PMID- 36252512
OWN - NLM
STAT- MEDLINE
DCOM- 20221108
LR  - 20221108
IS  - 1090-2414 (Electronic)
IS  - 0147-6513 (Linking)
VI  - 246
DP  - 2022 Nov
TI  - Contrasting dynamics of manure-borne antibiotic resistance genes in different 
      soils.
PG  - 114162
LID - S0147-6513(22)01002-8 [pii]
LID - 10.1016/j.ecoenv.2022.114162 [doi]
AB  - Antibiotic resistance genes (ARGs) are important biological contamination factors 
      in soil systems, posing direct or indirect threats to soil health, food safety 
      and human health. The ubiquitous pollution of ARGs is usually implicated with the 
      application of organic manures in agricultural soil ecosystem. However, little is 
      known about the transmission and fate of ARGs after manure input concerning 
      different soils. Herein, the transmission potential and temporal dynamics of 
      manure-associated ARGs was characterized with three different agricultural soils 
      collected from Jiangxi (JX), Zhejiang (ZJ), and Jilin (JL), respectively. The 
      results show that manure input did not affect the total abundance of ARGs in the 
      receiving soils, but remarkedly alter the compositions of ARGs in soils. The 
      manure-associated ARGs were significantly enriched in the manure-amended soils, 
      including genes conferring resistance to sulfonamide, aminoglycoside, 
      tetracycline, chloramphenicol, and trimethoprim with the fold of 1.97 - 27.86. 
      Variance partitioning analysis showed that the major variances of ARG community 
      was explained by mobile genetic elements and bacterial profile (> 76%) but not 
      the concentrations of heavy metals and antibiotics. Furthermore, 31, 37, and 38 
      ARG subtypes were identified as the potential extrinsic ARGs derived from manures 
      in the JX, ZJ, and JL soils, respectively, including 13 shared ARG subtypes. It 
      was also found that the manure-associated ARGs (aadA, sul1, sul2, tetC, and tetG) 
      declined with the incubation time in the JX and ZJ soils, whereas they firstly 
      decreased and then increased in the JL soil. The abundance of these five ARGs in 
      the JL soil was significantly higher than that in the JX and ZJ soils. 
      Collectively, this finding revealed that soil type was responsible for the 
      transmission and fate of manure-associated ARGs in agroecosystem.
CI  - Copyright (c) 2022 The Authors. Published by Elsevier Inc. All rights reserved.
FAU - Zhang, Houpu
AU  - Zhang H
AD  - College of Resources and Environment, Anhui Agricultural University, Key 
      Laboratory of Agri-food Safety of Anhui Province, Hefei 230036, China; Research 
      Academy of Green Development of Anhui Agricultural University, Hefei 230036, 
      China.
FAU - Ling, Hong
AU  - Ling H
AD  - College of Resources and Environment, Anhui Agricultural University, Key 
      Laboratory of Agri-food Safety of Anhui Province, Hefei 230036, China.
FAU - Zhou, Ruofei
AU  - Zhou R
AD  - College of Resources and Environment, Anhui Agricultural University, Key 
      Laboratory of Agri-food Safety of Anhui Province, Hefei 230036, China.
FAU - Tang, Jun
AU  - Tang J
AD  - College of Resources and Environment, Anhui Agricultural University, Key 
      Laboratory of Agri-food Safety of Anhui Province, Hefei 230036, China; Research 
      Academy of Green Development of Anhui Agricultural University, Hefei 230036, 
      China.
FAU - Hua, Rimao
AU  - Hua R
AD  - College of Resources and Environment, Anhui Agricultural University, Key 
      Laboratory of Agri-food Safety of Anhui Province, Hefei 230036, China; Research 
      Academy of Green Development of Anhui Agricultural University, Hefei 230036, 
      China.
FAU - Wu, Xiangwei
AU  - Wu X
AD  - College of Resources and Environment, Anhui Agricultural University, Key 
      Laboratory of Agri-food Safety of Anhui Province, Hefei 230036, China; Research 
      Academy of Green Development of Anhui Agricultural University, Hefei 230036, 
      China. Electronic address: wxw@ahau.edu.cn.
LA  - eng
PT  - Journal Article
DEP - 20221014
PL  - Netherlands
TA  - Ecotoxicol Environ Saf
JT  - Ecotoxicology and environmental safety
JID - 7805381
RN  - 0 (Manure)
RN  - 0 (Soil)
RN  - 0 (Anti-Bacterial Agents)
SB  - IM
MH  - Humans
MH  - *Manure/microbiology
MH  - *Soil
MH  - Anti-Bacterial Agents/pharmacology
MH  - Ecosystem
MH  - Soil Microbiology
MH  - Genes, Bacterial
MH  - Drug Resistance, Microbial/genetics
OTO - NOTNLM
OT  - Agricultural soil
OT  - Antibiotic resistance genes
OT  - Manure
OT  - Temporal dynamic
OT  - Transmission potential
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2022/10/18 06:00
MHDA- 2022/11/09 06:00
CRDT- 2022/10/17 18:31
PHST- 2022/06/15 00:00 [received]
PHST- 2022/09/21 00:00 [revised]
PHST- 2022/10/04 00:00 [accepted]
PHST- 2022/10/18 06:00 [pubmed]
PHST- 2022/11/09 06:00 [medline]
PHST- 2022/10/17 18:31 [entrez]
AID - S0147-6513(22)01002-8 [pii]
AID - 10.1016/j.ecoenv.2022.114162 [doi]
PST - ppublish
SO  - Ecotoxicol Environ Saf. 2022 Nov;246:114162. doi: 10.1016/j.ecoenv.2022.114162. 
      Epub 2022 Oct 14.