 10.1155/2022/7583400 [doi] PST - epublish SO - J Immunol Res. 2022 Oct 7;2022:7583400. doi: 10.1155/2022/7583400. eCollection 2022.