PMID- 36251183 OWN - NLM STAT- MEDLINE DCOM- 20230222 LR - 20230222 IS - 1614-7499 (Electronic) IS - 0944-1344 (Linking) VI - 30 IP - 8 DP - 2023 Feb TI - Health risk assessment of PAHs in fruit juice samples marketed in city of Tehran, Iran. PG - 20077-20088 LID - 10.1007/s11356-022-22763-w [doi] AB - The objective of the present study was to investigate the level of 16 PAHs in fruit juice samples (orange, apple, peach, pineapple, and mango) with three different packages (PET bottle, Tetra Pak, and canned packaging) by using MSPE/GC-MS (magnetic solid-phase extraction and gas chromatography-mass spectrometry) method. In this method limit of detection (LOD), and limit of quantitation (LOQ), and recovery were 0.030-0.280 mug/L, 0.090-0.840 mug/L, and 94.8-102%, respectively. Our results showed the median of total PAHs and PAH4 (in all samples) were 7.67 +/- 3.19 and 0.370 +/- 0.160 mug/L, respectively. The median of BaP in samples was )0.060 +/- 0.030 mug/L( lower than the standard level (0.200 mug/L in drinking water) of US Environmental Protection Agency (USEPA). Also, our results showed that pineapple juice had a maximum median of total PAHs of 12.4 +/- 4.84 mug/L and mango juice had a minimum median of total PAHs of 5.17 +/- 1.24 mug/L. Additionally, canned packaging had a maximum average total PAHs of 10.6 +/- 5.22 mug/L and PET bottles had a minimum average total PAH of 5.25 +/- 2.03 mug/L. A heat map approach was also used to cluster samples. The Monte Carlo results indicated that the estimated daily intake (EDI) rank order was Na > B(g)P > Ch > I(cd)P > B(b)F > Ph > B(k)F > F > Ace > Fl > B(a)P > B(a)A > P >A. The Monte Carlo simulation (MCS) results showed the incremental lifetime cancer risk (ILCR) at the 95th percentiles for adults and children was 4.91 x 10(-7) and 9.12 x 10(-7), respectively. It is concluded that the concentration of PAHs compounds in Iranian fruit juices is lower than the existing standards, and in terms of the risk of carcinogenesis, it does not threaten the human health (< 10(-6)). CI - (c) 2022. The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature. FAU - Naghashan, Mahsa AU - Naghashan M AD - Department of Food Science and Technology, Ferdowsi University of Mashhad, Mashhad, Iran. FAU - Kargarghomsheh, Pegah AU - Kargarghomsheh P AD - Department of Food Science, University of Massachusetts, Amherst, MA, 01003, USA. FAU - Nazari, Roshanak Rafiei AU - Nazari RR AD - Department of Physics, South Tehran Branch, Islamic Azad University, Tehran, Iran. FAU - Mehraie, Abbas AU - Mehraie A AD - Department of Food Hygiene and Aquaculture, Faculty of Veterinary Medicine, Ferdowsi University of Mashhad, Mashhad, Iran. FAU - Tooryan, Fahimeh AU - Tooryan F AD - Department of Food Hygiene, Faculty of Veterinary Medicine, Amol University of Special Modern Technologies, Amol, Iran. AD - Preventive Veterinary Medicine Graduate Group, School of Veterinary Medicine, University of California, Davis, CA, USA. FAU - Shariatifar, Nabi AU - Shariatifar N AUID- ORCID: 0000-0002-2861-5758 AD - Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran. nshriatifar@ut.ac.ir. LA - eng PT - Journal Article DEP - 20221017 PL - Germany TA - Environ Sci Pollut Res Int JT - Environmental science and pollution research international JID - 9441769 RN - 0 (Polycyclic Aromatic Hydrocarbons) SB - IM MH - Adult MH - Child MH - Humans MH - Iran MH - Fruit and Vegetable Juices/analysis MH - Risk Assessment MH - *Neoplasms MH - Gas Chromatography-Mass Spectrometry MH - *Polycyclic Aromatic Hydrocarbons/analysis OTO - NOTNLM OT - Benzo(a)pyrene (BaP) OT - Estimated daily intake (EDI) OT - Incremental lifetime cancer risk (ILCR) OT - MSPE-GC/MS method OT - Packaging EDAT- 2022/10/18 06:00 MHDA- 2023/02/22 06:00 CRDT- 2022/10/17 11:23 PHST- 2022/06/08 00:00 [received] PHST- 2022/08/24 00:00 [accepted] PHST- 2022/10/18 06:00 [pubmed] PHST- 2023/02/22 06:00 [medline] PHST- 2022/10/17 11:23 [entrez] AID - 10.1007/s11356-022-22763-w [pii] AID - 10.1007/s11356-022-22763-w [doi] PST - ppublish SO - Environ Sci Pollut Res Int. 2023 Feb;30(8):20077-20088. doi: 10.1007/s11356-022-22763-w. Epub 2022 Oct 17.